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cadA

Victor ID 598
Gene Name cadA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191271
NCBI Protein GI 56707555
Locus Tag FTT0406
Protein Accession YP_169451.1
Other Database IDs UniProtKB-ID: Q5NHP1_FRATT
UniRef100: UniRef100_A4IZK9
UniRef90: UniRef90_A4IZK9
UniRef50: UniRef50_P05033
UniParc: UPI000049C29A
EMBL: AJ749949
EMBL-CDS: CAG45039.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG301265
OMA: FKYVEEG
ProtClustDB: CLSK873924
Taxonomy ID 177416
Gene Starting Position 411546
Gene Ending Position 413687
Gene Strand (Orientation) +
Protein Name lysine decarboxylase, inducable
DNA Sequence 
>gi|56707187:411546-413687 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGAAAACTGTTGTATTTGTCTATAAAGATACCTTAAAGTCATATAAGGAAAAATTTTTACTAAAAATT
GAGAAAGATCTTAAAAATCATCATGAGTATTATACTTTGAAGCTTGATGATTTATCCGAAGTGGTTGAAA
TTCTTGAGGAGAACTCTAGAATATGCTGTATTGTTTTAGATAGAGCTAGTTTCAATATTGAAGCTTTTCA
TAATATTGCGCACCTTAATACAAAGCTGCCAATATTTGTAGCATCTGACTATAGTCAAAGTATTAAGCTT
AATCTGCGTGATTTTAATCTAAATATCAACTTCTTGCAGTATGATGCTTTAGCTGGTGAGGATTCTGACT
TTATTCACAAAACTATCACAAATTATTTTAATTATATATTGCCACCGTTGACTTATGAGTTATTTAAGTA
CTCTAAATCTTTTAATTCGGCTTTTTGTACTCCAGGTCACCAAGGAGGTTATGGTTTTCAGCGTTCTGCA
GTAGGGGCTTTGTTTTATGATTTTTATGGCGAGAATATTTTTAAGACGGATTTATCTATTTCAATGAAAG
AGCTGGGAAGCTTGCTTGATCATTCTGAAGCACATAAGGACGCTGAAGAATATATATCTAAAGTTTTTAA
ATCAGACAGATCACTTATTGTTACAAATGGTACTTCAACAGCTAATAAAATAGTGGGAATGTATAGTGTT
GCTGATGGTGATACGATTCTTGTAGATAGAAATTGCCATAAATCAGTGACACATCTAATGATGATGGTTG
ATGTTAACCCAATATATCTAAAACCAACCAGAAATGCTTATGGAATAATTGGTGGGATTCCTAAAAAAGA
GTTCAAAAGAGAAACTATCCAAGAAAAGATAGATAATAGTAATATTGCTGATAAGTGGCCTGAATATGCG
GTAGTTACAAACTCAACTTATGACGGTATCCTTTATAATACTGATACGATACATCGAGAGCTTGATGTTA
AAAAACTACATTTTGATAGTGCTTGGATACCATATGCAATATTTCATCCAATTTATAAGCATAAATCAGC
AATGCAAATTGAGCCAAGACCAGAACATATAATTTTTGAAACACAGTCAACACATAAACTTTTAGCGGCC
TTTAGCCAATCATCAATGCTGCATATAAAAGGCGACTATAATGAAGAAGTATTAAATGAAGCGTTTATGC
TGCATACTTCAACATCACCTTTTTATCCGATAGTTGCTAGCGTGGAAACAGCAGCAGCAATGATGGAGGG
CGAGCAAGGCTATAATCTTATCGACAAGACTATTAACTTAGCTATAGATTTTAGAAGAGAACTAATCAAA
CTAAGATCTGAAGCAAATGGTTGGTTTTTTGATGTTTGGCAACCTGATAATATCTCTAATAAAGAGGCAT
GGCTTCTGAGAAATGGTGATAAATGGCATGGATTTAAAAATGTTGATGGTGATTTTCTCTCATTAGACCC
TATCAAAATAACAATTCTAACTCCTGGGATAAAAGATAATGATGTTCAAGATTGGGGAGTACCAGCTGAT
GTGGTCGCTAAATTCTTAGATGAGCATGATATTGTGGTTGAGAAGTCTGGACCATATTCATTACTATTTA
TATTTAGTTTAGGTACAACAAAAGCTAAATCAGTAAGGCTAATTTCGGTATTGAATAAATTCAAACAAAT
GTATGATGAAAATACACTTGTTGAAAAAATGCTACCAACTTTATATGCGGAAGATCCTAAATTTTATGAA
GATATGAGAATTCAAGAAGTTAGTGAAAGATTACATCAGTATATGAAAGAGGCTAATCTTCCTAATCTCA
TGTATCATGCTTTTAATGTGCTACCAGAGCAACAGCTAAATCCTCATAGGGCTTTTCAGAAATTATTAAA
AGGTAAGGTTAAAAAGGTTCCTCTAGTAGAACTGTATGAGCATACTTCAGCTGTTATGATATTACCTTAT
CCACCTGGGATACCTGTTATTTTTCCTGGAGAGAAGATAACCGAAGAATCTAAAGTAATATTGGATTTCT
TATTAATGCTTGAGAAAATAGGTTCGATGTTGCCTGGCTTTGATACAGATATTCATGGTCCTGAGAGGGC
AAAAGATGGTAAGCTCTATATCAAAGTTATTGATGATAAATA
Protein Sequence 
>gi|56707555|ref|YP_169451.1| lysine decarboxylase, inducable [Francisella tularensis subsp. tularensis SCHU S4] MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLPIFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQRSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVADGDTILVDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTIHRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTSTSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNGDKWHGFKNVDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQMYDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVELYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cadA mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG1982E, under E: Amino acid transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].