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sthA

Victor ID 547
Gene Name sthA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3190728
NCBI Protein GI 56707804
Locus Tag FTT0684c
Protein Accession YP_169700.1
Other Database IDs UniProtKB-ID: Q5NGZ2_FRATT
UniRef100: UniRef100_Q5NGZ2
UniRef90: UniRef90_A7NBY4
UniRef50: UniRef50_Q6LLT9
UniParc: UPI000049C35A
EMBL: AJ749949
EMBL-CDS: CAG45317.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG515043
OMA: EYFVENT
ProtClustDB: PRK05249
Taxonomy ID 177416
Gene Starting Position 700878
Gene Ending Position 702293
Gene Strand (Orientation) -
Protein Name soluble pyridine nucleotide transhydrogenase
DNA Sequence 
>gi|56707187:700878-702293 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATTATTGGTGTTCTGGGACAAATTGTTTATTTTTAGGTTTAAGCTTATTAAGACCGTCAATACCAGCAAT
ACGATAAGCCTCAGCCATAGTAGGGTAGTTAAATGTAGTGTTCAAAAAGTATCTGATAGTATTGTGTTTG
CCTGGCATTGATTTGATAGCTTGACCAATATGGATAATCTCAGATACCCTATGACCAAAACAGTGAATGC
CAAGGATCTCTAGAGTTTCTTTATGGAAAAGTATCTTTAACATCCCTGTTTCACTTCCTGAAATTTGTGC
ACGAGCTAAATCTTTAAAATATGCTCTACCAACTTCATATGGAATATTCTCAGCAGTTAATTGCTCTTCT
GTTTTTCCAATACAACTAATCTCAGGGCGGGTATAGATCCCTGTTGGGATATCCTCGACTAATTTGTCAT
TACAAGAGCCATCTATAATATGCGTAGCTGCAAATCTACCTTGGTTAAAAGCAGATGATGCAAGTGAAGG
AAAACCTATAACATCACCAACAGCATATATATTCTCTTGAGTAGTTTGATAATTGTCATTAACCTTAACA
AGACCTCTTTGTGGGTCATACTCAACTCCAATTTTATCTAAATTAAGGCCATTTGTATTACCTGATCGGC
CAAGCGCAAACAAGACATAATCAGATTCGATAATTCTACCTGAGTTAAGAGTAGTAACTACTTTATCTCC
TCTTGCTTTGATGCTTTTATAAGTTTCATTATGTATTAGATTAATTCTTTGATTAACTGTAAAGTGATTT
GTTAGCGTTTCGATAATTTCATCATCAAGGAACGACATTAGTTTATTTCTAGTGTTGATAAGATTTACCT
GAATATCTAGTGTTCCAAGTATGGATGCATATTCACAACCAATTACACCAGCACCATAAATAGTAATTGA
TTTGATATTTTTGTCTTTCAACTCTAGAAGCTTATCACTATCCAAAATTCTAGGATGAGTAAAGTCAATA
TCATCAGGATGATATGGACGAGATCCTGTAGAGAGAATGAATTTTTTTGCCGTAATGATTTCAGTTGAAC
CATTTTTACGTGAAATTTTTATTTTATGCTTGTCGATAAAACTAGCAAAACCATAGAAAACATCAATTTC
ATTATTAGCGAAACGATTTCTCTTAATCTCTCTTTGTTTGATAACTATTTCATAAGCAGTATCAAGCATC
TCTGGGAAATCGAAATTCTTCTTGTTGTGCCAAACTTCACGTGATAGCTGTCTTAGAGCTTTACTTGGAA
TTGTTCCCCAGTTATTACAACCACCACCAATAGCGTCATCTTCGATGATAGCTACTTTTTGTCCGTTCCT
AGTTGCTTTCATCGCAGCCCCTTCACCACCAGGACCACTGCCTATAATAATAATATCGTAATTATATTCC
ATGGTTTTACTCCACA
Protein Sequence 
>gi|56707804|ref|YP_169700.1| soluble pyridine nucleotide transhydrogenase [Francisella tularensis subsp. tularensis SCHU S4] MWSKTMEYNYDIIIIGSGPGGEGAAMKATRNGQKVAIIEDDAIGGGCNNWGTIPSKALRQLSREVWHNKKNFDFPEMLDTAYEIVIKQREIKRNRFANNEIDVFYGFASFIDKHKIKISRKNGSTEIITAKKFILSTGSRPYHPDDIDFTHPRILDSDKLLELKDKNIKSITIYGAGVIGCEYASILGTLDIQVNLINTRNKLMSFLDDEIIETLTNHFTVNQRINLIHNETYKSIKARGDKVVTTLNSGRIIESDYVLFALGRSGNTNGLNLDKIGVEYDPQRGLVKVNDNYQTTQENIYAVGDVIGFPSLASSAFNQGRFAATHIIDGSCNDKLVEDIPTGIYTRPEISCIGKTEEQLTAENIPYEVGRAYFKDLARAQISGSETGMLKILFHKETLEILGIHCFGHRVSEIIHIGQAIKSMPGKHNTIRYFLNTTFNYPTMAEAYRIAGIDGLNKLKPKNKQFVPEHQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a sthA mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG1249C, under C: Energy production and conversion
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].