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sucB

Victor ID 549
Gene Name sucB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190739
NCBI Protein GI 56707256
Locus Tag FTT0077
Protein Accession YP_169152.1
Other Database IDs UniProtKB-ID: Q5NIJ0_FRATT
UniRef100: UniRef100_A4IW37
UniRef90: UniRef90_A4IW37
UniRef50: UniRef50_B2SEZ4
UniParc: UPI000049C1C0
EMBL: AJ749949
EMBL-CDS: CAG44710.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG630916
OMA: MLTTYNE
ProtClustDB: CLSK986256
Taxonomy ID 177416
Gene Starting Position 80025
Gene Ending Position 81494
Gene Strand (Orientation) +
Protein Name dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex
DNA Sequence 
>gi|56707187:80025-81494 Francisella tularensis subsp. tularensis Schu 4, complete genome
GATGGTTGAATTAAAAGTACCTATGTTCCCAGAGTCTGTAGCAGATGGCACATTAGCTCAATGGAATAAA
AACGAAGGTGACTTTGTAAATGAGGGCGATATCTTGGCAGAGATTGAGACTGATAAAGTTGTTCTAGAAG
TACCTGCAACATCTAGTGGTGTTTTAAAAGGGATAAAAAAACATGCTGGTGATACAGTGCTTTCAGAAGA
GTCATTAGCGATCATTGATACTGCTGTTTCTACATCTGAACCTAACCAACAAACTACTAATCAAGGAAAT
GCTTCAGAAGCAACTGCTACTGGGCAAGAAATTGATATTAAGGCGCCTGTATTTCCAGAGTCTGTAGCAG
ATGGCACGATCTCAGAGTGGCATAAGAAAGAGGGTGAGGCTGTTTCTGAGGGTGATATCTTAGCAGAGAT
TGAGACTGATAAGGTTGTTCTAGAGGTTCCGGCAACATCAAATGGTGTTTTGACAAAAATATTAAAAACA
GCAGGAGAGACTGTACTATCTGCAGAGCTTATCGCTAAGATTACAGCAGGAGGCGCAACTGCTACTACGA
AATCAGAAGCTTCGGTGGGAGTTTCTCAAGCAAATAATGATCCGCATCTAGTACCTTCAGCACGTAAAGC
TTTTAATGCAAGCGGCTTGGATACTGCTGCTAATATCGAAGGTACAGGTAAAAAAGGGCGTATAACTTCT
GAAGATGTCAAAAAAGCAGTTGCATCAGTAAATAAACCTCAACAACAGACAGTTGTTATAAATCAAGGTG
CTAGATATGAAAAAAGAGTCAAGATGACTCGTCTGCGTCAGACTATAGCAAATAGGTTAGTTGAGGTTCA
ACATACTAATGCAATCTTAACTACTTTCAATGAAGTAGATATGAGTGCAGTTATGGAGCTTAGAAACAAA
TATAAAGATATGTTTGTCAAAGAACATGATACTAAGCTTGGCTTTATGTCTTTCTTTATCAAAGCAGCAA
CAGAAGCACTTAAGAAATTCCCAGATGTAAATGCCTCTATTGATGGTGATGAGATTGTTTACCATAATTA
TTTTGATATTGGTATTGCTGTAGGTACTGATAGGGGTCTAGTGGTACCTGTACTAAGAGATACAGATACT
AAATCTCTAGCTGAATTAGAAGCCGATGTTTTAGACAAAGCGATTAAAGGTCGTGATGGTAAATTAAGCC
TTGAAGATATGCAAGGTGGTACATTTACGATTACAAATGGCGGAACTTATGGTTCGATGTTATCTACGCC
TATTATTAATTCACCGCAAAGTGCTATTTTAGGTATGCATAATATTGTTGAGCGTCCTGTAGTTGTTAAG
GGTGAGATTAAGATTCGTCCAATTATGTATTTAGCGTTATCTTACGACCATAGAATCATTGATGGCGGTA
CATCTGTAAGATTCTTGAAGATGATCAAAGAGCTAATTGAAGATCCAAATAGAATTCTTCTACAAGTATA
Protein Sequence 
>gi|56707256|ref|YP_169152.1| dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex [Francisella tularensis subsp. tularensis SCHU S4] MVELKVPMFPESVADGTLAQWNKNEGDFVNEGDILAEIETDKVVLEVPATSSGVLKGIKKHAGDTVLSEESLAIIDTAVSTSEPNQQTTNQGNASEATATGQEIDIKAPVFPESVADGTISEWHKKEGEAVSEGDILAEIETDKVVLEVPATSNGVLTKILKTAGETVLSAELIAKITAGGATATTKSEASVGVSQANNDPHLVPSARKAFNASGLDTAANIEGTGKKGRITSEDVKKAVASVNKPQQQTVVINQGARYEKRVKMTRLRQTIANRLVEVQHTNAILTTFNEVDMSAVMELRNKYKDMFVKEHDTKLGFMSFFIKAATEALKKFPDVNASIDGDEIVYHNYFDIGIAVGTDRGLVVPVLRDTDTKSLAELEADVLDKAIKGRDGKLSLEDMQGGTFTITNGGTYGSMLSTPIINSPQSAILGMHNIVERPVVVKGEIKIRPIMYLALSYDHRIIDGGTSVRFLKMIKELIEDPNRILLQV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sucB mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0508C, under C: Energy production and conversion
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].