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MAC1

Victor ID 5329
Gene Name MAC1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23889624
NCBI Protein GI 799346943
Locus Tag CNAG_06415
Genbank Accession CP003832
Protein Accession XP_012053482
Taxonomy ID 235443
Chromosome No 13
Gene Starting Position 421280
Gene Ending Position 425162
Gene Strand (Orientation) +
Protein pI 5.09
Protein Weight 101183.83
Protein Length 1054
DNA Sequence 
>gi|799350950:421280-425162 Cryptococcus neoformans var. grubii H99 chromosome 13, complete sequence
GTAAGAGTTAAGCTTTGTAATGGTGATTAGAAATGACTAGAGGGTAATTAGAATCTAGTTGGAAAGACGA
TTACAAATCATCGGCCGACGTCACCGCCTTCGGAAGTTGATTAATAATTTGTTTTCACAGGCGGCTCTTA
CTTCCGCAAACCGAATATCATTTCAGTTCTACTTTGTCCCTCATCATCTGCACCTCCTTATTCTCTACTT
ATATACCAGAGCGCCTAGAACAGAAATACGTCCACCGCAATTTACAGCTCTCGAGCAGACACATCCATCG
ATATTCAACATGGCCACATTTGCCAGTCCTCCACGTAGGCAACGCTCTGCTTCAAATAGCAGCCTCTTGT
CCTCCATCGTGAACACAATCCCTGCGCCCCTTACCAATTTATTCACTTCTCCAAGAGTAGAACAAAGGGT
TTTGCTCGAAGAAGACGAAGTTCCGCTAGAAGAAGGGAGTCAATCGCTTAGTAAAGAAGCTCCTGTAGGA
TTACGGAGAGTCGAACTGAGAATAGGAGGAATGACCGTGAGTGGGGGTTTCACATGTTTTGAGTCCGCGT
CAAGCTAACATGAGAGATAGTGTGGAGCCTGTGTGGCGTCCATTGAGTCTCAGTTGAAGCAGCCCGGTAT
TGAAAGCATCCAAATATCTTTGCTTGCTGAGCGAGGAGTGGTAGAGTACGACGAGACCTTTGTCAAGGCG
GATGGAGAGCATTGGACAGGCGATAAGATCGCCGAGGAAATAGAAGACATTGGATTCGAAGCCACTGTTG
TTGAAAAGAGTGAAGTACAAGAGGTAGAATTGCGTGTATACGGGTAAGTCGCTGTGACCAGCATAGAGTC
ACTGCTAATCTGTCGACAGACTGGAGAACCAAGAAATAGTTGGCAGTTTGATATCGACCACAGAGGGGAT
CCCTGGTGTCCATTCTGCCGTTCTTCTGCCGCCTTATTCCCACCTCGCCCTAACACATTCCCCTCTATTA
ATCTCTCTCCGTTCAATCGTCGACACCCTTTCAGCATCTTTCCCACAGTTATCGTTCTTACCAGTATCAA
ACAACGATGATTCTCAAATAGCGTCTCTGCAAAAGCACAAGGAAGCAGCTCTATGGAAAAGAACGCTTAT
TCTATCAGCCATATTTGCTGTCCCTGTGTTTATCATTGGGATGCTAAGCATGTATCTGCCGAGGTGGTTG
ATGGGATGGACTATGTGGAAAGTAGCCAGGGGGATCTATCTTGGAGATCTCGTCTGCCTGGTGCTTACAC
TGCCTGTGCAAACTTGGCTGGCAAAGAAGTTTTATCAGAACGCTTGGAAATCTATCAAGCACGGATCAGC
TACCATGTACGTGATTCTCCATCTATGTTTGTATTTGCTGCTAATCCAAAATAGGGATGTTCTGGTTGTT
CTTGGAACATCCTCTGCTTTTTGTTACTCTGTCCTTGCCATGTTCTTCGCCATGTTCTCATCCGACCCGG
ATTACCACCCTCAAACATTCTTCGACACTTCCACCATGCTAATCACTTTTGTGTCCCTTGGTCGGTACAT
CGAAAACATCGCCAAAGGCAAGACTTCCGCTGCACTTACCGACCTCTTGTCCCTCACTCCTTCCTCCGCT
ACGATCTACGTTGATCCCCCTGCGGAGGGCGAGCTGCCGGATTCTTCTGCCAAGACACGTAAGGTACCTA
CTGAACTCGTTCAAGTCGGTGATGTCGTACTTCTTGTTCCTGGTGAGAAGATCCCGGCCGATGGTACCGT
CTTAACCGGCTCAACATCAGTTGACGAATCCATGGTAACTGGCGAAGCTCTTCCCATGCCTAAAACAGCC
GGTTCTCAGGTGATCGGTGGTACGGTAAACGGATTGGGTACTATCACCTTCCGGGTCAGCCGCGCTGGGG
CCGACACCGCCCTTTCCCAGATTGTTAAACTCGTAGAGGATGCTCAGACTTCAAAGGCACCTATCCAACA
GTTTGCCGATCGCGTCGCTGGTATCTTTGTCCCCATTGTCATCACCCTCAGTTTGTCGACCTTTGTGATA
TGGATGATCATTTCGCTTCTCTCGTCTTATGGCAGCTTGCCAGATGTTTTCCATTCTCCCGGTGTGGGCA
GATTTGGTGTTTGTCTCAAGCTCTGTATCTCTGTGGTCGTCGTGGCTTGCCCGTGCGCTTTGGGTTTGAG
CACCCCTACGGCCGTGATGGTCGGTACAGGTGTCGGCGCCAAGAACGGTATCCTTATCAAGGGCGGAAAA
GCCCTGGAAGCGTGCAAGGGCGTCAAAAGGGTTGTTTTGGACAAGACTGGAACGGTGACAGAAGGCAAGA
TGGCTGTTGCCTCGGTCGTTTGGGCTTCCTCGTCTAGTGCTGCCAACATTGGACAAGGGGATTTGGACAC
TGCTGCTACGTTGTCTATTACCACATCTGCCAACCCTCTTCAACGACACACTATCATCTCCCTCATTTCT
CTTGCCGAAGCCAGGTCTGAACATCCCTTGGGTATGGCTGTTGCAGCGCATGGACGTGAAATTCTCTCCA
ACGCTGGCCTTCCACCTCCCAACGGCGAGGTCGTTGAGTTTGAGAGCCATACCGGTGAAGGTCTCGAGGC
CGTCGTCAAGCTTTCTGGTGGTGCGGTTGAGGAATGTATAAGAATTGGCAAAGCAGATTTTGTATTGTCC
AACAGCAAAGCTGACGAAGCTTATGCTGAGAAGCAACTCAGTATGCCAAGCGAAATCCTCGAGTTTGAAC
ATGACCAAATGGCTCTTGCCAGGACCGTCATCTTCGTCTCAATCATCCGCCCTACGGGTGTGGTTCCCGT
CGCCGCCTTCTCTTTATCCGACTCCCCCAAAGCAACTTCCGCTCAAGCCATCCGTGCCCTCAAGGATATG
GGCATCAAGGTAACCATGCTTACAGGTGATGCCGCTGCTACAGCTCAAGCGGTTGCTCGACAAGTGGGTA
TCGACGAAGACGAGGTTTACTCTGGCGTCAGCCCCAAAGGAAAGGCCAAGATTGTCCAGGATCTTGATGA
AGCCAGTGGTGGCGTGGCCATGGTTGGCGACGGTATCAATGATTCTCCCGCTCTTGTTGCTGCTTCTCTC
GGTATCGCTCTTTCTTCTGGTACATCTATTGCTATCGAAGCGGCCGATGTCGTCCTCGTGCGATCCGACT
TGCTGGACGTTGTTGCAGCACTCGACTTGGGTCAAGTTATCTTCAGGAAAATCAAGGCCAACTTGATCTG
GGCGTGCTGCTATAATGTGCTGATGATCCCCTTGGCGATGGGTGTATTGTTGCCGTGGGGTATCCATCTT
CATCCAATGATGGCTGCGGCCGCTATGGCGTTTAGCAGTGTTTCCGTTGTGGTGTCGAGTTTGACTTTGA
AGGTGAGTATATCGAATTGTTACACTCTTATGGCGCTGACCGCGTTTTTTTTCCCCTCCTTTTTTCTTTT
TGGCAGTGGTGGACTCGGCCCCAGTCGTCAATCGCTTCTAGAGAAACCTATATTCCCCCCAGTCCTCGCA
AGAGTGTTGTGTCTGTCTTCGCCGAAGGCGCCAGAGACACCATCATGGATGGTGTTGATCGCGTTGCAGA
GAAACTACCTTTCTTGAAGAGATTTACTGAAAGAAGGGGAAATGTATCGTCGACGGCCGAGTACGAGGCT
ATTCCTCTAGGTCAAGCGGGATCGTATGAGGTGTAGGTTATGTTCGTCTCTTATATTACTTTTGGGTTTA
TTTCTTGTTCATTTTCGTAGTCATCTGTGTACACCTTTTGAATATTGAATTATGTATCCTATGTCATTGT
TTTCTAGTTTTATTTTTAATTTCCAAACTGATAGTTGTACAACATGCTGCATTTGTGTTCCTTCTACATC
TAAATGTAGTTTTTAATCTAATGGTGTACAGTC
Protein Sequence 
>gi|799346943|ref|XP_012053482.1| Cu2 -exporting ATPase [Cryptococcus neoformans var. grubii H99]
MATFASPPRRQRSASNSSLLSSIVNTIPAPLTNLFTSPRVEQRVLLEEDEVPLEEGSQSLSKEAPVGLRR
VELRIGGMTCGACVASIESQLKQPGIESIQISLLAERGVVEYDETFVKADGEHWTGDKIAEEIEDIGFEA
TVVEKSEVQEVELRVYGLENQEIVGSLISTTEGIPGVHSAVLLPPYSHLALTHSPLLISLRSIVDTLSAS
FPQLSFLPVSNNDDSQIASLQKHKEAALWKRTLILSAIFAVPVFIIGMLSMYLPRWLMGWTMWKVARGIY
LGDLVCLVLTLPVQTWLAKKFYQNAWKSIKHGSATMDVLVVLGTSSAFCYSVLAMFFAMFSSDPDYHPQT
FFDTSTMLITFVSLGRYIENIAKGKTSAALTDLLSLTPSSATIYVDPPAEGELPDSSAKTRKVPTELVQV
GDVVLLVPGEKIPADGTVLTGSTSVDESMVTGEALPMPKTAGSQVIGGTVNGLGTITFRVSRAGADTALS
QIVKLVEDAQTSKAPIQQFADRVAGIFVPIVITLSLSTFVIWMIISLLSSYGSLPDVFHSPGVGRFGVCL
KLCISVVVVACPCALGLSTPTAVMVGTGVGAKNGILIKGGKALEACKGVKRVVLDKTGTVTEGKMAVASV
VWASSSSAANIGQGDLDTAATLSITTSANPLQRHTIISLISLAEARSEHPLGMAVAAHGREILSNAGLPP
PNGEVVEFESHTGEGLEAVVKLSGGAVEECIRIGKADFVLSNSKADEAYAEKQLSMPSEILEFEHDQMAL
ARTVIFVSIIRPTGVVPVAAFSLSDSPKATSAQAIRALKDMGIKVTMLTGDAAATAQAVARQVGIDEDEV
YSGVSPKGKAKIVQDLDEASGGVAMVGDGINDSPALVAASLGIALSSGTSIAIEAADVVLVRSDLLDVVA
ALDLGQVIFRKIKANLIWACCYNVLMIPLAMGVLLPWGIHLHPMMAAAAMAFSSVSVVVSSLTLKWWTRP
QSSIASRETYIPPSPRKSVVSVFAEGARDTIMDGVDRVAEKLPFLKRFTERRGNVSSTAEYEAIPLGQAG
SYEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mac1D mutants exhibit defects in filamentation, melanin production, and high
References