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pdxY

Victor ID 605
Gene Name pdxY
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191321
NCBI Protein GI 56707442
Locus Tag FTT0288c
Protein Accession YP_169338.1
Other Database IDs UniProtKB-ID: Q5NI04_FRATT
UniRef100: UniRef100_Q14JF6
UniRef90: UniRef90_Q14JF6
UniRef50: UniRef50_Q14JF6
UniParc: UPI000049C24A
EMBL: AJ749949
EMBL-CDS: CAG44921.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG661459
OMA: CPNQLEL
ProtClustDB: CLSK934459
Taxonomy ID 177416
Gene Starting Position 302414
Gene Ending Position 303265
Gene Strand (Orientation) -
Protein Name Pyridoxal/pyridoxine/pyridoxamine kinase
DNA Sequence 
>gi|56707187:302414-303265 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATTATCTAATATACTCCTGTGCTTGAATTAATGCTAGCTCATCCGTGTTTAATTGATAAGTTGTCCTAAA
GATACCATCTAAGCACTGTGTTACTGCTTTGAGAGTTTCATCTAAGTTTTTACCTTTTAACAGATAACTT
AAAAACATTGCTGCTGTAATATCGCCGGAGCCGCTAACCTTAGGTTGAACCTTGTATTTAGGAGATTCAA
GATATGAGAAGTTACCATGGTGGTATATGGCTATACCAGTTTTATCTTTACTAAATGATACGCTGGTTAC
GATTATTATTTGGTTATGATTTCTTGTTTTGCTAATAAGCTTTTTACAAGCTGTAATGATATCATCATAA
TTACATATTTGAGAATCACTTAAAACACTAAGCTCGAATAGATTAGGCGTGATAATATCGGCTAAAGGCA
ATAAGTGGCTTAAAAAAATATTAGGGTGATCAGCAGATGCAAAAATATGGCCGTTTTCATCTTCATCATG
CTTGTCACCAAAGACAGGGTCACAGCAATATAAACTATCGCTGTTTAACTTTTTAAGCTCTATAACAGTA
TTTGCAATAACCTTGGCAATCTCTAAGTTACCAATATATCCAGATAAGATGGCATTTTGTTGTGCTAAAA
AACCATTTGCTATCATACCATCGATAACATTTTGGATATCTTCAGCACTAAAGAAAGATCCTTTATAAAA
ATCATACTGAGTATGGTTTGATAGCTGTACTGTGTATATTGGCGAAACTTCTATGCCTAGTTTCTGCATT
GGGAAAACTGCTGCTTTATTACCGGCATAGCCATAGGCGACATGAGATTGGATAGATAATACTTTAGGGA
TTTTTAAAGACA
Protein Sequence 
>gi|56707442|ref|YP_169338.1| pyridoxal kinase [Francisella tularensis subsp. tularensis SCHU S4] MSLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSAEDIQNVIDGMIANGFLAQQNAILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGDKHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSVLSDSQICNYDDIITACKKLISKTRNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSYLLKGKNLDETLKAVTQCLDGIFRTTYQLNTDELALIQAQEYIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pdxY mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG2240H, under H: Coenzyme transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].