Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

MET2

Victor ID 5330
Gene Name MET2
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23884846
NCBI Protein GI 799326475
Locus Tag CNAG_01103
Genbank Accession CP003824
Protein Accession XP_012049059
Taxonomy ID 235443
Chromosome No 5
Gene Starting Position 1203224
Gene Ending Position 1204452
Gene Strand (Orientation) +
Protein pI 9.78
Protein Weight 23630.42
Protein Length 218
DNA Sequence 
>gi|799350697:1203224-1204452 Cryptococcus neoformans var. grubii H99 chromosome 5, complete sequence
TCTTCGTTCGTTTCCAACCCACCATATCCCAGGAGCGAATATAAGCAGCGTAGGAGGATAACTATGGGTA
AGTACAGCTCTATAAACTGTATATTGCTCAATGATAGTGCTGACGTCTTCTCTGAATGCAGATTACCAAG
TGAGCAGTAGCTGTCTGTTTTCCTTATCAACAAAATGTACTAACCCATTTGCAGAATCGAGCAGGTGCGA
ACAAGGGTAGTGGTGGTGTCGGTGAGTGTTATACATTCATCAAAATACGGCGCACTATTGACATATTTCT
GTGTAGCTGGTGCATCCGAAACAGCAGTGGACAGGAGAGAACGCCTTCGAAAACTTGCTTTGGAGACTAT
TGACTTGGCCAAAGATCCCTATATCCTCAGGTCAGTGCTTGTGCTTGTTACGATGTCAAATTATTGATTT
CTGACATTTTTTCATTCATAGAACCCATCTTGGTACATTAGAATGCCGTCTTTGTCTCACTCTACACGTT
AACGAAGGTTCTTACCTTGCCCACACTCAAGGAAAGAAACATCAAACAAACCTTGCCAGGCGTGCAGCCA
AGGACAACAAGGATCAGGCATTAATGATACAAGCTCCCACTGCCGCGCAACAAGTGAAGAAGAAAGTGTT
TGTCAAGATTGGAAGACCTGGTAAGTCGGTTCCGATGTCGATCTTGCCCCTTGGGAATCTGACCGGCGCC
GCTAGGTTACAAAATCATCAAGATTAGAGAGCCTGTCAGTCAAAGGATGGGTCTGTTATTCACTGTCTCG
TTACCTGAGATAAAAGCGGGAGAAAGGCCAAGAAGGAGGTTCATGTCTGCTTTTGAGCAACGGCGAGAGA
TTCCCAATAAAGCCTTCCAGTACTTGGTTGTGAGTTGAACTCAGTCGGACATTTCCTTCACCCTGCTAAA
CAATAGATTGTAGTTGGCAGCCGAGCCATACGAGACCATAGCATTTGCCATCCCCTCAAAAGAGATGGTT
GACGTTGATGAAGACCCAGAGTCGACATGGGAGCACTGGGATGCCGACGAAAAGGTTTACAGTTGTCAAT
TCTTGTACAAATAAATACTATAAGGTATGATTGACATATTGTATGATTACTATGCAGCATCTGCTTGATT
TGACTGGAGGATGTGATTAATGCGGTACGCAGCTTTCATGACGGAAACCATCAAGGCATCCAAAAAGGTC
ATGCAGGGACGAATACTTAATGCAGTAATGCATGGCGCT
Protein Sequence 
>gi|799326475|ref|XP_012049059.1| splicing factor 3A subunit 2 [Cryptococcus neoformans var. grubii H99]
MDYQNRAGANKGSGGVAGASETAVDRRERLRKLALETIDLAKDPYILRTHLGTLECRLCLTLHVNEGSYL
AHTQGKKHQTNLARRAAKDNKDQALMIQAPTAAQQVKKKVFVKIGRPGYKIIKIREPVSQRMGLLFTVSL
PEIKAGERPRRRFMSAFEQRREIPNKAFQYLVLAAEPYETIAFAIPSKEMVDVDEDPESTWEHWDADEKV
YSCQFLYK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: met mutants showed attenuated virulence in a mouse model (Nazi et al., 2007).
References
Nazi et al., 2007: Nazi I, Scott A, Sham A, Rossi L, Williamson PR, Kronstad JW, Wright GD. Role of homoserine transacetylase as a new target for antifungal agents. Antimicrobial agents and chemotherapy. 2007; 51(5); 1731-1736. [PubMed: 17353245].