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bioB

Victor ID 574
Gene Name bioB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190968
NCBI Protein GI 56708034
Locus Tag FTT0937c
Protein Accession YP_169930.1
Other Database IDs UniProtKB-ID: BIOB_FRATT
UniRef100: UniRef100_Q14HR4
UniRef90: UniRef90_B0U0S3
UniRef50: UniRef50_Q4FQJ9
UniParc: UPI0000450197
EMBL: AJ749949
EMBL-CDS: CAG45570.1
RefSeq_NT: NC_006570.2
HSSP: P12996
GenomeReviews: AJ749949_GR
HOGENOM: HBG405569
OMA: MGMETCM
ProtClustDB: CLSK2308449
Taxonomy ID 177416
Gene Starting Position 948397
Gene Ending Position 949338
Gene Strand (Orientation) -
Protein Name biotin synthase
DNA Sequence 
>gi|56707187:948397-949338 Francisella tularensis subsp. tularensis Schu 4, complete genome
TTTAACATAATTCAGCATTTGATTTTAAGCCAAGCTTAGCTAATAAAAAATTATCAGAATTAACAGTAGC
ATTATTTTCTGTTAATAACTTATTACCATAAAATATTGAGTTAATACCAGCAAGGAAACATAGAGTTTGA
GTTTCCAAAGACATATTTTCTCTACCTGCTGATAACCTTAGGCGTGCTTGTGGAAATAGTATTCTTGTAG
TTGCAATAAATCTTACTAATTCAAAACTATCAATTTGTGCATTTGTATACTTATCTCCTAAAGGAGTTCC
TTTAATAGGTATTAATGTATTGATAGGAATACTTTTTGGAGCAGCAGGTAGTTGTAATAACTCTAGTAAT
AAATTAAATCTATCATCTAGAGATTCGCCCATACCCAATATACCACCACAACAGACATTTATATCGGCGT
TAGCAACATTTCTAATAGTTTCAATTCTTTCTTCAAATTTACGTGTGGTAATTATTTCCGGATAAAATTC
TCTTGAAGTATCAAGATTATGATTGTAGTAATCCAATCCTGCTTGCTTTAGTTTAGTTGCTTCATCAGCA
TTAATACTTCCGAGAGTCACACATGTTTCTAAGCCAAGGTTTTTGACTTCAGTGATAATCTCAGCAACTT
GATCAAAGTCTTTTTTAGGAATGTGTTTCCAAGCAGCGCCCATACAGAACCTTTTAGATCCAGCATCTTT
AGCATTTTTTGCTTCTGCCAATATACTATCTTTATCTAATAGTTTATGCTTTTCGATACTAGTATTATAA
TGACCACTTTGAGGACAATATTTACAGTCTTCTGGGCAAGTACCAGTTTTGATACTTTTTAGTGAGCATA
ACTCGATATCATTACCAAAATTTTTATTATGAATCTCTAAAGCTTGTAAAATTAATTCTGTTAATGGTCT
TGAGTAAATTTCTTTGATTTGTTGTAATGTCA
Protein Sequence 
>gi|56708034|ref|YP_169930.1| biotin synthase [Francisella tularensis subsp. tularensis SCHU S4] MTLQQIKEIYSRPLTELILQALEIHNKNFGNDIELCSLKSIKTGTCPEDCKYCPQSGHYNTSIEKHKLLDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKDFDQVAEIITEVKNLGLETCVTLGSINADEATKLKQAGLDYYNHNLDTSREFYPEIITTRKFEERIETIRNVANADINVCCGGILGMGESLDDRFNLLLELLQLPAAPKSIPINTLIPIKGTPLGDKYTNAQIDSFELVRFIATTRILFPQARLRLSAGRENMSLETQTLCFLAGINSIFYGNKLLTENNATVNSDNFLLAKLGLKSNAELC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bioB mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0502H, under H: Coenzyme transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].