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actA

Victor ID 531
Gene Name actA
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 987035
NCBI Protein GI 16802250
Locus Tag lmo0204
Genbank Accession AL591974
Protein Accession NP_463735
Other Database IDs UniProtKB-ID: ACTA_LISMO
UniRef100: UniRef100_P33379
UniRef90: UniRef90_P33379
UniRef50: UniRef50_P33379
UniParc: UPI0000001710
EMBL: M82881
EMBL: X59723
EMBL: AL591974
EMBL-CDS: AAA25269.1
EMBL-CDS: CAA42407.1
EMBL-CDS: CAD00731.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0204
GenoList: LMO0204
HOGENOM: HBG532808
OMA: SSFEFPP
ProtClustDB: CLSK226143
BioCyc: LMON169963:LMO0204-MONOMER
Taxonomy ID 169963
Gene Starting Position 209469
Gene Ending Position 211388
Gene Strand (Orientation) +
Protein Name actin-assembly inducing protein precursor
Protein pI 4.71
Protein Weight 68063.81
Protein Length 639
DNA Sequence 
>gi|16802048:209469-211388 Listeria monocytogenes EGD-e, complete genome
AGTGGGATTAAACAGATTTATGCGTGCGATGATGGTGGTTTTCATTACTGCCAATTGCATTACGATTAAC
CCCGACATAATATTTGCAGCGACAGATAGCGAAGATTCTAGTCTAAACACAGATGAATGGGAAGAAGAAA
AAACAGAAGAGCAACCAAGCGAGGTAAATACGGGACCAAGATACGAAACTGCACGTGAAGTAAGTTCACG
TGATATTAAAGAACTAGAAAAATCGAATAAAGTGAGAAATACGAACAAAGCAGACCTAATAGCAATGTTG
AAAGAAAAAGCAGAAAAAGGTCCAAATATCAATAATAACAACAGTGAACAAACTGAGAATGCGGCTATAA
ATGAAGAGGCTTCAGGAGCCGACCGACCAGCTATACAAGTGGAGCGTCGTCATCCAGGATTGCCATCGGA
TAGCGCAGCGGAAATTAAAAAAAGAAGGAAAGCCATAGCATCATCGGATAGTGAGCTTGAAAGCCTTACT
TATCCGGATAAACCAACAAAAGTAAATAAGAAAAAAGTGGCGAAAGAGTCAGTTGCGGATGCTTCTGAAA
GTGACTTAGATTCTAGCATGCAGTCAGCAGATGAGTCTTCACCACAACCTTTAAAAGCAAACCAACAACC
ATTTTTCCCTAAAGTATTTAAAAAAATAAAAGATGCGGGGAAATGGGTACGTGATAAAATCGACGAAAAT
CCTGAAGTAAAGAAAGCGATTGTTGATAAAAGTGCAGGGTTAATTGACCAATTATTAACCAAAAAGAAAA
GTGAAGAGGTAAATGCTTCGGACTTCCCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGA
GACACCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTCATTCGAATTTCCACCACCA
CCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACGCCAATGCTTCTTGGTTTTAATGCTCCTGCTA
CATCGGAACCGAGCTCGTTCGAATTTCCACCGCCTCCAACAGAAGATGAACTAGAAATCATCCGGGAAAC
AGCATCCTCGCTAGATTCTAGTTTTACAAGAGGGGATTTAGCTAGTTTGAGAAATGCTATTAATCGCCAT
AGTCAAAATTTCTCTGATTTCCCACCAATCCCAACAGAAGAAGAGTTGAACGGGAGAGGCGGTAGACCAA
CATCTGAAGAATTTAGTTCGCTGAATAGTGGTGATTTTACAGATGACGAAAACAGCGAGACAACAGAAGA
AGAAATTGATCGCCTAGCTGATTTAAGAGATAGAGGAACAGGAAAACACTCAAGAAATGCGGGTTTTTTA
CCATTAAATCCGTTTGCTAGCAGCCCGGTTCCTTCGTTAAGTCCAAAGGTATCGAAAATAAGCGCACCGG
CTCTGATAAGTGACATAACTAAAAAAACGCCATTTAAGAATCCATCACAGCCATTAAATGTGTTTAATAA
AAAAACTACAACGAAAACAGTGACTAAAAAACCAACCCCTGTAAAGACCGCACCAAAGCTAGCAGAACTT
CCTGCCACAAAACCACAAGAAACCGTACTTAGGGAAAATAAAACACCCTTTATAGAAAAACAAGCAGAAA
CAAACAAGCAGTCAATTAATATGCCGAGCCTACCAGTAATCCAAAAAGAAGCTACAGAGAGCGATAAAGA
GGAAATGAAACCACAAACCGAGGAAAAAATGGTAGAGGAAAGCGAATCAGCTAATAACGCAAACGGAAAA
AATCGTTCTGCTGGCATTGAAGAAGGAAAACTAATTGCTAAAAGTGCAGAAGACGAAAAAGCGAAGGAAG
AACCAGGGAACCATACGACGTTAATTCTTGCAATGTTAGCTATTGGCGTGTTCTCTTTAGGGGCGTTTAT
CAAAATTATTCAATTAAGAAAAAATAATTA
Protein Sequence 
>gi|16802250|ref|NP_463735.1| actin-assembly inducing protein precursor [Listeria monocytogenes EGD-e]
MGLNRFMRAMMVVFITANCITINPDIIFAATDSEDSSLNTDEWEEEKTEEQPSEVNTGPRYETAREVSSR
DIKELEKSNKVRNTNKADLIAMLKEKAEKGPNINNNNSEQTENAAINEEASGADRPAIQVERRHPGLPSD
SAAEIKKRRKAIASSDSELESLTYPDKPTKVNKKKVAKESVADASESDLDSSMQSADESSPQPLKANQQP
FFPKVFKKIKDAGKWVRDKIDENPEVKKAIVDKSAGLIDQLLTKKKSEEVNASDFPPPPTDEELRLALPE
TPMLLGFNAPATSEPSSFEFPPPPTDEELRLALPETPMLLGFNAPATSEPSSFEFPPPPTEDELEIIRET
ASSLDSSFTRGDLASLRNAINRHSQNFSDFPPIPTEEELNGRGGRPTSEEFSSLNSGDFTDDENSETTEE
EIDRLADLRDRGTGKHSRNAGFLPLNPFASSPVPSLSPKVSKISAPALISDITKKTPFKNPSQPLNVFNK
KTTTKTVTKKPTPVKTAPKLAELPATKPQETVLRENKTPFIEKQAETNKQSINMPSLPVIQKEATESDKE
EMKPQTEEKMVEESESANNANGKNRSAGIEEGKLIAKSAEDEKAKEEPGNHTTLILAMLAIGVFSLGAFI
KIIQLRKNN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant impaired in cell to cell spread, attenuated in maternal organs (Bakardjiev et al., 2005).
References
Bakardjiev et al., 2005: Bakardjiev AI, Stacy BA, Portnoy DA. Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection. The Journal of infectious diseases. 2005; 191(11); 1889-1897. [PubMed: 15871123].