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clpC from Listeria monocytogenes EGD-e

Victor ID 534
Gene Name clpC from Listeria monocytogenes EGD-e
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 987203
NCBI Protein GI 16802278
Locus Tag lmo0232
Protein Accession NP_463763.1
Other Database IDs UniProtKB-ID: Q8YAB6_LISMO
UniRef100: UniRef100_D2NWI9
UniRef90: UniRef90_D2NWI9
UniRef50: UniRef50_P35100
UniParc: UPI000005530C
EMBL: AL591974
EMBL-CDS: CAD00759.1
RefSeq_NT: NC_003210.1
HSSP: P03815
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0232
GenoList: LMO0232
HOGENOM: HBG413133
OMA: SRAIRRT
ProtClustDB: CLSK872619
BioCyc: LMON169963:LMO0232-MONOMER
Taxonomy ID 169963
Gene Starting Position 250591
Gene Ending Position 253053
Gene Strand (Orientation) +
Protein Name endopeptidase Clp ATP-binding chain C
DNA Sequence 
>gi|16802048:250591-253053 Listeria monocytogenes EGD-e, complete genome
AATGATGTTTGGACGATTTACGCAAAGAGCTCAGAAAGTACTCGCGTTGTCACAAGAAGAGGCGATGCGT
TTGAATCATAGTAATTTAGGAACAGAACATATTTTATTAGGGCTTGTAAGAGAAGGCGAAGGAATTGCGG
CGAAAGCTCTCTATGAACTGGGAATTAGTTCTGAAAAAGTGCAGCAAGAGGTAGAGGGATTAATTGGGCA
TGGGGAAAAAGCTGTGACGACGATCCAATATACACCTCGTGCGAAAAAAGTAATTGAACTTTCCATGGAT
GAGGCTCGTAAATTAGGCCATACTTACGTTGGGACAGAACATATCTTACTTGGGCTTATTCGTGAAGGCG
AAGGAGTTGCGGCACGCGTTTTAAGTAATCTTGGTATTAGTTTGAATAAAGCTCGGCAGCAAGTTCTACA
GCTCTTAGGCGGCGGTGATGCTACTGGGGCGGGGAGACAAACAAATACGCAAGCTACACCGACTTTAGAT
AGTTTGGCACGTGACTTAACGGTTATTGCTCGGGAAGATAATTTGGATCCGGTTATTGGTCGTTCTAAAG
AAATCCAACGTGTGATTGAAGTACTTAGTCGCCGGACGAAAAATAACCCGGTACTCATTGGGGAACCTGG
TGTCGGTAAAACAGCGATTGCTGAAGGCTTAGCGCAACAAATTGTTCGTAATGAAGTACCTGAGACCTTA
CGTGGAAAACGTGTAATGACATTGGATATGGGAACTGTTGTGGCAGGTACAAAATATCGTGGTGAATTCG
AAGACCGTTTGAAGAAAGTAATGGATGAAATTCGCCAAGCTGGTAATGTTATTCTATTTATTGATGAGTT
GCATACTTTAATTGGTGCTGGTGGGGCGGAAGGTGCGATTGATGCATCGAATATCTTGAAGCCACCTCTA
GCTCGTGGAGAGTTGCAATGTATTGGGGCAACAACGCTGGACGAGTACCGTAAATATATTGAAAAAGATG
CTGCGCTTGAGAGACGTTTCCAACCGATTAAAGTAGACGAACCAACTGTAGAAGAATCTATTCAAATTTT
ACATGGATTGCGTGATCGTTATGAAGCGCATCACCGAGTTGCAATTACGGATGAAGCACTTGAGGCCGCT
GTTCGTTTATCTGATCGCTATATTTCAGACCGTTTCTTACCTGATAAAGCGATTGATGTTATCGATGAAT
CTGGTTCTAAAGTACGTTTGAAATCTTTTACAACGCCAAAAAATGTAAAAGAAATGGAAAATAATTTATC
CGATTTGAAAAAAGAAAAAGATGCGGCTGTTCAAGGTCAAGAATTTGAAAAAGCAGCGTCATTACGTGAT
AAAGAACAAAAACTCAAAAAATCATTAGAAGAAACTAAAGCGAATTGGCAAGAAAAACAAGGGCTTGACC
ATAGTGAAGTAACAGAAGATATTGTCGCTGAAGTGGTTGCTAGTTGGACTGGGATTCCAGTTGCGAAACT
TGCGGAAACAGAGACAAATAAACTGTTAAATATGGAAAAACTTTTACATGAACGTGTGATTGGACAAGAT
GCAGCGGTTAAAGCTGTATCGCTAGCTGTACGTCGAGCTCGTGCAGGCCTTAAAGATCCGAAACGTCCGA
TTGGTTCCTTTATTTTCCTTGGACCTACTGGTGTTGGGAAAACAGAACTTGCGCGTGCACTTGCTGAGTC
GATGTTTGGCGATGAGGATTCGATGATTCGGATTGATATGTCTGAGTACATGGAGAAATTTTCAACTGCT
CGTTTAGTTGGGGCTCCTCCAGGTTATGTAGGATACGAAGAAGGTGGACAGCTGACAGAAAAAGTTCGGC
AAAAACCTTATTCAGTAGTCCTTTTAGATGAAATTGAAAAAGCACATCCGGATGTATTTAATATGTTGCT
ACAAGTACTGGATGATGGACGTTTGACTGATTCTAAAGGGCGAGTAGTTGATTTTAGAAATACAGTTATC
ATTATGACTTCCAATATTGGAGCTCAAGAAATGAAACAAGATAAATCAATGGGCTTTAATGTTACTGATC
CACTTAAAGACCATAAAGCGATGGAGCACCGCGTTTTACAAGATTTAAAACAGGCGTTCCGACCAGAATT
TATCAACCGAATTGATGAAACAATTGTATTCCATTCGCTGCAAGAAAAAGAATTGAAACAAATTGTTACT
TTACTAACTGCTCAATTAACAAAACGCTTAGCCGAACGCGATATTCACGTGAAATTAACTGAAGGTGCGA
AATCCAAAATCGCTAAAGATGGCTACGATCCAGAGTACGGAGCTCGTCCTTTAAAACGGGCTATTCAAAA
AGAAGTGGAAGACATGCTTTCTGAAGAATTGCTTCGTGGTAACATTAAAGTAGGCGATTACGTTGAAATT
GGTGTGAAAGATGGCAAGTTAGAGGTTAGAAAAAAAGATGCTCCTAAAAAGAAAACAACCTCTAAAAAAG
TAAAAGCTAAATA
Protein Sequence 
>gi|16802278|ref|NP_463763.1| endopeptidase Clp ATP-binding chain C [Listeria monocytogenes EGD-e] MMFGRFTQRAQKVLALSQEEAMRLNHSNLGTEHILLGLVREGEGIAAKALYELGISSEKVQQEVEGLIGHGEKAVTTIQYTPRAKKVIELSMDEARKLGHTYVGTEHILLGLIREGEGVAARVLSNLGISLNKARQQVLQLLGGGDATGAGRQTNTQATPTLDSLARDLTVIAREDNLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVRNEVPETLRGKRVMTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPPLARGELQCIGATTLDEYRKYIEKDAALERRFQPIKVDEPTVEESIQILHGLRDRYEAHHRVAITDEALEAAVRLSDRYISDRFLPDKAIDVIDESGSKVRLKSFTTPKNVKEMENNLSDLKKEKDAAVQGQEFEKAASLRDKEQKLKKSLEETKANWQEKQGLDHSEVTEDIVAEVVASWTGIPVAKLAETETNKLLNMEKLLHERVIGQDAAVKAVSLAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDEDSMIRIDMSEYMEKFSTARLVGAPPGYVGYEEGGQLTEKVRQKPYSVVLLDEIEKAHPDVFNMLLQVLDDGRLTDSKGRVVDFRNTVIIMTSNIGAQEMKQDKSMGFNVTDPLKDHKAMEHRVLQDLKQAFRPEFINRIDETIVFHSLQEKELKQIVTLLTAQLTKRLAERDIHVKLTEGAKSKIAKDGYDPEYGARPLKRAIQKEVEDMLSEELLRGNIKVGDYVEIGVKDGKLEVRKKDAPKKKTTSKKVKAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed a restricted capacity to grow in bone-marrow-derived macrophages, and an attenuated virulence in mice (Rouquette et al., 1996).
COG COG0542O, under O: Posttranslational modification, protein turnover, chaperones
References
Rouquette et al., 1996: Rouquette C, Ripio MT, Pellegrini E, Bolla JM, Tascon RI, Vázquez-Boland JA, Berche P. Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes. Molecular microbiology. 1996; 21(5); 977-987. [PubMed: 8885268].