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YPD1

Victor ID 5392
Gene Name YPD1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23889385
NCBI Protein GI 799345490
Locus Tag CNAG_06151
Genbank Accession CP003831
Protein Accession XP_012053169
Taxonomy ID 235443
Chromosome No 12
Gene Starting Position 438508
Gene Ending Position 440101
Gene Strand (Orientation) +
Protein pI 4.09
Protein Weight 22754.2
Protein Length 209
DNA Sequence 
>gi|799350913:438508-440101 Cryptococcus neoformans var. grubii H99 chromosome 12, complete sequence
TTGTGCACCGGTGCTGTCCCATACTCCCATACAACCGTCCCTTCTCCCCCCTTGCCTCGTATCCCCCACC
TGGGCCCCTTGCACGCCTTTGCACCGCCTCCACCAGCCCACCATGCCAGACCAGGCCAGATCGCCGTCAG
CCCCCGCCACTACCTCGAACATCAGCGACCGCCAACATACGCAGCCGCAACCCGCTAAAGATGACAAATC
TCAGCAGGCAGACGTAAAGTCGCCAGAGTCAAGTCGGGAGCAGAGTGAACAGGTCGAGGAGGAGGCTGCG
GCCGAAGCGGACGACGAGTCGGACGACGAGGAGCCAGAGGTGGGTCGCGATTGCCTGACCGTTTTTGTGC
CTCGTGTCGGAAGTGTGTAGCCGTAGCCGGGTGTGTGCTGACCGCCGTGTCTTCCCCTCGCGCCTCCTTC
CTTCCTCTCCAATGCCCATCCTCCGCAACCTGCCACTTGGCATTGTGCATTCTCCGTCTCTCATTCGCCC
GTCGCGCCGCTTTCCGCCGCCGTTCCTGGCTATCGACAGACCGGCGATGAAATCATCGACATGGAAACGT
TCCAGCAAATCATGGACATGGACGAGGAAGACGAGGTGGACGAAGACAGTGATGAAAAGCATTCATTCTC
AAAGGGTATCGTGTGGGGATACTTTACTCAGGCAGAAGAGACGTTCAAGGATATGGAAGATGCTCTGTGC
GTATTTTCGATTATTTTTCGTCTGCTGATCACAATTGGAACGGCCACTGACGCGTGTTGCATTTTGTCTC
ATTGTTGTTCCACTATCCATACACGAAATAAAACGAACCCACATTACACCCAACCCGCCCATACAGCTCC
CGTAAAGACCTTTCCAAACTCTCCTCTCTCGGCCACTTTCTCAAAGGCTCGTCTGCGGCACTTGGTATCA
TCAAAGTCCAAGCCTCTTGTGAAAAGATGCAGCACTATGGCAATCTTCGCGACGAAGAAGCCGGTGCCGA
TCTCGATGATGCCGAGGCACTCAAGCGGATCGACGCGTTATTGGTCAAGTGCAAGAAGGATTACAAGGCG
GCTAAGAACTGGATGGTCAAGATGTACGATGATCTCAAGTAAGAGAGACGGTTTAGAATAATAACAGACA
GGGGCAAGTCGGCCATTGTAGCTTGTAGTAATGCGTTTTTTGGTGAGAGGGAGGGGATTTATCCTCTGCC
TCTTTTTTTAAATCTTTCTTTCGACCTCTATAACTTGTGGATTTATCGTGCCGACTCGTTTTTGTTTATA
TCTACCCACCCCGTTATCTTTTTCACCTTTAACACCACTTCCCCTCTCGTTTTCATGCCTCAATCCTTAA
TCGCGTTCTTTCTATACATACTTTTCTACAACTGTTTAAAGCACGTGTAGCACCATCGTTCTCTTTGTCT
TTTGTTAGCAATTCCCCCCTACCACCACCACGCACGGGCCCCGGCAGCGTGACGTTTAAGAAGAGAATGT
AGTAGAGGAGGTAGATGATGTGAAGGAAAAAAAGAAAAAGTACGAGAAGGAATGGTAAATATCATATTTG
TGCATTTTACGTTTTATTTGTCTTTTAAATGCAGTACAGAATTTTGGTTCTTCA
Protein Sequence 
>gi|799345490|ref|XP_012053169.1| osomolarity two-component system, phosphorelay intermediate protein YPD1 [Cryptococcus neoformans var. grubii H99]
MPDQARSPSAPATTSNISDRQHTQPQPAKDDKSQQADVKSPESSREQSEQVEEEAAAEADDESDDEEPET
GDEIIDMETFQQIMDMDEEDEVDEDSDEKHSFSKGIVWGYFTQAEETFKDMEDALSRKDLSKLSSLGHFL
KGSSAALGIIKVQASCEKMQHYGNLRDEEAGADLDDAEALKRIDALLVKCKKDYKAAKNWMVKMYDDLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Ypd1 is required for the viability of C. neoformans via the Hog1 mitogen-activated protein kinase (MAPK) pathway but plays multiple cellular roles in both a Hog1-dependent and -independent manner (Lee et al., 2011).
References
Lee et al., 2011: Lee JW, Ko YJ, Kim SY, Bahn YS. Multiple roles of Ypd1 phosphotransfer protein in viability, stress response, and virulence factor regulation in Cryptococcus neoformans. Eukaryotic cell. 2011; 10(7); 998-991002. [PubMed: 21642509 ].