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HXT1

Victor ID 5319
Gene Name HXT1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23886943
NCBI Protein GI 799336417
Locus Tag CNAG_03438
Genbank Accession CP003827
Protein Accession XP_012051260
Taxonomy ID 235443
Chromosome No 8
Gene Starting Position 949210
Gene Ending Position 951944
Gene Strand (Orientation) -
Protein pI 7.73
Protein Weight 52520.11
Protein Length 520
DNA Sequence 
>gi|799350780:949210-951944 Cryptococcus neoformans var. grubii H99 chromosome 8, complete sequence
AGACGCATGCAACATCATGTCCATGTAATGTATGTGCATGTATGGAGCTATTTGCTCGTAATCCATGTGT
ACGGATAATAAACGAAAATAAATCGCGGGAATTGATCTAAACCGGATTCTTGATAAATTAATATGTAAAT
CTAACAAAAATAAGACAAAGCCAATTTCTTCCAATTTGCGAAAAAAATTACTCTGGGTTGGTACATGACC
AAGGCCCGTTCTTTGTTATCCTTGCAATCAACATTGTACAACACACTTCTTGTTCGTCTCTATCTCTCTA
ATGTTCTAGGCCAGATTAATAAAATAAAATTGAGAAGGGGGTGGGAACGAGAGAGCTTTATTAGACAATC
CTGTCGTCCTCAGCGCTGGTTCGAGCGCTAGTCTGTTGGCTAGATTTGACCTGCTCGTTCTCAGCGTGGA
TAGATCGAGAGTAGTGCTTCTCTTGCGCATTTTGAGCCCTAGCCAGCTGCTCATCCACAAATTTGTGAGA
TCGCCAAGCGGGAGTGTGAGAGAGATAGAGCGCATCTACCTGTTCGATGGACATCGATCTCGTCTCAGGA
ATGCAGAAGAAGGCAAAAGAAACAGAAATCGCGAGACAGCCGGCCCAAACAAAAGTGATACCAGTACCAA
TTCGGGCCTGGATCTGAGGAGCAGCAAAGGCGATGATGAGGTTGAAGAGCCAGTTGGCACCGGTACCGAG
AGTGACACACAGAGAAGACAACCTGATGGGGAAAGTCTCACCGCAAACAACCCAGGCGATAGGACCCCAA
GATGACGCAAAGGACGCAATGAAAAGACAGGTAAAGGCAATGAGGACATCACCGGCAATCTTGTCATCAG
GGTAGGCCTTGGAGACAGCACCGACAACGATTTGACCAATAAACATGAGAATGCCACCGATAAGAAGGAT
AGGTCGTCGACCAGCTCGGTCGACAGCGAGAATACCGGGGAAAGAGAAGAGGACGTTGACGGAAGCGAGA
ATGATCTGGAAGACATAGGTATCGTCAAGACCGGCAGTCTGGGCGAACTGGACACCGTAAGAGAAGAAAA
AGTTGACACCGGTGATTTGCTGCCCGATCTGGACACAGATACCAATCATAGTTCGCCAGAGAATTCGGTC
CTTAGTGGAGAAGCATTCAACATAGCTGGCCTGACCGCGCTCCTGGTCCTTGATGGTAGCCTCACGGACT
TCCTCCATCTCGGTCTATACCCGTACGGTCAGCAAATGTTTTTTGACGCACAATGACATAAACGACTCAC
ATCGATGTCAGGGTGATCGACAGGAAGACCACGGAGATTGGCAAGGTTCTTTCGGCAATGTTCCCATCTG
CCCTTCTTGGCAAGGAATCGGGGAGACTCGGGGGAAAAGAGGAAACCAACTAGCAACAAAGCAGCCCAGA
CCATTTGAAGAGATACGGGGATTCGCCATCTATAAAAGGTACGCCATCAGCCTCAATTTCAGCTGAATTT
TCTAGAAAAGAAAAAAAAAGACTAACGAGACATCACCGGCATAAGAGCTCATACCCCAGTTGGTCATGGC
AACACCCCAGATACCAAGAGTAACACAAAGCTGGAAAGAACCAGTGACGAGACCTCGGTATCGAGGAGGA
GAAGCCTCAGCCTGGAAAACGGGAACAAGACCAGAGGTAGCACCGACACCGAGACCGGTGAGAAGACGAG
CAACGCAGAGTTGACCATAGGTGTTAAAGGCAGAAGTCTGGAATGATGCCGATCATTGTCAGTTGATTGA
TCGACAGTGTCCCAAAGGATGGTAAGAAAGGTGTTTACGTACCTCGATGGCAGCACCACAAAGGTAGATG
AAGATGAAAACCATACAGGTCAATCGCAAACCGAACTGTGAAAATTAAGATATTAGCACATGACATCACC
GGCTATTTTCAAGTTCTGTCCTCGAACATAGCAACAACTGCGAAGACTTCGATTTGTGCAATGTAACACC
AAAAGAACCACTCGACAAATGTTGTGGAGCTGAAGATAAACGAGCCATGGAAATCAACTCACTCGGTCAG
CAATAGAACCGGAACCAACAGCACCAATGACAGCGCCGACTGACAAAAGACCGGTAATGGCAGATTGTCG
AGTAGTTGAAAGGGTGCAAACGCCGTCGACACATTCACCGAATCGTTCTTGGTACTTTGACATGGAGAAC
TTTGTCGAGTTGGTCAGCAAACGGGCACAAAGTCTATTGAGCATTGCTATTACTCACCAGACCAGAACCT
TCAGAATTACTCCATCCGAAAATGACACCCGCCAAACTCTGGAAAAGACAGAGGGTCAAAGCCTTCTTGG
AACTCCTGGGGGCCATATTGAATAGTTGTGTCGATCAGTAGTGGTGTTTGTCTAGTAGAAGAGAAATGGA
TGCAATTGTAAATGAGTTATGAGTACGAAAAAAGTGGTTGTGGTCAAAATGCTACTTTAGTAAATCTGTT
ATCTAATGGATGTAAATAAGGTCGTCGTATCACAATATGAGTTTAAGAGGAGGTAATGGCGAGCAAAGTG
ATGACTTTGAGGTGGTGTGAGAAGTCAAGCTGTTGGAAAGTATCAAAGCTCCGCAAATGGGAATGTTTTT
CGCACTTGACGCCTTTATATATGAAATGAGGAGAGCTAATACTCGTCAGGAGTCCTAGAGAATAAAACTC
GTCTCCTTGGGGGTTCATGGGGAAACTTTTTCACTCATCGGGGTCGTCTAAGGAAAACGTGTAACGGCCC
CCGTC
Protein Sequence 
>gi|799336417|ref|XP_012051260.1| hexose transporter [Cryptococcus neoformans var. grubii H99]
MAPRSSKKALTLCLFQSLAGVIFGWSNSEGSGLFSMSKYQERFGECVDGVCTLSTTRQSAITGLLSVGAV
IGAVGSGSIADRFGLRLTCMVFIFIYLCGAAIETSAFNTYGQLCVARLLTGLGVGATSGLVPVFQAEASP
PRYRGLVTGSFQLCVTLGIWGVAMTNWGMSSYAGDVSWRIPVSLQMVWAALLLVGFLFSPESPRFLAKKG
RWEHCRKNLANLRGLPVDHPDIDTEMEEVREATIKDQERGQASYVECFSTKDRILWRTMIGICVQIGQQI
TGVNFFFSYGVQFAQTAGLDDTYVFQIILASVNVLFSFPGILAVDRAGRRPILLIGGILMFIGQIVVGAV
SKAYPDDKIAGDVLIAFTCLFIASFASSWGPIAWVVCGETFPIRLSSLCVTLGTGANWLFNLIIAFAAPQ
IQARIGTGITFVWAGCLAISVSFAFFCIPETRSMSIEQVDALYLSHTPAWRSHKFVDEQLARAQNAQEKH
YSRSIHAENEQVKSSQQTSARTSAEDDRIV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hxt1 mutant strain showed virulence similar to that of the wild-type strain in experiments with Caenorhabditis elegans (Chikamori and Fukushima, 2005).
References
Chikamori and Fukushima, 2005: Chikamori M, Fukushima K. A new hexose transporter from Cryptococcus neoformans: molecular cloning and structural and functional characterization. Fungal genetics and biology : FG & B. 2005; 42(7); 646-655. [PubMed: 15907385].