Victors

ilv2
Victor ID	5321
Gene Name	ilv2
Sequence Strain (Species/Organism)	Cryptococcus neoformans var. grubii H99
NCBI Gene ID	23884226
NCBI Protein GI	799314770
Locus Tag	CNAG_00418
Genbank Accession	CP003820
Protein Accession	XP_012046704
Taxonomy ID	235443
Chromosome No	1
Gene Starting Position	1096620
Gene Ending Position	1098763
Gene Strand (Orientation)	-
Protein pI	5.67
Protein Weight	40560.04
Protein Length	397
DNA Sequence	>gi\|799350543:1096620-1098763 Cryptococcus neoformans var. grubii H99 chromosome 1, complete sequence TGGTTTGTGGCGGTTGAGCGCATTGCATAAAGTACCGGAAACCGACAGCCCTACACATGATCTAATGTCT TTTTATCTATAATCTCACCAAATCAACAGAACTAGAACCAGTAGTAGAGAAGCGGGTAGGGATATACAAC CTCGCCTCGCCTTCCAGAAAACCCAAAAGACAAGGTCGAAAAGAAATGAGCGAAAGATACGAAAAAAGGG TATATGCGTTGTGATATAATAAATGCGTTTTACTGTTGGAGAGATTGTCATGGGAAATCGTGCTGCTTGT AAGACAAGAATGCGAATGATATTGAACGGAGCGAGGAGGAACTCGCATGGGTCCTTAGTAGGTATCCCAT ATTAAAGATTAAGAGGAAGGAAGAGAGACCCAAGCATGAGAGACTAGCAGCTTAGAAGTTGAGCTGCTTG GGCTGCTCCCAAGAGTAGGCAGGGTTACCGAAGTGACCGTAAGCGGCAGTCTTAAGGTACTGGGGCTGCT GGAGGTTGAGAGCTTGGACTGTGGGTGACATTAGCAACTACCGCAAGATGTTTCTTTCTCGAAAAAACGT ACCGATAAGTCCGGGTCGGAGGTCGAAGTTCTGCCTGATAACGTCGACAAGCTCGGCGTCGCTCTTCTTG CCGGTACCGTAAGTGTCGACGAAGATGGAAAGGGGTTCAGCGACACCAATGGCGTAAGAGAGCTGGACCA ATGCTCGTCGGGCGAGACCAGCAGCGACGAGGGACTTGGCGATCCATCGAGCAGTGTAGGCGGCAGATCG GTCAACCTTGGACCAGTCCTTACCGGAGAAGGCACCACCACCGTGAGCACCCCAACCACCGTAGGTGTCG ACAATGATCTTTCGGCCAGTGAGACCGGCATCACCCTGAGGACCGCCAATGACAAATCGGCCGGAAGGCT GGATGTGGTAGATAACTCGGTCGTCAAGAAGGTTCTTGGGGATAACCTTCTTGATGATCTTCTCAAGGAT CTCCTCTCGGAGCTGCTCGGTAGAGATCTCCTCAGCGTGCTGAGTAGAGATGACGACAGTGTCGACACGG AGGGGGATCATAGCACCATCCTCACCCTTCTTGTACTCAACGGTGACCTGGGTCTTAGAGTCGGGTCGGA GCCAGCCCATAGAGCCGTCACGACGGGCAGTGGCCATAGCGGCGTTAAGCTTGTGGGCGAGCATGATGGT AAGAGGCATCATCTCGGGGGTCTCGTCGGTAGCGTAACCGAACCTGATAAAGTCGTCAGCTCTCGCCTGC ATGACGGACTCATGCGATAAACCCACATGATACCCTGATCACCAGCACCAATCTTCTCGAGGGCACCGTG GTCGAGACCTTGAGCAATGTCGGGAGATTGCTGCTCAATGGCAACCAAGACGTTACAGGTCTTGTAGTCG AAACCCTTCTCGGAAGAGTCGTAACCGATCTTCTTGATGGTGTCTCGGATGACCTTCTGGTAGTCGATCT GCGCCCTGGTGGTGATCTCACCGAAGACCATGATCATACCGGTCTTGGCGGCGGTCTCACAGGCGACCTA CGGAACACAATGTCAGTCGAGGGACCAAAGATGAAACATGGTGTATGGATGCATACCTTGGAGAAAGGGT CCTCAGCGAGACAAGCGTCGAGGATGGCATCAGAGACCTGATCACAGATCTTGTCGGGGTGGCCCTCACC AACGGACTCGGAAGTGAAAAGGAAGCTGTATCGAGGCAAGGGCAGCAGTGGCAATTATACAGGGCAAAAC AGGGGGCGGTGGGAAGGATAGGCAAAGATGGGCAAAAACCAAAAACCAGCCGTCAGCAGCCAATTCTCTC CAATAAGCCCGTCGAGTCGCAGAAAACGTGCGATGCTGTTCTACCGCGAAGAGAAAAAACACTCACTGCC CGGGAGCCAAGTCAGTAGCGGGACCATTACCGTTAACGTTGACAGCAGTCATTTTGTATATAAGTAGGTG GGTGGGGGGGGTGGGGGTGTTTCAGACAAGAAAGGTAATTGGAAAAGAGATAAAAGAGAGGATGAAGATT TATACGGTGACGAGGAAAACAAGGGCAAAAAAAATGGAACCATAGTTGCCCTGTCCCTGCGCCGACGCCC GACCCGCCGACCAGACGATGGCGTGCGAGCCAGGAACAGGAAAA
Protein Sequence	>gi\|799314770\|ref\|XP_012046704.1\| S-adenosylmethionine synthase [Cryptococcus neoformans var. grubii H99] MTAVNVNGNGPATDLAPGHFLFTSESVGEGHPDKICDQVSDAILDACLAEDPFSKVACETAAKTGMIMVF GEITTRAQIDYQKVIRDTIKKIGYDSSEKGFDYKTCNVLVAIEQQSPDIAQGLDHGALEKIGAGDQGIMF GYATDETPEMMPLTIMLAHKLNAAMATARRDGSMGWLRPDSKTQVTVEYKKGEDGAMIPLRVDTVVISTQ HAEEISTEQLREEILEKIIKKVIPKNLLDDRVIYHIQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHG GGAFSGKDWSKVDRSAAYTARWIAKSLVAAGLARRALVQLSYAIGVAEPLSIFVDTYGTGKKSDAELVDV IRQNFDLRPGLIVQALNLQQPQYLKTAAYGHFGNPAYSWEQPKQLNF
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: The Cryptococcus neoformans ILV2 gene, encoding acetolactate synthase. The ilv2 mutants were auxotrophic for isoleucine and valine and the auxotrophy was satisfied by these amino acids only when proline, and not ammonium, was the nitrogen source, indicating nitrogen regulation of amino acid transport (Kingsbury et al., 2004).
References	*Kingsbury et al., 2004:* Kingsbury JM, Yang Z, Ganous TM, Cox GM, McCusker JH. Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37 degrees C and in vivo. Microbiology (Reading, England). 2004; 150(Pt 5); 1547-1558. [PubMed: 15133116].


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ilv2