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RAC1

Victor ID 5353
Gene Name RAC1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23889257
NCBI Protein GI 799344608
Locus Tag CNAG_05998
Genbank Accession CP003831
Protein Accession XP_012052960
Taxonomy ID 235443
Chromosome No 12
Gene Starting Position 43518
Gene Ending Position 45666
Gene Strand (Orientation) +
Protein pI 9.21
Protein Weight 20477.97
Protein Length 199
DNA Sequence 
>gi|799350913:43518-45666 Cryptococcus neoformans var. grubii H99 chromosome 12, complete sequence
CGCGTACAACGGGGTAACGACACACTCCCCCCTCGACCTGCCTGAAACAGCCCCGAACGGGATTCGCGGC
ATAGCGCAACAGCCCAGGATGGCCATGCAGAGTATCAAATGTACGTCTTTCCTTTCTCACGCCGCCCAGC
TCCTAACTCTGCCGCCCAGGCGTCGTCGTCGGTGACGGTGCCGTCGGAAAGGTATATATCATCCCATTCC
CTCTCAATCCACTACGCCATACTAACAGCGACGATCGCGAGGATAGACATGTCTCTTGATTTCATACACC
ACCAACTCTTTTCCCGGGGAATACGTCCCTACTGTGTTTGACAACTACTCTGCCAGCGTACTCGTTGATG
GTCGGCCAGTCAGTTTGGGATTATGGGATACTGCCGGACAGGAAGACTATGAGTGGGTCTTTTTTTTCTG
TTCTCCTCTTCTACTTCTATACCTATTTACTCCTGTCTCCCATTATCCTTTTGAACTCCCCTTCATATTT
GACACGCGAACAAAAAGTGGCTGACACCATCCGCCATTTCACTTGAAATAGCCGGCTAAGACCACTATCC
TACCCACAGACCGACGTATTCCTCGTCTGTTTCTCAATCGTCTCCCCACCAAGTTTCGAAAATGTCAAAA
CTGTACGTCAATGGAGTCTTGGATTTATGGATTCTGGAGGAATCAGGCGTGCCAGGAACCGCTTTTCATT
CAAAAGAGCAATCAAGAGCTGACCATTTTCCCGCTTTGTCGATCTTTGATCTTTGCATTTATAAATCATT
GTTAAAAAAAAAAAACGTTTTGGAAAATAGAAAGTAAATCTTTCCCGTGCTCTCGCCCTCCCCTGCGCTG
CTCCACGCTAATACCCTCTCGCGCACCCGCCAGTGGATCCCCGAAATCCGGCACCACGCTCCAACTACCC
CCATCCTTCTGATCGGCACCAAACTCGATCTCCGAGACGACCCTGTCACCCTCTCTCGTCTGAAAGAACG
TCGTTTCCAACCGATCGGGTTTGAGATGGGTGTCAGATGTGCGAGGGAGATTGGGGCTGTTAGGTATTTG
GAGGCTTCTAGTCGGACGTACGTTTTTGTCTCCTTCTTCTTCCCATCCTCTGCTTTCCGCTGATGTGCGA
GTTTGTTGAACAACAACAACAACAACAACAAAAAAAAACAGGCAAAAAGGCTTGAAAAATGTATTCGACG
AAGCGATCCGTGCGGTACTCAGTCCCTCTGCAAGGGACGCAAGGGAGAAGAAGAAGAAGAAACAGCAGTG
TTTGATTCTCTGAGCAATGCCAAATGAGGCATTTAACTAGTAGGGTGCGAGGGCCACAAGGTGCGAGAGA
CGGGTGCGGACGACATTTAGATTTAGATGTTGGTGGTTAATGGGAGTTGATAGGGAGGGAAGGGCAAAAA
TGAGAAGCCGAAAGGTTGGAAAGAAGATATCACTAAAAAAAGGAAAAGAAAAAGGAACTGCCCCCAAGTT
GACCACAAAAACCAAGCACGGATCGGGATCACGAGGGGATAGCCTATTTTGTCGCATCTTTTTAGATTCA
TCGATTGATCAAGTTTTTATCTTTTTTTCCCATGCAAGCGTTGTATTTTTAGTTTACCCCTCTTACCCCG
TGGCCTACAATGTAATGGCTGTTAAATTTTGCGCGTTTCACTGCCCCCTCTGCAACTTTTGTTCGTCTCG
TCCAAGTTGCTTCATTTCCGGTTCGCATGTCAAGTCTCGTATTCATGTCATTGTGCTCTAATTAAATGCT
GATGTTTCGCCCTACTCGCCCACGCGCCCACATACATCCTCGCTTCCATAATCTCGCGATACCTGTGCCC
AAAGCTGCCGATTTACTGCCTCTTGACCTTTACCTTCATCCTGTCTGAAGCGCCCCTGACCTTTTCCCTC
CCGTGCGATGCTGCGCGCGTTAAGCCGCCCTGTTTATTGCGTGTCACGAGGCGAGGTGAGAAAGTTATGA
AGAAGGGGCAAAAGAGGAAGCAAAGTTACAAAGGGGTAAAAGAGGGAGGATGAGACGGTATTCGATAAGA
AATGTCAACGCCCGTACTCGGAGAATGGAAAAAAACAACAAACGCACCTTGCCAACCCACCCCCTCTTGG
TCAACCACCCGACAAACTTTGGCGTCCAGGCGACGGTCAGGCCTGCTCT
Protein Sequence 
>gi|799344608|ref|XP_012052960.1| rho family protein [Cryptococcus neoformans var. grubii H99]
MAMQSIKCVVVGDGAVGKTCLLISYTTNSFPGEYVPTVFDNYSASVLVDGRPVSLGLWDTAGQEDYDRLR
PLSYPQTDVFLVCFSIVSPPSFENVKTKWIPEIRHHAPTTPILLIGTKLDLRDDPVTLSRLKERRFQPIG
FEMGVRCAREIGAVRYLEASSRTQKGLKNVFDEAIRAVLSPSARDAREKKKKKQQCLIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The Rac paralogs play a primary role in polarized growth via the organization of reactive oxygen species and play only a minor role in the organization of actin (Ballou et al., 2013).
References
Ballou et al., 2013: Ballou ER, Selvig K, Narloch JL, Nichols CB, Alspaugh JA. Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans. Fungal genetics and biology : FG & B. 2013; 57; 58-75. [PubMed: 23748012].