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plcB from Listeria monocytogenes EGD-e

Victor ID 532
Gene Name plcB from Listeria monocytogenes EGD-e
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 987036
NCBI Protein GI 16802251
Locus Tag lmo0205
Protein Accession NP_463736.1
Other Database IDs UniProtKB-ID: PHLC_LISMO
UniRef100: UniRef100_P33378
UniRef90: UniRef90_P33378
UniRef50: UniRef50_P33378
UniParc: UPI0000054E0D
EMBL: M82881
EMBL: X59723
EMBL: AL591974
EMBL-CDS: AAA25270.1
EMBL-CDS: CAA42408.1
EMBL-CDS: CAD00732.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0205
GenoList: LMO0205
HOGENOM: HBG340118
OMA: RANLMNE
ProtClustDB: CLSK895085
BioCyc: LMON169963:LMO0205-MONOMER
Taxonomy ID 169963
Gene Starting Position 211424
Gene Ending Position 212293
Gene Strand (Orientation) +
Protein Name phospholipase C
DNA Sequence 
>gi|16802048:211424-212293 Listeria monocytogenes EGD-e, complete genome
TATGAAATTCAAAAAGGTGGTTCTAGGTATGTGCTTGATCGCAAGTGTTCTAGTCTTTCCGGTAACGATA
AAAGCAAATGCCTGTTGTGATGAATACTTACAAACACCCGCAGCTCCGCATGATATTGACAGCAAATTAC
CACATAAACTTAGTTGGTCCGCGGATAACCCGACAAATACTGACGTAAATACGCACTATTGGCTTTTTAA
ACAAGCGGAAAAAATACTAGCTAAAGATGTAAATCATATGCGAGCTAATTTAATGAATGAACTTAAAAAA
TTCGATAAACAAATAGCTCAAGGAATATATGATGCGGATCATAAAAATCCATATTATGATACTAGTACAT
TTTTATCTCATTTTTATAATCCTGATAGAGATAATACTTATTTGCCGGGTTTTGCTAATGCGAAAATAAC
AGGAGCAAAGTATTTCAATCAATCGGTGACTGATTACCGAGAAGGGAAATTTGACACAGCGTTTTATAAA
TTAGGCCTAGCAATCCATTATTATACGGATATTAGTCAACCTATGCACGCCAATAATTTTACCGCAATAT
CATACCCTCCAGGCTACCACTGTGCATATGAAAATTACGTAGATACCATTAAACACAATTATCAAGCAAC
GGAAGACATGGTAGCAAAAAGATTTTGCTCAGATGACGTGAAAGACTGGCTCTATGAAAATGCGAAAAGG
GCGAAAGCGGACTACCCGAAAATAGTCAATGCGAAAACTAAAAAATCATATTTAGTAGGAAATTCTGAAT
GGAAAAAGGATACAGTGGAACCTACTGGAGCTAGACTAAGAGATTCACAGCAAACTTTGGCAGGTTTTTT
AGAATTTTGGTCTAAAAAAACAAATGAATA
Protein Sequence 
>gi|16802251|ref|NP_463736.1| phospholipase C [Listeria monocytogenes EGD-e] MKFKKVVLGMCLIASVLVFPVTIKANACCDEYLQTPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVAKRFCSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutants showed reduced virulence in mice, escape from vacuole and cell-to-cell spread (Smith et al., 1995).
References
Smith et al., 1995: Smith GA, Marquis H, Jones S, Johnston NC, Portnoy DA, Goldfine H. The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread. Infection and immunity. 1995; 63(11); 4231-4237. [PubMed: 7591052].