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GBP1

Victor ID 5311
Gene Name GBP1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23884994
NCBI Protein GI 799327999
Locus Tag CNAG_01262
Genbank Accession CP003824
Protein Accession XP_012049425
Taxonomy ID 235443
Chromosome No 5
Gene Starting Position 757759
Gene Ending Position 759242
Gene Strand (Orientation) -
Protein pI 6.77
Protein Weight 35705.04
Protein Length 352
DNA Sequence 
>gi|799350697:757759-759242 Cryptococcus neoformans var. grubii H99 chromosome 5, complete sequence
CACCATTATACTTTATCATGTAATGCATTACAAAAAATATATATATATCCATAAACAAAACGACCCATCC
ATCCGTACCTCTTTCCATAAACAGATATCATTATGGCACAATAAATCACCGTTCATAGCAACGCAATTAC
GACCAGACCTGGCGCGGCTTTCAGTCAGCCAAGCCACCTGTGTTGCATCCGTAATCCATGACTTACCTTG
AGCAAGCTATCCCAGCTGCCTGTACAAAGGGCCACACCATCTCCGGATACACCCATGCAGCTGACTCTAT
TTTCATGGCCTGCTAGGACGCCAATCCGTTCGCCCTTGAGGGTGTCCCAGACATTACAGTTGTAGTCATC
GTAGCCGGCAAAAAGCACACGACCCGAGATGGAGAAGGCGACGGATGTGATGCCGCAGAGGATATTATCG
TGGGCGTAGCTGTTGAGTTCACGGTCTGCGCGCAAGTCAAAGAGTTTGCATGAAGCGTCGTCGGACCCAG
TGGCAAAGGCGTCGCCGTTGGGGAAGAACCTAGACGGGGAATAAGCAATAAACAATAAGCATATGTGTTG
TGCTTACTGAACGGCGTTTATATCTGATTCGTGACCGGTAAATGTCTGGACGGCCTTGCCTGTTCTAATA
TCCCATACTTTGGCAGTGGCGTCGCACGCTCCAGACACAAACAGGTTGGCATTCGGGGCCAGAGAGATAC
TATGATCAAAATCAGCATAGACCCATATAGAAGAACGCGGTGGGCCCACCTCATCACATCGCCCGTATGG
TCGTTGAATTCCATGGTCCGCGTCCCCTGCTCAATGTCCCAGAGCATACACGTCATGTCGCCGGAAGAGG
TGACGATCTGCCTGTCGTTTATGAAGCGGCAGCAGCTGAGGTACCCGGAGTGTGCGCTGAGCTCTCTGGC
GACCTTGACCTGCCCGCCCGGCGCGCCCGGCGCGCCCGGCCCCGCTCCGCGCAGGGAGTAGATGGAGCAG
ACGTTGTCGAGGCCACCGCAGGCGACGAGGTTCCCGGAGGGGGCATAGGCGGCGGTCATGACCCAGGAGG
AGCGGAGTGGGATGGCGTGGACCTTGTTGGTGGTGTAGGCGTCCCAGACGATGAGCTTGCCGTCCTGGGA
GGCGGAGACGATGTGGCGGGTGTCGGCGGCCCAGTGGAGGGCGTAGATCTTGGCGAGGTGGCCCTTGAGC
GTGCGGCGGGCCTTGAGGGTGATGCGGGGGAGGGGGGGCGTGTCCGTCGCCATCGCGCGCACTGGCTGTC
AGCGGGGGGGGCGGGGGGGGACTCACGGCTTGTGTCGGCGGTCTGGTCCCGCGCCGCTCGCAGCTTGTCC
TTCAGACCGTCCGCCTCCCGCCGCGCGGCCGCGATCTTGTCCTGGATGTCCTGCATGGGGGGAGACTACG
AGGGGGGGGCGACGGAGGAATGGCAGCGAGAAATACACTTGTGGGGCCGATTGGACGCCGAAGGGTGGAG
GCCCGTGCGCATCC
Protein Sequence 
>gi|799327999|ref|XP_012049425.1| guanine nucleotide-binding protein subunit beta [Cryptococcus neoformans var. grubii H99]
MQDIQDKIAAARREADGLKDKLRAARDQTADTSLRAMATDTPPLPRITLKARRTLKGHLAKIYALHWAAD
TRHIVSASQDGKLIVWDAYTTNKVHAIPLRSSWVMTAAYAPSGNLVACGGLDNVCSIYSLRGAGPGAPGA
PGGQVKVARELSAHSGYLSCCRFINDRQIVTSSGDMTCMLWDIEQGTRTMEFNDHTGDVMSISLAPNANL
FVSGACDATAKVWDIRTGKAVQTFTGHESDINAVQFFPNGDAFATGSDDASCKLFDLRADRELNSYAHDN
ILCGITSVAFSISGRVLFAGYDDYNCNVWDTLKGERIGVLAGHENRVSCMGVSGDGVALCTGSWDSLLKV
WS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The gene encoding a heterotrimeric G-protein beta subunit. This gene is required for mating and haploid fruiting in Cryptococcus neoformans (Wang et al., 2000).
References
Wang et al., 2000: Wang P, Perfect JR, Heitman J. The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans. Molecular and cellular biology. 2000; 20(1); 352-362. [PubMed: 10594037].