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clpP from Listeria monocytogenes EGD-e

Victor ID 539
Gene Name clpP from Listeria monocytogenes EGD-e
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 987364
NCBI Protein GI 16804506
Locus Tag lmo2468
Protein Accession NP_465991.1
Other Database IDs UniProtKB-ID: CLPP_LISMO
UniRef100: UniRef100_Q71WV9
UniRef90: UniRef90_Q71WV9
UniRef50: UniRef50_Q8YQX8
UniParc: UPI00000556F3
EMBL: AF102775
EMBL: AL591983
EMBL-CDS: AAF04744.1
EMBL-CDS: CAD00546.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo2468
GenoList: LMO2468
HOGENOM: HBG558421
OMA: SPMEAQD
ProtClustDB: PRK00277
BioCyc: LMON169963:LMO2468-MONOMER
Taxonomy ID 169963
Gene Starting Position 2542013
Gene Ending Position 2542609
Gene Strand (Orientation) +
Protein Name ATP-dependent Clp protease proteolytic subunit
DNA Sequence 
>gi|16802048:2542013-2542609 Listeria monocytogenes EGD-e, complete genome
TATGAACTTAATTCCAACAGTAATTGAACAAACTAGCCGCGGTGAACGTGCATATGACATTTATTCCCGT
TTATTAAAAGACAGAATTATTATGTTAGGATCTGCAATTGATGACAACGTGGCGAATTCCATCGTTTCTC
AATTATTATTCTTAGATGCACAAGATCCTGAAAAAGATATTTTCCTGTACATCAATTCTCCAGGTGGAAG
TATTTCAGCTGGTATGGCCATTTACGATACAATGAATTTCGTTAAAGCGGACGTACAAACAATCGGCATG
GGTATGGCAGCTTCCATGGGCTCATTCTTACTAACAGCTGGTGCAAATGGCAAACGTTTTGCCTTGCCAA
ACGCTGAAATTATGATTCACCAACCACTTGGCGGTGCTCAAGGTCAAGCAACTGAAATCGAGATCGCTGC
TCGCCACATTTTAAAAATCAAAGAACGTATGAATACGATTATGGCTGAGAAAACTGGTCAACCATATGAA
GTCATTGCTCGCGATACAGATCGTGATAATTTCATGACTGCACAAGAAGCAAAAGATTACGGCTTAATTG
ATGATATTATCATTAATAAATCTGGCTTAAAAGGCTA
Protein Sequence 
>gi|16804506|ref|NP_465991.1| ATP-dependent Clp protease proteolytic subunit [Listeria monocytogenes EGD-e] MNLIPTVIEQTSRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLDAQDPEKDIFLYINSPGGSISAGMAIYDTMNFVKADVQTIGMGMAASMGSFLLTAGANGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILKIKERMNTIMAEKTGQPYEVIARDTDRDNFMTAQEAKDYGLIDDIIINKSGLKG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and attenuated virulence in mice (Gaillot et al., 2000).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Gaillot et al., 2000: Gaillot O, Pellegrini E, Bregenholt S, Nair S, Berche P. The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes. Molecular microbiology. 2000; 35(6); 1286-1294. [PubMed: 10760131].