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lon

Victor ID 559
Gene Name lon
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190802
NCBI Protein GI 56707751
Locus Tag FTT0626
Protein Accession YP_169647.1
Other Database IDs UniProtKB-ID: Q5NH45_FRATT
UniRef100: UniRef100_Q14IJ7
UniRef90: UniRef90_B0TZA7
UniRef50: UniRef50_Q32JJ5
UniParc: UPI000049C331
EMBL: AJ749949
EMBL-CDS: CAG45259.1
RefSeq_NT: NC_006570.2
MEROPS: S16.001
GenomeReviews: AJ749949_GR
HOGENOM: HBG566281
OMA: IDHELEA
ProtClustDB: CLSK934601
Taxonomy ID 177416
Gene Starting Position 644646
Gene Ending Position 646970
Gene Strand (Orientation) +
Protein Name DNA-binding, ATP-dependent protease La
DNA Sequence 
>gi|56707187:644646-646970 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGTCAGAATCCCTAAATGTCGTTCCTGTTATTCCTTTAAGAGATGTTGTTATTTATCCATCGATGACT
CTACCACTTAATGTTGGGCGTAAAAAGTCAATAGAGGCAGTTAAACAGGCATCAAATAATTATAATAACT
ATATTTTATTAGCTACACAAAAAAATGGTTCGAGTGGCGGTGATGTTGTAGAAAATATATATGATATTGC
AACTCTTGCTAAAGTTGTTCAGATAATGAAACTTCCTGATGGTAGTCTGAAAATAATAGTCGAGGGTATT
GCTAAAAGACTAGTAGCTAAGTATGAAGATATTGATGGTTGTATCTATGCAAATTTAGATAGTTTACATA
TTGATGATAACTATGATCCCAGCCAAGTTGATAAAGAACTAAAAGCTATTTTACTATCAGTTTCTGATTC
GCTTAAAAGATTTGTTGATATCAGTGGCAGAGTTTCGAAAGAATCATTAGCTACATTGATAAATATGGAA
GAGCCACATAAATTTATTTATGAAATAGCTACTATACTTAATACAGAAATAGCTAAAAAACAAAAAATCC
TTGAGGCAACGGATATAAAAAATAAAGCCTTGCTACTACTTTCATATCTTTATGAAGAGCTAGAGATACT
AGAGCTAGAAGCTAAGATCAAAGATAGAGTCAAAGCTCAAGTTGATAAGAATCAGCGTGAATACTATCTA
AATGAGCAAGTCAAAGCGATATATAAAGAGCTTGGTGAAGCTGATGAAGAATCAGAAGTATCTGCTTTGA
AAAAAAGGATTGAGCATACTAAGATGTCTAAAGAGGCAAAAGAGAAATGCTTAAAAGAGCTCAAGAAACT
TAAGGCTATGCCGCCTTCTTCATCAGAATCAGCTGTTTCGAGAAACTATATTGAAACTATACTTTCTCTA
CCATGGGGTAAGAGGGCAAAAGTTAAAAGAGATATTAATCTTGCTGAGAAAGTTTTAGAAAAAGATCATT
ACGGTATCAAAAAAGTTAAAGAAAGGATCCTTGAGCATTTAGCTGTTCAGATTAAAAGAGACAGTAATAC
TAAAGCACCAATTCTGTGCTTAGTAGGACCTCCAGGAGTAGGTAAAACATCTATAGGACAGTCGATTGCT
AGAGCAACAGGGCGTGAGTATGTGCGTATGGCTTTAGGTGGTGTACGTGATGAGTCTGAGATTAGGGGAC
ATCGTCGTACATACATAGGTTCTATGCCTGGTCAAATTATCCAAAAGATAATTAAATCAAAGACAGAGAA
TCCACTTTTCTTATTAGACGAGATTGATAAAATTTCTTCTGATTTCCGTGGTGATCCATCTGCCGCGCTC
TTAGAAGTACTTGATCCAGAGCAAAATAGTACATTTAACGATCATTACCTTGAGATAGACTATGATTTAT
CAAAGGTAATGTTTGTTGCTACAGCAAATTCCTTAGATATAGATCCAGCATTACGTGATAGATTAGAGAT
TATCAACTTATCAGGCTATACCGAAATAGAGAAGCAAGCTATCGCAAAACAGTATTTAATACCTAAAGCA
TTAGAAAATAATGGTTTGACTAAGGATGAAATTAATTTCACACCAAAAGCTATCCTTGATATTATCAGAT
ATTATACAAGAGAAGCTGGTGTAAGAAATCTTCAGCAAAAAATAGATGGTGTTTGCCGTAAAGCAGTTAA
AAATCTCTTAAAGGATTCAAATACTGGCAAAATTTCGATTACACAAAAAAATCTCGAAGATTATCTTGGT
GTACATCAGTATGATTATGGTGTTAAAAATGCTAAAGCAAAAGTAGGTCAAGTAACAGGTTTAGCTTGGA
CATCTGTTGGTGGAGAGCTTTTGACTATAGAAGCTCTAGCAATGCCAGGAAAAGGTAAAGTTAAATATAC
TGGTAGTCTTGGTGATGTAATGAAAGAATCTATAGATGCTGCTTTTAGTGTGGTACGCTCAATGTCAAAA
GACTATAAGTTAGAAGATGATTTCTATGAGAAAAAAGATATACATATTCATGTCCCTGAAGGAGCTACAC
CAAAAGATGGTCCAAGTGCTGGTATTGCGATGACAACGGCTTTAGTTTCTGTATATACAAACAAACCAGT
TAGAAATGATGTGGCAATGACAGGTGAGGTGACACTCCGTGGTGAAGTGCTAGCTATAGGCGGTTTAAAA
GAAAAGCTTTTGGCAGCATTAAGAGGTGGAATTAAGGAGGTTTTGATCCCAAAACAGAATGTTAAAAATT
TAGCCGATGTTGATAAAGAAATCCTGGAAAAACTCGAAATAACCCCTGTAAGTAGCATAAAAGAGGTTTT
AGAGAGAGTTTTTTG
Protein Sequence 
>gi|56707751|ref|YP_169647.1| DNA-binding, ATP-dependent protease La [Francisella tularensis subsp. tularensis SCHU S4] MSESLNVVPVIPLRDVVIYPSMTLPLNVGRKKSIEAVKQASNNYNNYILLATQKNGSSGGDVVENIYDIATLAKVVQIMKLPDGSLKIIVEGIAKRLVAKYEDIDGCIYANLDSLHIDDNYDPSQVDKELKAILLSVSDSLKRFVDISGRVSKESLATLINMEEPHKFIYEIATILNTEIAKKQKILEATDIKNKALLLLSYLYEELEILELEAKIKDRVKAQVDKNQREYYLNEQVKAIYKELGEADEESEVSALKKRIEHTKMSKEAKEKCLKELKKLKAMPPSSSESAVSRNYIETILSLPWGKRAKVKRDINLAEKVLEKDHYGIKKVKERILEHLAVQIKRDSNTKAPILCLVGPPGVGKTSIGQSIARATGREYVRMALGGVRDESEIRGHRRTYIGSMPGQIIQKIIKSKTENPLFLLDEIDKISSDFRGDPSAALLEVLDPEQNSTFNDHYLEIDYDLSKVMFVATANSLDIDPALRDRLEIINLSGYTEIEKQAIAKQYLIPKALENNGLTKDEINFTPKAILDIIRYYTREAGVRNLQQKIDGVCRKAVKNLLKDSNTGKISITQKNLEDYLGVHQYDYGVKNAKAKVGQVTGLAWTSVGGELLTIEALAMPGKGKVKYTGSLGDVMKESIDAAFSVVRSMSKDYKLEDDFYEKKDIHIHVPEGATPKDGPSAGIAMTTALVSVYTNKPVRNDVAMTGEVTLRGEVLAIGGLKEKLLAALRGGIKEVLIPKQNVKNLADVDKEILEKLEITPVSSIKEVLERVF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a lon mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0466O, under O: Posttranslational modification, protein turnover, chaperones
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].