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pcs

Victor ID 600
Gene Name pcs
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191290
NCBI Protein GI 56708590
Locus Tag FTT1563
Protein Accession YP_170486.1
Other Database IDs UniProtKB-ID: Q5NEQ6_FRATT
UniRef100: UniRef100_A4IWK1
UniRef90: UniRef90_A4IWK1
UniRef50: UniRef50_A4IWK1
UniParc: UPI000049C589
EMBL: AJ749949
EMBL-CDS: CAG46196.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG675964
OMA: FLHPFRV
ProtClustDB: CLSK865517
Taxonomy ID 177416
Gene Starting Position 1625074
Gene Ending Position 1625838
Gene Strand (Orientation) +
Protein Name phosphatidylcholine synthase
DNA Sequence 
>gi|56707187:1625074-1625838 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGCAAGTACAAACGATACAAAAAATATATGCTTGGCTAGTGCATCTTTTTACATCATTAGGTGCCGTG
TTCGGTATCTTAGCTATTATATTTTCAATAGAGGCTGCTAAAACAATTGTATTAGGTCAAACAGATCTAC
ATCACTACTATATTAAGCTTTCTATGTTTAGTATTATAATGGCGATATTTATTGATTCGATAGATGGTAG
CTTAGCAAGACTAGTTGATATCAAAAAACTTGCTCCTATAGATGGCGCCCTTCTTGATAATATTATAGAC
TTTACAACATATTCAATTGTTCCTTGTATCTGGATATATGTATCAGCAGTAGTTAGCCAACAATGGCTAA
TCCCAATAATAATAATGATAACTATCTCCTCCTCATATCAGTTCTGTCAGCTAAATGCAAAAACTGATGA
TTATTTTTTTGTCGGTTTCCCAAGCTACTGGAATGTAATTGTAATGTATATGCTATGTTTTCAGTCAAAC
CAATTAATTAATGAAATAATGATAACGATATTATCAATATTTTCTTTTATACCAATTAAATATATTTATC
TATCAAGAACTGAACATATCAGTAAGAGTAAACTTGTCAAAATATTCACTTTTATTTTCACAATGTTAGC
AGCTATTGCAACTTTCCTAGCGGTATTACTTTATCCATTAAAAACGCCAACACCACTGGTAACAATAATA
TTAGTGTTTACAATATTTTATATAATCTTTAGTCTAAAACTAAATATTAAACCTGTAAAAAGTTA
Protein Sequence 
>gi|56708590|ref|YP_170486.1| phosphatidylcholine synthase [Francisella tularensis subsp. tularensis SCHU S4] MQVQTIQKIYAWLVHLFTSLGAVFGILAIIFSIEAAKTIVLGQTDLHHYYIKLSMFSIIMAIFIDSIDGSLARLVDIKKLAPIDGALLDNIIDFTTYSIVPCIWIYVSAVVSQQWLIPIIIMITISSSYQFCQLNAKTDDYFFVGFPSYWNVIVMYMLCFQSNQLINEIMITILSIFSFIPIKYIYLSRTEHISKSKLVKIFTFIFTMLAAIATFLAVLLYPLKTPTPLVTIILVFTIFYIIFSLKLNIKPVKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pcs mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG1183I, under I: Lipid transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].