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ruvB

Victor ID 601
Gene Name ruvB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191291
NCBI Protein GI 56708102
Locus Tag FTT1013c
Protein Accession YP_169998.1
Other Database IDs UniProtKB-ID: RUVB_FRATT
UniRef100: UniRef100_Q14HJ6
UniRef90: UniRef90_B0U0B6
UniRef50: UniRef50_B0TF70
UniParc: UPI00004502A7
EMBL: AJ749949
EMBL-CDS: CAG45646.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG339960
OMA: EKFDGGP
ProtClustDB: PRK00080
Taxonomy ID 177416
Gene Starting Position 1023158
Gene Ending Position 1024204
Gene Strand (Orientation) -
Protein Name Holliday junction DNA helicase B
DNA Sequence 
>gi|56707187:1023158-1024204 Francisella tularensis subsp. tularensis Schu 4, complete genome
CTTATATTGATAGAGTTTGTTGTTGATCTGCACTTAAGTTATCTGGGATTTTTAATTTGAAATGGTTATA
TGCTAATAGAGTCGCAATACGTCCTCTAGCTGTACGCATAATATAGCCCTGTTGAATTAAATAAGGTTCA
ATAACATCCTCAATGGTACCCTTTTCTTCACTTAAAGCTGCTGACATTGTATCTAGTCCCACCGGTCCAC
CAGCAAATTTTTCCATTAATGTAAGCAAATACCTATGATCCATATGATCAAAACCAACAGGATCGACTTT
AAGCATACTCAAAGCTTTATCAGCAATTTCAAAGCAGATTACTCCAGAACCTTTAACTTGAGCGTAGTCC
CTTACTCTACGCAAAAGTCTATTAGCAATTCTAGGTGTTCCCCTTGAGCGTTTTGCAATCTCCATTGCGC
CATCAGTAGTAATATCTAGATTTAATAACTTTGCTGAACGATAAACAATTTTTGACAAATCATCTATCGA
ATAAAACTCTAGTCGCTGGATAATACCAAATCTATCACGCAAAGGTGATGTCAAAAGCCCTGCTCTTGTA
GTTGCTCCAACTAATGTAAACGGCGGTAAATCAATTTTTATAGATCTCGCTGCTGGACCTTCACCTATCA
TTATATCAAGTTGGTAGTCCTCCATAGCAGGATAGAGAATCTCTTCTACAACTGGACTTAAGCGATGAAT
TTCATCAATAAATAACACATCATTCTCTTCAAGATTAGTCAAAAGTGCAGCTAAATCACCAGCTTTTTCT
AGAACTGGACCACTTGTCTGCTTAAGCTCAACCCCCATCTCATTGGCAATAATATTTGATAAGGTTGTTT
TGCCTAAGCCAGGAGGTCCAAATATAAGTGTATGATCAAGAGCATCTTTACGTGCTTTTGCTGCTTGAAT
AAAAATCTCCATCTGTTCGCGTACAGCTGGTTGACCCTCATACTCTGCCAAAGTTTTTGGTCTAATAGCT
CTATCTATAACATTTTCATCATTGGTTTGAGCTGTATTAGCTGAGATTATTCTATCTGTTTCGATCA
Protein Sequence 
>gi|56708102|ref|YP_169998.1| Holliday junction DNA helicase RuvB [Francisella tularensis subsp. tularensis SCHU S4] MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANEMGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKGSGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGRIATLLAYNHFKLKIPDNLSADQQQTLSI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ruvB mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG2255L, under L: Replication, recombination and repair
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].