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trpG

Victor ID 577
Gene Name trpG
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190985
NCBI Protein GI 56708043
Locus Tag FTT0946
Protein Accession YP_169939.1
Other Database IDs UniProtKB-ID: Q5NGA3_FRATT
UniRef100: UniRef100_Q14HQ5
UniRef90: UniRef90_Q14HQ5
UniRef50: UniRef50_B2SGR3
UniParc: UPI000045018E
EMBL: AJ749949
EMBL-CDS: CAG45579.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG292341
OMA: HGKQSIL
ProtClustDB: CLSK934765
Taxonomy ID 177416
Gene Starting Position 958196
Gene Ending Position 958750
Gene Strand (Orientation) +
Protein Name anthranilate synthase component II
DNA Sequence 
>gi|56707187:958196-958750 Francisella tularensis subsp. tularensis Schu 4, complete genome
GATGGTTTTATATATCGATCATTATGATTCATTTAGTAGTACGATTGTCGATTATATAACTTATCTTGGC
TATCAAGTGTCGATGCTAAAAACTGATGAGCAAATTGATAATATTGACCAATATTCTCATATCATTATTG
GTCCAGGACCAGGTCACCCGGATGAGCTTAAAAATATCTATCCAATTATTGAATACTGTCAGCAAAAAAA
ATTACCTTTGTTAGGAATATGTTTAGGTCATCAGCTTATTGCTCAATATTATGGTGCAAAAATCATAAAA
GCTAAACAAATATACCATGGCAAACTCTCCGAGATTAAACAGCTTCAATCATCAGCATTATATAAAGATC
ATCCAGTGAAATTTGCTGTAATACGTTATCATTCATTAATTGTTAATGATATTAAAGAGCCTTTGATTAC
TTTAGCTGCAACCGATAATCATGAAATTATGGCTTTTGCTCATCAAAATGCAAAGATTTTTGGGGTACAA
TATCATCCAGAAGCATATTTGACAGAATATGGCTTAGCAACATTGAAAAACTTCTTGAGTATTTG
Protein Sequence 
>gi|56708043|ref|YP_169939.1| anthranilate synthase subunit II [Francisella tularensis subsp. tularensis SCHU S4] MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIYPIIEYCQQKKLPLLGICLGHQLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVKFAVIRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIFGVQYHPEAYLTEYGLATLKNFLSI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trpG mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0512EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].