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FTT0584

Victor ID 590
Gene Name FTT0584
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191177
NCBI Protein GI 56707712
Locus Tag FTT0584
Protein Accession YP_169608.1
Other Database IDs UniProtKB-ID: Q5NH84_FRATT
UniRef100: UniRef100_Q14IN6
UniRef90: UniRef90_A4IZ15
UniRef50: UniRef50_A4IZ15
UniParc: UPI000049C311
EMBL: AJ749949
EMBL-CDS: CAG45217.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG485623
OMA: RTARRHQ
ProtClustDB: CLSK713870
Taxonomy ID 177416
Gene Starting Position 601162
Gene Ending Position 604533
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|56707187:601162-604533 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGAATGTCAAAATATTACCAATAGCAATAGATTTAGATGTTAAAAATACTGGTGTCTTTAGCGCATTT
TATCAAAAAGGAACTTCTCTTGAGAAATTGGATAATAAAAATGGCAAAGTATATGAACTATCAAAAGATT
CTTATACTTTATTAATGAATAATAGAACAGCACGAAGACATAAAAGAAGAGGAATAGATAGAAAGCAGCT
AGTCAAAAGGCTCTTTAAGCTTGTTTGGACAGAGCAACTAAATTTAGAGTGGGATAAAGACACTCAACAA
GCGATTAGCTTTTTGTTTAATCGTAGAGGTTTTAGTTTTATTACTGATGGTTATTCGACTGAATATTTAA
ATATTGTTCCAGAGCAAGTAAAAGCGATACTTATGGATATATTTGATGATTACAACGGTGAAGATGATTT
AGACAGTTATTTAAAATTAGCTACTGAGCAAGAAAGCAAAATTTCTGAAATATATAACAAGCTAATGCAA
AAAATATTAGAGTTTAAATTAAGGAAATTATGTACTGATATTAAGGATGATAAAGTAAGTACTAAAACAC
TTAAAGAAATCACAAGCTATGAATTTGAGTTATTAGCTGATTATTTAGCAAACTATAGCGAGAGTTTAAA
AACACAAAAATTTAGTTATACAGATAAACAAGGTAATTTAAAAGAGCTAAGCTACTATCATCATGATAAA
TATAATATTCAAGAATTTCTAAAGCGACATGCTACTATAAATGATGAAATTTTAGGTACTCTTTTAACTG
ATGATTTTGATATTTGGAATTTTAATTTTGAGAAATTTGATTTTGATAAGAATGAAGAAAAGCTTCAGAA
TCAGGAAGATAAAGATCATACACAAGCGCATTTACATCATTTTGTTTTTGTAGTAAATAAAATAAAAAGT
GAGATGGCAAGTGGTGGTCGTCATCGTAGCCAATATTTTCAAGAGATAACAAATGTGCTAGATGAAAATA
ATCACCAAGAAGGATATCTCAAGAATTTCTGTGAAAATTTGCATAATAAAAAATATTCAAATTTAAGTGT
TAAAAATTTAGTTAATCTAGTTGGTAACCTAAGTAATTTAGAGCTAAAACCGCTAAGAAAATATTTTAAT
GACAAAATTCATGCAAAAGCTGATCATTGGGATGAGCAAAAGTTTACAGAAACTTATTGCCACTGGATAT
TAGGAGAGTGGCGAGTAGGTGTCAAAGATCAAGATAAGAAAGATGGTGCTAAATATAGTTATAAAGATCT
GTGTAATGAATTAAAACAAAAGGTTACTAAGGCTGGTTTGATAGATTTTTTATTAGAGTTAGATCCATGC
AGAACTATACCACCATATCTGGATAACAATAACCGTAAACCACCAAAATGTCAAAGTTTGATTTTAAATC
CGAAGTTTTTAGATAATCAATATCCAAACTGGCAACAATATTTACAAGAATTAAAGAAACTGCAAAGTAT
TCAAGATTATTTAGACAGTTTTGAAACTGATTTAAAAGACTTAAAGTCAAGTAAAGATCAACCATATTTT
GTTGAATACAAGAGTTCAAATCAGCAAATGGCAAGTGGTCAAAGAGATTATAAAGATTTAGATGCTCGAA
TATTACAGTTTATATTTGATAGGGTAAAAGCTAGCGATGAGTTGCTTTTGAATGAGATTTATTTTCAGGC
TAAAAAACTTAAACAAAAAGCTAGCTCTGAGTTAGAAAAACTCGAGTCGAGCAAAAAGCTAGATGAAGTT
ATAGCAAATAGTCAACTATCACAGATACTAAAGTCTCAACATACAAATGGTATTTTTGAACAGGGTACTT
TTTTGCATTTAGTTTGTAAATACTATAAACAAAGACAAAGAGCGAGAGACTCTAGGCTATATATTATGCC
TGAATATCGTTATGATAAAAAACTAGATAAATATAACAATACAGGCAGATTTGATGATAATAATCAGCTA
TTAACATATTGTAATCATAAGCCAAGACAAAAAAGATACCAATTGTTAAATGATTTAGCTGGGGTGTTAC
AGGTATCTCGTAATCAGTTGCTAAGTTCAGTTGAAGAGTGGTTTCAACAAGCACAACGAGTTGGTGAAAT
ATCAAAATCTCAAGATGAGCAAATATTTGAATGGTTAAAAAGCTTTAAAATAGCTAGTTATTGTAAAGCC
GCGGTGGAAATGCAAAAACAATATCGAGGAACTTTAAAAAACGCGATTCAAACTGCTATATTTAGACAAA
GTGAAAATATAAACAAAAATAAAAATACTGGTAATCAACAACAAGCACTTTCAGAAAATTCCAAAGATGT
AAAATCACTAACAGCGGACGAGAAAAAACTCCTAAAACTAATAGAAAATATAGCTAAAGCATCACAGAAA
ATAGGTGAAAGTTTAGGACTAAATGATAAGCAAATTAAAAAATTTAACTCAATATATAGTTTTGCACAGA
TTCAACAAATTGCTTTTGCAAAGCGTAAAGGTAATGCTAACACTTGTGCAGTTTGTAGTGCTGATAATGC
TCATAGAATGCAACAAATTAAGATCACTGAGCTTGTAGAGGACAATAAAGATAACATAATCTTAAGTGCC
AAAGCTCAGAGACTACCAGCGATACCAACTAGAATAGTTGACGGTGCGGTTAAGAAAATGGCAACTATAT
TAGCTAAAAATATAGTTGATGATAATTGGCAGAATATCAAACAAGTTTTATCAGCAAAACATCAGTTACA
TATACCTATTATCACAGAATCAAATGCTTTTGAGTTTGAACCAGCATTAGCTGATGTAAAAGGTAAGAGC
CTAAAAGATAGGAGAAAAAAAGCATTAGAGAGAATAAGTCCTGAAAATATATTCAAGGATAAAAACAATA
GAATAAAAGAATTTGCTAAAGGTATATCAGCATATAGTGGTGCTAATTTAACTGATGGCGATTTTGATGG
TGCAAAAGAAGAATTAGATCATATAATACCTCGTTCACATAAAAAATACGGCACTCTAAATGATGAAGCA
AATCTAATTTGTGTAACTCGTGATGATAATAAAAATATTTTTGCTATAGATACTAGTAAATGGTTCGAAA
TAGAAACACCTAGTGATCTTAGAGACATTGGAGTAGCAACAATTCAATACAAGATAGATAATAATTCTCG
TCCTAAAGTCAGAGTTAAACTTGATTATGTTATCGATGATGATAGTAAGATAAATTATTTTATGAATCAT
TCTTTATTAAAATCAAGATATCCTGACAAAGTTTTAGAAATTTTAAAACAATCAACTATTATAGAATTTG
AAAGTTCAGGTTTTAATAAAACTATCAAAGAAATGCTTGGTATGACATTAGCAGGTATTTATAATGAAAC
ATCTAATAATTA
Protein Sequence 
>gi|56707712|ref|YP_169608.1| hypothetical protein FTT_0584 [Francisella tularensis subsp. tularensis SCHU S4] MNVKILPIAIDLDVKNTGVFSAFYQKGTSLEKLDNKNGKVYELSKDSYTLLMNNRTARRHKRRGIDRKQLVKRLFKLVWTEQLNLEWDKDTQQAISFLFNRRGFSFITDGYSTEYLNIVPEQVKAILMDIFDDYNGEDDLDSYLKLATEQESKISEIYNKLMQKILEFKLRKLCTDIKDDKVSTKTLKEITSYEFELLADYLANYSESLKTQKFSYTDKQGNLKELSYYHHDKYNIQEFLKRHATINDEILGTLLTDDFDIWNFNFEKFDFDKNEEKLQNQEDKDHTQAHLHHFVFVVNKIKSEMASGGRHRSQYFQEITNVLDENNHQEGYLKNFCENLHNKKYSNLSVKNLVNLVGNLSNLELKPLRKYFNDKIHAKADHWDEQKFTETYCHWILGEWRVGVKDQDKKDGAKYSYKDLCNELKQKVTKAGLIDFLLELDPCRTIPPYLDNNNRKPPKCQSLILNPKFLDNQYPNWQQYLQELKKLQSIQDYLDSFETDLKDLKSSKDQPYFVEYKSSNQQMASGQRDYKDLDARILQFIFDRVKASDELLLNEIYFQAKKLKQKASSELEKLESSKKLDEVIANSQLSQILKSQHTNGIFEQGTFLHLVCKYYKQRQRARDSRLYIMPEYRYDKKLDKYNNTGRFDDNNQLLTYCNHKPRQKRYQLLNDLAGVLQVSRNQLLSSVEEWFQQAQRVGEISKSQDEQIFEWLKSFKIASYCKAAVEMQKQYRGTLKNAIQTAIFRQSENINKNKNTGNQQQALSENSKDVKSLTADEKKLLKLIENIAKASQKIGESLGLNDKQIKKFNSIYSFAQIQQIAFAKRKGNANTCAVCSADNAHRMQQIKITELVEDNKDNIILSAKAQRLPAIPTRIVDGAVKKMATILAKNIVDDNWQNIKQVLSAKHQLHIPIITESNAFEFEPALADVKGKSLKDRRKKALERISPENIFKDKNNRIKEFAKGISAYSGANLTDGDFDGAKEELDHIIPRSHKKYGTLNDEANLICVTRDDNKNIFAIDTSKWFEIETPSDLRDIGVATIQYKIDNNSRPKVRVKLDYVIDDDSKINYFMNHSLLKSRYPDKVLEILKQSTIIEFESSGFNKTIKEMLGMTLAGIYNETSNN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT0584 mutant is severely attenuated in mice (Weiss et al., 2007).
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].