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Sxi1alpha

Victor ID 5374
Gene Name Sxi1alpha
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23889981
NCBI Protein GI 799328572
Locus Tag CNAG_06814
Genbank Accession CP003824
Protein Accession XP_012049563
Taxonomy ID 235443
Chromosome No 5
Gene Starting Position 185699
Gene Ending Position 188858
Gene Strand (Orientation) +
Protein pI 8.7
Protein Weight 43265.02
Protein Length 405
DNA Sequence 
>gi|799350697:185699-188858 Cryptococcus neoformans var. grubii H99 chromosome 5, complete sequence
TTTTAGAGAACAATAGGGCATACTGCATGTGTATGTGGTTTCAAATCAACAGGGCAACCCCGGCTCACCA
TCATTTCTTATTGTTCTGCAGCGGTCTCTGCGCTGCAAATTAATATTCACGGACTAGGGGACGGTTCAAA
AAGGCATATTATTTTGTCTTCATATATATATGCTTGATGCCCATACGCAATAGTGTACGTTTAAGGATAT
TTCTTTTTACCATTGCCACCTTTCCCTTTATATACCATCGCGCATATCAGCCAACAAACAATAAGCAGCT
GATCAAATAATGCTTTCGACCTCTGATAGTTCTTCCCAATCTATCCAAAGGTCTCTTCAGGACGATCTTC
TGGATTTTCAAGAGACATTCACCCAACCCCTAGGGAAAAGTGAAGTTCATGACCTCGAGAGCGTCGTCCG
AAAAGGGAGCAATTTGGTAACAGCCATTAAGTGGAGCTCTTCTCATGATTTACTGGACGAAAATACCGCG
AGCTTGGCGTACGCTGTGGCCCGCAGTGTGAAGCTCATTGGTTCTTCGGCCTTAAAACTTGAACAGGGTT
GGGAAGATGCGGTCGGAGAAGCAATACTTAGAATAGAGTCACTTTTGCCAGATGAAGGTGAGTTCAAATC
TTTCAAGATCTTAGTATGCGAGCTCAATTAGTTTAACTAAGGGCAAAGTCGAAAACGTCGCCAGAGGAAC
CATGAGCCACGGCCGAAACGATATTGCCGCGGTCCCTCTTCCGAGTCATGCCTTGCGTGGCCCGAATCCA
CTTTCGGCAATTCACCAAAGCCCTCAGAGTCTGCAACTGACCATACCGTCGTCCGCCTCTGGTTCCTTGA
TAACCTTGCTTATCCCTATCCAACCGCACAACAGAAAGACTTTCTCGCCAAAACTGCTGGCATCCAGCGC
AGCCAAGTCGATTCTGATCTGACTAATTACCGTCGCCGGGCTGGATGGACTGACATCATGAATATGTGGT
GTGGTGGCGATCGCAGCGCGATGAAAAAATTGATGGAGAGGGTGGAGAGAGGTAAGGAACAAAGGAAGAA
GATTCTGGATGCCGTGCAAGGGTGTAGAGATTATTTGACGATGAAGGAGAACAATAAGATCGGTGACTGG
GTCAAAGAGGTTAGTGCTCTCATCATTGCCTCTTGAAGTTCCCCAATATTTCGGGCTCACCTGCCGCTTG
CCGCGACCATCCGCTAACAGACCTCATAGATCACTCAGAACTCCACCTCCAAATACCGCTTCACTGGATT
CCTCCCCGACATGTCCGCCGCCTCTCCATGCTCTGGAATTCGACCCAGCACTCCCCGTTCCTTCTCCGGT
AGTAGTGCCATCTCTAGCATGTCATCTTGTTCCGAAGTCTCCGAGGCTTCTGCCATCATCCCTATTCCTA
GAAAAAGATGTTATACCGACGACGAGCCCATTTCCCCCTTGAAACGCGCTCGAAATCATACTGTTGGGGT
TTCCGGTCCTTACGAGTCTTGGTCCTTCGCCGACCTGCAGCCTATGCCTCCTTCTCCGGGTGCCGCCCAA
GAGAACACCGCCAACGATTCTGTCGCCCCCACCACTTACTTTATCAGCGCAGCTTCTCGCTCATTACCTT
CATCTGCCGAAACCCGTACCAAGCGACGCCTATCGTGTTAATACATATACACCATGCATCTGCGCAAACG
CACTCATGATGGTCGAGGCCCCAAGTATGGGAGTTCAACCCGCTCCTGTAAGGTGTTTTTTTCCGCCTAG
ACCTGATTGAGTGTAAGCCTTTTAAGGCAGTCGTACCCGAAGATGAGAGAAGACTGAGTGGTAGATTGCA
CGAATGAATGAGACAGAGATGAGGATGCGAAGAGGATAAAGGTGATCTTGATTGTGGAGTTGTTGGTTTC
GCATACTGGTACCCACCGAAAAGAATGTACCCCCCCCCTCTTTTGATCCCGCGACGCGTTTTTGACTCTA
CCCCATAACTATGATCTTGAATTGTTCATGCATGTACTTATAACTATCTGATTATTTTCCATAGTAGCAC
CCCAGGCCACCCCCACTACCAAACGAACTGTTATGGAAGCCCACAAAAGTGGGAAATCATTCAGCAATCT
TGCAAAACAATATAAGCGTCCCAAGGGTACAATCAAGCGCTGGTGTCGAGAGTATGCGCACCGTGAACAC
ACTTATCCGCTCCCAATCCCTGGAAGGCCAAGGGTGTTGGATCAGGGGCAAGTAAGGAATCTTCTGAGGG
ACTTTATTCGCAGTCCGCGTGAACCCGGGAGTGTTCACGCGAAGAGATACAATGTCGGCGTGACAACTAT
CGTCAGGATCGCTCATGAGCATGGGTTTTACCGCAGAATTATGAGGCGTAAGCCTTATCTTTCGCCCAAA
ACTGTGGCTAAAAGGAAAGAGTGGGCCAGGAACAACATGAAGAGGGACTGGCGGGACGTTGTTTTCACTG
ATGAATGTGCACTGGAGCTGGGGGGACAAGTACGAGGCGGCCAAGGACTACCCGGCGCGCAGGCGAAGCG
TACGCTCCACAACACATCCTACCAACCTTCCATTCTGGTCGACAGAGCCTGATGGTTTGGGGAGCGATTA
GCTACTACCAAAAATTCTCTCTTTTACGCCTTCCTCTAGCTCCATCGACGGTCAAAAATGGCGTCAGGTC
TAAGGCCGAGTCCCTCAACGGGCTTAGGTACACCGAGATGGTGGTCAAAGGCGTCTTGGGGGGCGAGGGT
GGTATCCTTAGGTCGCTGAGGTCTTCCGGTTTCGAAAATATCCTTGTGTTGGAGGATGGAGCTCCCTCGC
ATTGCGCTGCTGTTGCGAAAGCAGCGAGAGCGGAAATGGGGATTGAAACCCTCGACCATCCCGCTCCTCT
CCCGAGCTAAATCGCATAGAGAACGCATGGTATCCCCTAAAGTCAAAGGTCGCGGCTTTCCCCAGAGTCG
CTACGTCGCTTGACGAGCTCTGGGAGCAAATACAGAAAGCATGGGATGAGATAGACCTGTAGCAGGTCCG
GGATCTGATAGATGAGATGGAGCAGAGGCGTGTAGCGGTGTGGAAAGCCCAAGGGAAGTCTACCAAGTAC
TAGATTATTGTAAATTATACATAGAATCTGCCTATGTACTTGGATTTCCCGAAAACATGCATTGTAAAAT
GATAAATGCA
Protein Sequence 
>gi|799328572|ref|XP_012049563.1| hypothetical protein CNAG_06814 [Cryptococcus neoformans var. grubii H99]
MLSTSDSSSQSIQRSLQDDLLDFQETFTQPLGKSEVHDLESVVRKGSNLVTAIKWSSSHDLLDENTASLA
YAVARSVKLIGSSALKLEQGWEDAVGEAILRIESLLPDEGQSRKRRQRNHEPRPKRYCRGPSSESCLAWP
ESTFGNSPKPSESATDHTVVRLWFLDNLAYPYPTAQQKDFLAKTAGIQRSQVDSDLTNYRRRAGWTDIMN
MWCGGDRSAMKKLMERVERGKEQRKKILDAVQGCRDYLTMKENNKIGDWVKEITQNSTSKYRFTGFLPDM
SAASPCSGIRPSTPRSFSGSSAISSMSSCSEVSEASAIIPIPRKRCYTDDEPISPLKRARNHTVGVSGPY
ESWSFADLQPMPPSPGAAQENTANDSVAPTTYFISAASRSLPSSAETRTKRRLSC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SXI1alpha establishes alpha cell identity and controls progression through the sexual cycle. Ectopic expression of SXI1alpha in a cells is sufficient to drive a/alpha sexual development (Hull et al., 2002).
References
Hull et al., 2002: Hull CM, Davidson RC, Heitman J. Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. Genes & development. 2002; 16(23); 3046-3060. [PubMed: 12464634 ].