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lmo0317

Victor ID 542
Gene Name lmo0317
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 987534
NCBI Protein GI 16802362
Locus Tag lmo0317
Protein Accession NP_463847.1
Other Database IDs UniProtKB-ID: Q8YA45_LISMO
UniRef100: UniRef100_Q8YA45
UniRef90: UniRef90_A0AFC4
UniRef50: UniRef50_B4RNJ4
UniParc: UPI00000550A8
EMBL: AL591974
EMBL-CDS: CAD00844.1
RefSeq_NT: NC_003210.1
HSSP: P55882
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0317
GenoList: LMO0317
HOGENOM: HBG476673
OMA: LNIGHGH
ProtClustDB: CLSK563870
BioCyc: LMON169963:LMO0317-MONOMER
Taxonomy ID 169963
Gene Starting Position 341750
Gene Ending Position 342553
Gene Strand (Orientation) +
Protein Name similar to phosphomethylpyrimidine kinase (ThiD)
DNA Sequence 
>gi|16802048:341750-342553 Listeria monocytogenes EGD-e, complete genome
AATGACTTTTCCACAAGTGTTAACGATAGCTGGTTCGGATTCAGGTGGTGGTGCGGGGATACAAGCGGAT
ATCAAGACATTTCAAGAGCGCAGAACATTTGGCATGTCTGTGATCACGGCGATTACGGCGCAAAACACAC
TAGGGGTAAAAGCGGTGCATAAAATCCCGGTAGAAATGATTCGCGAACAGTGCGATGCGATTGCAGAGGA
TTTTCAAGTGAGCGCCGTGAAAACGGGCATGCTTGCGGATGCAGAAATTATCCGGGAAGTGGTGCGGAAT
ATACGTTTGCACAACTTCCCAAATCTCGTCATTGATCCCGTGATGATTGCGAAAGGCGGCACGGCTTTGC
TTGAAAACGAAGCAACACAGGTTTTGAAAGATGAACTTTTACCGCTTGGTACGATTATTACGCCGAATAT
TCCAGAAGCCGAAGAAATTCTCGGAGAAAAAATCACAACGAAGGCTGAAATTGAACGAGCAGCTAAGAAA
ATCTATGATATGGGTGTAAAAGCAGTTGTAATTAAAGGTGGGCATAGCGAAATGACGGAAGCAGCTGATT
TTTATTTCGATGGGGTAACGGCGAAATGGCTTACGAGCGAGCGCTTTGATACGCCACATACGCACGGGAC
TGGTTGCACTTTTTCGGCATGTATTGCAGCTGAACTTGCGAAGGGGAATTCGCTTTTGGATAGTGTCATG
GTTGCGAAAGAATTTATCTCAAGTGCGATTAAATATCCGCTTGGAATTGGTCACGGTCATGGTCCAACCA
ACCATTTTGCTTACCGAATGGAGGATGGGAAATG
Protein Sequence 
>gi|16802362|ref|NP_463847.1| phosphomethylpyrimidine kinase [Listeria monocytogenes EGD-e] MTFPQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPVEMIREQCDAIAEDFQVSAVKTGMLADAEIIREVVRNIRLHNFPNLVIDPVMIAKGGTALLENEATQVLKDELLPLGTIITPNIPEAEEILGEKITTKAEIERAAKKIYDMGVKAVVIKGGHSEMTEAADFYFDGVTAKWLTSERFDTPHTHGTGCTFSACIAAELAKGNSLLDSVMVAKEFISSAIKYPLGIGHGHGPTNHFAYRMEDGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: knockout inhibited growth in mMWB and reduced spread in epithelial cells (Schauer et al., 2009).
COG COG0351H, under H: Coenzyme transport and metabolism
References
Schauer et al., 2009: Schauer K, Stolz J, Scherer S, Fuchs TM. Both thiamine uptake and biosynthesis of thiamine precursors are required for intracellular replication of Listeria monocytogenes. Journal of bacteriology. 2009; 191(7); 2218-2227. [PubMed: 19181806].