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RAS2

Victor ID 5354
Gene Name RAS2
Sequence Strain (Species/Organism) Cryptococcus gattii WM276
NCBI Gene ID 10186290
NCBI Protein GI 321262879
Locus Tag CGB_I2550C
Genbank Accession CP000294
Protein Accession XP_003196158
Taxonomy ID 367775
Chromosome No I
Gene Starting Position 543332
Gene Ending Position 544297
Gene Strand (Orientation) -
Protein pI 7.86
Protein Weight 22995.22
Protein Length 232
DNA Sequence 
>gi|321263212:543332-544297 Cryptococcus gattii WM276 chromosome I, complete sequence
CCTAGAGCACCACACACTTGTGCTTCTTCTTCCTTTTCCCACCTATCCTTTCTGTCGGCATCACCGACTC
TTCACCTGCACCACCTTGTCTCCCCAACTTGATCTTCTTGACCAAACACTTGAACGCGGCCTCTACATTA
CTATTCGTCTTGGCGCTCACTTCAAAGAATTCACAGCCTAGCCGTTTGGCCAAACTGGCCCCTTCATCCG
TTGATACTTCTCTGGAATGGAACATGTCCTTCTTGTTCCCCACAATCACGATCGGTACCCGTGCTGCCCA
CATCCCGCTCCCGCTCCCGCCCCCGCCCCTACTTCCACTTCCACTCCCATCTGTTGTTGATAAGCCATAG
GGGTTGGAAGACGACGAAGGGAGGGGTAAACCCGATTCATCCTTGACGCGAAGGACTCGCTCGACTACAT
GCTCGACACGTTCAAATGTCGGTCGAGAGGTTATAGAGTACACGATCAGGAATCCTTCGCCTTCACGTAT
CCATTGGTCGCGCAGTGCCGTGTATTCCTCTACCCCCCAAAAAGTCAACGCAGTTTTGGGTCAACTCAAT
TATTAAATGATGATGATGATGATGATGGGTGGTAAGGGAACAAGACGAAAAGACGTACCTTGTCCAGCAG
TATCCAGAACTTCAAGTAAACAGGGCTGATCGTCTACAACCCATTGTTTGCGGTAACAATCTTCAATGGT
AGGATCGTATGTCTAAACAAGTTGTCTCTGGTTAGCATGTAAAATACCGTATACCTTGCCCGAGCGTTTC
TTGTAAAGGAGAAGGAGAAAAGAGAACCAACCTCGACGAAAGAAGACATGGTAAACTATTCCTCAGCAGT
CAGCTTTTCATTTTTTTCTTTTTTTCAAGAGGTAAGGTAAGGGAGGGGGGGGGGCGAAACTCACTTGGAC
TGTTATGGCAGTCTTACCGACACCTCCGTCGCCGAGGACAGTTATCTTAAAGAGCA
Protein Sequence 
>gi|321262879|ref|XP_003196158.1| ras2 protein [Cryptococcus gattii WM276]
MLFKITVLGDGGVGKTAITVQFTMSSFVETYDPTIEDCYRKQWVVDDQPCLLEVLDTAGQEEYTALRDQW
IREGEGFLIVYSITSRPTFERVEHVVERVLRVKDESGLPLPSSSSNPYGLSTTDGSGSGSRGGGGSGSGM
WAARVPIVIVGNKKDMFHSREVSTDEGASLAKRLGCEFFEVSAKTNSNVEAAFKCLVKKIKLGRQGGAGE
ESVMPTERIGGKRKKKHKCVVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The Ras1 signal transduction pathway controls the ability of the pathogenic fungus Cryptococcus neoformans to grow at high temperatures and to mate (Wang et al., 2002).
References
Wang et al., 2002: Wang P, Nichols CB, Lengeler KB, Cardenas ME, Cox GM, Perfect JR, Heitman J. Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. Eukaryotic cell. 2002; 1(2); 257-272. [PubMed: 12455960].