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MID1

Victor ID 5333
Gene Name MID1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23887264
NCBI Protein GI 799317583
Locus Tag CNAG_03805
Genbank Accession CP003821
Protein Accession XP_012047228
Taxonomy ID 235443
Chromosome No 2
Gene Starting Position 892713
Gene Ending Position 894964
Gene Strand (Orientation) -
Protein pI 4.31
Protein Weight 40872.63
Protein Length 403
DNA Sequence 
>gi|799350600:892713-894964 Cryptococcus neoformans var. grubii H99 chromosome 2, complete sequence
TCTCTGGATGGCATGTATGCATTTCCACATATTGTGATGAATTTCACATGTAATTGTTTAGATAGCATTT
AAAATTCACCATGTGATTAACCTGAGTTTGGGACTTCTAACAGGGTGATTTATACCACATGAAATGTCTG
AATGAGGCCTTACTTTAAGTGCTCTTTGAGGGGAAATAGTTCTCTCATGCCATTGGATGGATCAAGGGTG
GATATGGATAATTATGTGAGCATCACCCCATTATTTTATTCAAAAGCAGTGCAGCCATTGCAAGTACTGT
TCCCTTTACTGGTTGGTGTTCTGTATGCTGTCATGTCCTATTTTGCATGATGCGATTAGACAAGGTAGCT
CAAGGCAATCACTAGGTACAAGGACATCACTACAAAGTAGTAAGCTCCTGCAATTCCCAGTGAAATAGAA
TAAAACAAGACTTACACATAACACCCTCCATGTAATTGCTGCGACCTGTAACCAGAAATGATGCATTAAG
TATCCACTTGCCAGATTAATGTAATAATTAATAATTAGACCCACCATCTTGCAGCAGTAAGTTGACCAGC
ATCACTGACACAAACAGGACAATTGTCTCAAAGTTGGCCTGATGGAAATCAGCTTGAAGCCCAGTGAGTT
CTCAGACTGTGACTCACAAAGAAAAGCGTTAGATCCTTTTGAAGGGGCCATGCAATGATGACCAGTAGTG
GGATCATGCCTGCAGCAATTTGAATGCTAGACCCAACACTTACACCAATGGTAAGCTCCATCTTGCCTTT
GCAAGCCATCCAGACAGATGTGACATGCTCAGCAGCATTGCCCACAAGAGGAAGAAGGATGAGCCCAATA
AACCTAATAGCATCAGCAACAGCTTTTTTGGACCCCAAAGGCTTACCTTTTGGGGATATTCCATTGCTGA
GCTGTCTCGTCAATGCTGCCAACAAGAATATCTGCACAGAACGCAGTGATAACTGTTATGATTAAGAGCC
AGATGCCAGCACTCCATTGATCCATTTCCGCAACCTCCATTTCTTCTGCCTCTTCATTCTCAGCTTCGAA
TAGACCTGAATGAGTCCGCAGCTGAAAGTAAAGATACCCAAAATAAGTTAGGAGGAGAATGACAGAAGTG
CCTCGCGAAAGGAGGAGGAGACCTTTGAGGAATTCATCGGGAGAATCGGAGACTTCTTTACCCAACAAGG
TGCCAACAAGAGAGTTACTTTTGTCAATCTCTGAGGCGTGATCTACTGGGTGATCAGTCCAATCCATATA
CACCACCGTGAATTGAAATGAACCTACAGGCGGCTGGTAGGATCAATGTTATACAAGCAAGCGTCATCAA
TGATGAACTTGCTTGAGCAGCTGTGGCCTGAAAAGTGGATTCGTAGAAGAAGAAACCAGCCCTTGAACAT
ATCAGCTTCATTGCCGCGGAGCTGAATAGCTTGTGAAACTTACGCAAAGAAGCTCATGCCCAAAACCAAA
AGTAAATTTGAAAGCACACTGCCCAAAAGGGACCTTTGAACAAGCTCTAATTCATCTAGATATAGGTGGG
ACTAATCAGCATTGATATACACTTAATTATTGACTAGACTTGCTCTGTCGTAAAGCGACAATGGCAACAA
TCAACTCGACTGCATTACCGAAGCTTCGAAGAACATATTATATTAGCTTTGAAAGATGATGACTTTGAGA
TGATTTACGTCGCATTCAGAAGACCTCCAAGTGTTTGCCCGAGTTTCATGGACAGCTGCTCTGTACTGTC
CCCTAGAAGCTAATACAAGCGAGTGGTTAGTTCTTAGACAGGGATTGTAGAGTAGACATTTGCTCGACGC
ACCTTGGCTAGCGGAACAATCGCCAGGAAGGATGTCGTGAAGCGCGCGGCGGCACTCCAACCGAGCGCCT
CGGCTACTCACAAACCACGAAATCAATAAAACTTGTGAATGCAAGCGATCGTCGGCTGTCCACTGACCTA
TGAGACTAAGAGGGACACAAATCAGGAGAACGTTAATCCAGGATCCCAGCATTAGGTATCTAGTGGAACC
CAACAAGTCGAAGGGTTTCGAGGCGGAAGGGTGATCAGACGCCTGGGAAGGAAGGAGTGGAGATGTCTCG
AGTGAGGCCATAATGAGTATGTATAACAGCCCAGTTGAGATACTGCTGTGAGTGCAAGAGGTAACAGAAG
GACTATGAATTTCGATCAAATGCGTGTTAGGCTACGAGCGTTGCGGGATCTGATGATGGATATCAAGGCT
GTACCTGTACCG
Protein Sequence 
>gi|799317583|ref|XP_012047228.1| calcium/proton exchanger [Cryptococcus neoformans var. grubii H99]
MASLETSPLLPSQASDHPSASKPFDLLGSTRYLMLGSWINVLLICVPLSLIAEALGWSAAARFTTSFLAI
VPLAKLLGDSTEQLSMKLGQTLGGLLNATFGNAVELIVAIVALRQNELELVQRSLLGSVLSNLLLVLGMS
FFAAGFFFYESTFQATAAQASSSLMTLACITLILPAAYHASEIDKSNSLVGTLLGKEVSDSPDEFLKGLL
LLSRGTSVILLLTYFGYLYFQLRTHSGLFEAENEEAEEMEVAEMDQWSAGIWLLIITVITAFCADILVGS
IDETAQQWNIPKRFIGLILLPLVGNAAEHVTSVWMACKGKMELTIGVSVGSSIQIAAGMIPLLVIIAWPL
QKDLTLFFANFETIVLFVSVMLVNLLLQDGRSNYMEGVMLMSLYLVIALSYLV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Mid1, a binding partner of Cch1,function as a store-operated Ca(2+)-selective channel gated by depletion of endoplasmic reticulum (ER) Ca(2+) stores (Hong et al., 2013).
References
Hong et al., 2013: Hong MP, Vu K, Bautos JM, Tham R, Jamklang M, Uhrig JP, Gelli A. Activity of the calcium channel pore Cch1 is dependent on a modulatory region of the subunit Mid1 in Cryptococcus neoformans. Eukaryotic cell. 2013; 12(1); 142-150. [PubMed: 23175710 ].