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surA

Victor ID 552
Gene Name surA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190745
NCBI Protein GI 56707610
Locus Tag FTT0468
Protein Accession YP_169506.1
Other Database IDs UniProtKB-ID: Q5NHI6_FRATT
UniRef100: UniRef100_Q14IY8
UniRef90: UniRef90_Q0BKP6
UniRef50: UniRef50_P81621
UniParc: UPI000049C2C5
EMBL: AJ749949
EMBL-CDS: CAG45101.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG482656
OMA: RHILIKT
ProtClustDB: CLSK986288
Taxonomy ID 177416
Gene Starting Position 486448
Gene Ending Position 487869
Gene Strand (Orientation) +
Protein Name Peptidyl-prolyl cis-trans isomerase (PPIase)
DNA Sequence 
>gi|56707187:486448-487869 Francisella tularensis subsp. tularensis Schu 4, complete genome
AGTGGGGAAACGGTATATAATGAAGAAGCTAATAACAATCTTTTTGTTGATGCTAATGTTAAATAATGCT
TATTCAGATATCTCTTCATCTATGTTTCAAAATGCTTTTAACTCGGGTATTGATGCAACATCTCCGGTAT
CAATGAATGTATCAGATAAAAAATATCTTGTGAATAAGACGGTAGCGATAGTAAATAGTAGACCAATTAC
ATCTTTTGAGCTGGATCAAGAGCTGGCTAAGCTAGAAGCTATGCAGCCAAATTCAGCCTTTAATACAGAT
CCTCTAAAAAGACAAGCATTACAAGATTTGATATCTCAGAGTGTTTTATTACAGCTTGCAGAGCGCAATA
ATATTATGATATCTAATCAACAACTAGATAGTGCTATACAAGATATTGCAGCAAAAAATGGCGTTTCAGT
AGAGTCTTTAAAGCTTAATGTCGAAGCAGCCGGAATGTCTTTTGATAGTTATAAAAAAAGAATAAGAGAT
CAGTTGATGATAAGTCAACTACAACAGCAGGCTATAGCACAGCAAGTATATGTCTCACCAGAAGAAATAC
AAAAATATATTAAAAAACATCAAAAAGAATTTGATAGGGAAATGTCGCCTGTTAAATTATATACACTTAA
AAATCTAATTGTAGCTTTGCCAGATTCTAAAAAAGCACGCCAGAAGAAAATAGATTTGTTTAAAAAACTA
GCTCTTGCAGTTAATGATGGCAGTATTGATTTTTCTGAAATTGTCAAACAGTTTTCCCAAGCGCCAAATG
CAGTTTCCGGAGGTATAGTTAGTCAACAGGTTAAATTTGATTCAATACCAGATATATATAAGGAATATAT
TAAAGAACTTAAAAATCATCAAGTTTCACAACCATTTATAGTTAATCATACATTACAGATGATATATATC
TATAACATTGATGAAAAAGCACCAATTTTAAGCAAAAAAGTAACAAAATATTATGTTTACGCAATAGAAA
TTAAGCTTGATGGTGGTATGAATGAGGACGGTGCAAAAAGTTCACTTGAAAGAGCAAAACTTGCTATTGA
GAGTGGGCAAGAATTTACTAAAGTTGCGCTGAAATATAATCAAGATTACGATCATCCAAATGGTAATTTT
AAATGGGTATCAGAGCTTGATAGTCCGCCTTCACTACCTCCTGCTGCGTTTGCACAGCTTAAGCAATTAA
AAGAAAATGAGTTGTCAGAGCCTTTTCAAGCTGATGGTAGAACTTGGATGATTATCAAATATACCAAAAC
TAAAGAGTATGATGCTGCTGAGCAGCTTAAAGAACAAAAGGCTCTAGAAGCAATATTTTCTGAAAAAGCT
CAAGAGATTTATAAAACTTGGTTAACGTCGATGAAAGATGATGCGTATATTGAAATACTTGAAGATGATT
TAAAAACACCTGAACTTTACTA
Protein Sequence 
>gi|56707610|ref|YP_169506.1| peptidyl-prolyl cis-trans isomerase [Francisella tularensis subsp. tularensis SCHU S4] MGKRYIMKKLITIFLLMLMLNNAYSDISSSMFQNAFNSGIDATSPVSMNVSDKKYLVNKTVAIVNSRPITSFELDQELAKLEAMQPNSAFNTDPLKRQALQDLISQSVLLQLAERNNIMISNQQLDSAIQDIAAKNGVSVESLKLNVEAAGMSFDSYKKRIRDQLMISQLQQQAIAQQVYVSPEEIQKYIKKHQKEFDREMSPVKLYTLKNLIVALPDSKKARQKKIDLFKKLALAVNDGSIDFSEIVKQFSQAPNAVSGGIVSQQVKFDSIPDIYKEYIKELKNHQVSQPFIVNHTLQMIYIYNIDEKAPILSKKVTKYYVYAIEIKLDGGMNEDGAKSSLERAKLAIESGQEFTKVALKYNQDYDHPNGNFKWVSELDSPPSLPPAAFAQLKQLKENELSEPFQADGRTWMIIKYTKTKEYDAAEQLKEQKALEAIFSEKAQEIYKTWLTSMKDDAYIEILEDDLKTPELY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: surA mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0760O, under O: Posttranslational modification, protein turnover, chaperones
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].