Victors

PEX6
Victor ID	5343
Gene Name	PEX6
Sequence Strain (Species/Organism)	Cryptococcus neoformans var. grubii H99
NCBI Gene ID	23887613
NCBI Protein GI	799337413
Locus Tag	CNAG_04174
Genbank Accession	CP003828
Protein Accession	XP_012051430
Taxonomy ID	235443
Chromosome No	9
Gene Starting Position	195933
Gene Ending Position	200177
Gene Strand (Orientation)	-
Protein pI	4.98
Protein Weight	122467.88
Protein Length	1201
DNA Sequence	>gi\|799350821:195933-200177 Cryptococcus neoformans var. grubii H99 chromosome 9, complete sequence TTATGAGTAATCACTGTATTGCATCATCATCATCATTAATTCATCTGACAGACCATGTCTAAATCTCTAC AATTATATTTAGCTACAAAAAGTCCATTTAAGAAGCTTCTCATCCTTCAGCTTCGCCATTAACAACGACT GCTTTTCCCTTTCCCTTTCCTTTATCTTTCACTTCCTTCACATCGTCCTTCTTCCCAATTGCATACCCCT GAAATTCTTTTTGTACCCTCTCATAATGCTTCAGCTCTTCCTCGCTCACACTTGGAACCAGCTTGATCAA CGCTTCTTCAAAATCTTGCTGCCTTACCACCACCTCGGTCTCCTCCTTGGTCGCTATCTTCGCCAAGTAG TACTGCGGTGTCAATTCTCCCGGCCAAGTTTTAAGAGAAGGGTCTTCTTCCATAGACACCGAAGCATTTA GCTTGGCGATAGTACGATCCACCGCCTCTGCTTGCCGTGTCATAGCTCCCAGCATTGCATCCGCACATAG CGCATACAGGTCCGCACCCGTATAATTGAAGGGACACTGCTCTGCAATCTTTTCTATATCCAGATTTGGA TGGAGATTAAACTTGCGCGTGAGTGCTGTTAGGATACTTGCTTGGGCGGTATGGGTTGTAGGGATAGAGA GGTAGAGCATCTTGTCAAATCGACCTGGTCGGAGTAAAGCGGGGTCGAGCAAGTCTGGTCTATTTGTCGC ACCCATCACAAACACCCCTCCACGACTAGAGGACATACCATCGAGCTCTGCCAACAGCTGGCTCACTATC CGATCCATCACGCCACCTGAATCGCCCTGATTGCCTCTCTTGGGTGCTATAGAGTCGAGCTCGTCCATAA AGATGACACAGGGGGCTGCATCTCTTGCGCGTTGGAAAATGCGGCGAACATTGGCCTCGGATTCACCGAT GTACATATTCAGTAACTCGGGACCCTTGACGGAGAAGAAGTTGAGAGAGAAAGATGTGGCGACTGCTTTG GCAAGGAGAGTCTTACCAGTACCCGGTGGACCGTAAAGTAGTATACCTGTAACATACACATCAGCATAGG GCCCTGGTCAATAAATTATGTTAAAAGACTTACCAGAACGCTTCTTAAGACCTTCCCCAAACATCTCAGG CCTTTCCAAAGGCAGCTGGATTGTGTCCAAAATATCCTGCTTGACACTGACCAATCCACCCACATCATCC CATGACACATTCGGTATCTTGGGTGCACCTATGCTATCCGAATACGCCGCACGTGTCTTGGAGAGAGCAT GCGTAAAGTCCTCATCAGTGATAGATATCCCTGCTTGCTGGGCCTGGGGGAAGGATACACATGAAGAAGT AGAGCGCTTGACGGCCGCATTCCATGCCAGGTGGACGAATGAGTCAATATCTCCCGCGTTCAAAGCTGCG GTCTGTCTCGCAAGAGCTCTGACATCCACATCAGGGGCGACCTCGTAGCCCTCCAGCTTATATTTCATGA TAGCCAGCCTCTCGTCTTCATTCGGAGCTTTCAGCTCAATTTCTTGCTTGAAACAAGCCAATACCTCTGA TGGTACAGCATCCGCATCCGCTGTAGTACCTATCACAATCACTGGCCAACTTGATGAAGATTCAGAATTT GAGTTTGAAGTTTGACTTGCACCATCGATGACTTCTTCGAGTACTTTAACAATGGGGGGCGGTCTACCGA GGGGTGAATCGGATTTGGATGAGAGAGCTTCAACATGGTGGAGAACGAGAAGAGACGGGGAGCATGAAAT AGACTTTGAAAGTCGAGCAAGGAGCGTTCCTGATGTTACTGCGGGTGTATCGCCAAGTATGTCGTAACAG TCCACCTTCATCTGGATTAGGTCACAGCAGTAATTTTCATTGAAGGAGAACTTACAGTAATAATGTTGAA CCCGATGTCGTCCGCGATACCTTCTATGAGAGATCTCTTTCCAGCTCCTCGTGCGCCTTTTACGATGACT GAAAGCTGAGGCCGAAGAGCTATGGAAGTCTGGAAGAATGTAGAATTTAAAATATCCGAAAGTTTTGTGT ATGCTAACCTGGAAAATGGGGGTGGGTTCGAGCCTGCTTCCTCAATCAGCATCTTTGATTGGATACGGAG AAAGCTGCGTACGGATCCCCGACCACCTCTTATCCCATCCTTTTTTCTCAATCCGCGCCTTCTCCAGTCC CTCATATACTAATTCTGTCCCATCTCCAACCCAACATCCTAGTTCTCCAGCTCGAGCCTTGGCTGTCGTA GATGATCTAAAATCTTCTTCTATTGGAACCAGGGGATTATAAGAGATGGACGTTACAGCAAAGTAGATTA TGTTTGTTGGTGCCGGCGGTATTTTCGAGAAGCGTGGTGAGGGGCTGTCTGATTCAGAGTCAGAGTCCGT GTCACCCCCACTCTCAGCCGCAATAGACTTTTGCCGCTCCTCGTCGGTAAGAGTCTTATCCAACCAGACA GGAATACCCAGCATATCACCCCGTCTCACCATCCTCACATATCCTTGAGCATTTTCCTTCCCTTTTTGGC TTTTTGGCGCAAACAAAGTCGCCTGACCCCGAAGCCATGATCGTTCATACCGTTTATCCACCGCTTCAGC AGTTGCTATTCGTGCGAGTGTTATTTTGTTTGCGATCGGCAATGTAGGAGTCCGAGCACCAAATGGTGTA GGAACAACAGTCAGTTGAGGTAGGCTTGACGATGATGACGAGGGAATAAGAGAGCGATACAGAGACGGTG AGAGAAGGATGGTATTTGCAGGTCTGAAAATCAGATGAGCAAGGGGGACAAACAGTAAGATTAGGCTTAC AGCTCGTCATCTGGCTCGTCAAGAAGTTCCCAAGCCAAGGCCTTCGCCAGTCTTCCACTCGCTTGAGCTT GTCCTATTGGCTTCACCAACACCTACGCCACCGTTAGACAGACTCGGGATTGCAATGACAAACACTTACC CAATCACCTTCAAATATCCCTGCTCTACCTAGCCCTCCCACGCCCATCCAACAAACATCATCTCCTTCCC CATCAATGGCCTTCCCTTCGGCAACAACAGGGGTGAACCTCACCCCCCTATCTTCTGATTCTTCATGCTG CAGAACCTCTTCGACGGGGGCAGCAGGTGATATAGGTCGAACACCGGCACCAGGAGGACGGGGAGTGAGA GATCCGGAAGTAGTACTTGACAAAGTCATCAATTCTTCATCTCCCAATGCTTCGCCGTCTGGTAAATCAT CTTTCAGAGACAATGAAAGACAGGAAGAGAGGAAAACGTCAGCATCGAAGTTGGCGAGTGAAAGATGGGT CTTGCCGAAACTGCCCTCGCTCATCCCGTCTCCTAACGGCGTTTGCATTGATGGACGGGTGTCTGCGAAG AAAAACGTATTCGAGATGATAATGTTAGTTTCAGCGGTCAAAATGCCTTGATGAACGGGCTCAAGCATGA GGACCTTATACCGGTTTGTCGTTATACCCGATCGGCATGATATGATGGCCCCCTGGCGTATGATGGGATA ATTGCTATCACGCCAGATGTCCGAGAAGTTAACGTCTTCTGAAGTGTTTGAAGACGATCGATCCTCGGGG CTGTCAAACGCCGGTTGCAGGACTGCTAGAGATAGATTTACCGGCTGATGGATATGTAGGGATATCGGAA GCGGTGTCGGATAGAATGCCGGTATCAGAGATGGGTGTACTAAGATTATAGATTCCAGTCCCTGCGACAT ATGCGTTAACGACTACACATACAAATTCCGACCGAGCTGTAATCACCTTATCTTCACCTTCCTCAACCCA TACTACTGTAGACTTCCCCTTCCCTTTCCCTCGACATAATCTACCATCTTCAGGCCATTTTATAGCCACA CATATCCTATTGGTATCTCCTCCTTCTATCTCCCGCCGTCTAGTCGCGCGCAAACGATTCCATAAACTGC TGTTTACGTGAGCGGTTTGATGTGCGAAAGGACTCGAAGGAGATTGAACTACTAGCAGTGGCTCGACTTG CGCCCTCAGAGAGGGGATTTCCATGAGCATTTTTCCCTCTTTTGCTGTAAGGTCAAAGAAACTACGAATT CGGCAACGTTATGCTGACACTTTTAAGTAGACTACCACCATTACCGGACGAAAGGTTCCAAAGTTAACCG GTGTGCCTGTGGTTACGTAACTATTGTATGCCTTCTTTTTTATTTTTTGCTAGTAGGAACAGAAAAAAAA CTAAACACACACTGAGATTGGGACAAATCTACCCCTAAAAAGTCA
Protein Sequence	>gi\|799337413\|ref\|XP_012051430.1\| peroxin-6 [Cryptococcus neoformans var. grubii H99] MLMEIPSLRAQVEPLLVVQSPSSPFAHQTAHVNSSLWNRLRATRRREIEGGDTNRICVAIKWPEDGRLCR GKGKGKSTVVWVEEGEDKGLESIILVHPSLIPAFYPTPLPISLHIHQPVNLSLAVLQPAFDSPEDRSSSN TSEDVNFSDIWRDSNYPIIRQGAIISCRSGITTNRYKVLMLEPVHQGILTAETNIIISNTFFFADTRPSM QTPLGDGMSEGSFGKTHLSLANFDADVFLSSCLSLSLKDDLPDGEALGDEELMTLSSTTSGSLTPRPPGA GVRPISPAAPVEEVLQHEESEDRGVRFTPVVAEGKAIDGEGDDVCWMGVGGLGRAGIFEGDWVLVKPIGQ AQASGRLAKALAWELLDEPDDELPANTILLSPSLYRSLIPSSSSSSLPQLTVVPTPFGARTPTLPIANKI TLARIATAEAVDKRYERSWLRGQATLFAPKSQKGKENAQGYVRMVRRGDMLGIPVWLDKTLTDEERQKSI AAESGGDTDSDSESDSPSPRFSKIPPAPTNIIYFAVTSISYNPLVPIEEDFRSSTTAKARAGELGCWVGD GTELVYEGLEKARIEKKGWDKRWSGIRSNPPPFSRLAYTKLSDILNSTFFQTSIALRPQLSVIVKGARGA GKRSLIEGIADDIGFNIITVDCYDILGDTPAVTSGTLLARLSKSISCSPSLLVLHHVEALSSKSDSPLGR PPPIVKVLEEVIDGASQTSNSNSESSSSWPVIVIGTTADADAVPSEVLACFKQEIELKAPNEDERLAIMK YKLEGYEVAPDVDVRALARQTAALNAGDIDSFVHLAWNAAVKRSTSSCVSFPQAQQAGISITDEDFTHAL SKTRAAYSDSIGAPKIPNVSWDDVGGLVSVKQDILDTIQLPLERPEMFGEGLKKRSGILLYGPPGTGKTL LAKAVATSFSLNFFSVKGPELLNMYIGESEANVRRIFQRARDAAPCVIFMDELDSIAPKRGNQGDSGGVM DRIVSQLLAELDGMSSSRGGVFVMGATNRPDLLDPALLRPGRFDKMLYLSIPTTHTAQASILTALTRKFN LHPNLDIEKIAEQCPFNYTGADLYALCADAMLGAMTRQAEAVDRTIAKLNASVSMEEDPSLKTWPGELTP QYYLAKIATKEETEVVVRQQDFEEALIKLVPSVSEEELKHYERVQKEFQGYAIGKKDDVKEVKDKGKGKG KAVVVNGEAEG
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: The pex1 and pex6 deletion mutants were unable to localize the fluorescent DsRED-SKL protein to peroxisomal punctate structures, in contrast to wild-type cells. pex1 and pex6 single mutants and a pex1 pex6 double mutant exhibit identical phenotypes, including abolished growth on fatty acids but no growth difference on acetate (Idnurm et al., 2007).
References	*Idnurm et al., 2007:* Idnurm A, Giles SS, Perfect JR, Heitman J. Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans. Eukaryotic cell. 2007; 6(1); 60-72. [PubMed: 17041184 ].


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PEX6