Victors

GTA1
Victor ID	5307
Gene Name	GTA1
Sequence Strain (Species/Organism)	Cryptococcus neoformans var. grubii H99
NCBI Gene ID	23884053
NCBI Protein GI	799314302
Locus Tag	CNAG_00193
Genbank Accession	CP003820
Protein Accession	XP_012046597
Taxonomy ID	235443
Chromosome No	1
Gene Starting Position	521600
Gene Ending Position	527075
Gene Strand (Orientation)	-
Protein pI	9.06
Protein Weight	130038.91
Protein Length	1277
DNA Sequence	>gi\|799350543:521600-527075 Cryptococcus neoformans var. grubii H99 chromosome 1, complete sequence TAATAAACTTCGGAGCCAAAAAATGATACATTTCGATGATCAACGAGCGTCTTAAGTTTCCCCAAAACTC AACCCAAAAAAAAATCCAATAAACATTGTAATTGTATCAAACATATAAGAACCGAGCCTCTTTTTAGAGA CCCGGAGGCTTTAAGAATCCATACATGGTACCGTTGGATGCACGGACCTGAGAGTAGTTCAATGATATAA GTTTGAAAACAATACGATAAGTTTTAACCGAATAATATGGAAATGAAAAACATAAAAGCGGAACGTCAGG CGCAACCAGAGCCCGCTATGCGAGCGACAATACGCCTCTCCCCGAATCTCCACTCCCATTGCTTCCATTC ATTCGCTCATTCAACAAGAGCATCAGAAGCATGCCGTGCCTTCTTGCTTCCGCCACCGGAGTTTGCAGAG GATGCGATTGTTGGCGAGGTGGGCTTTGACCGCACAGACGTATTTTTTGATGAAGCGACACTGTTCTTGC GGGAAGGGTTGCTTTCTTTCGGTCCAGGACCCGCTCGGTTTCTACACGCCCTGATTAGATATTGCAATTC TCGCCGAATTGTAAACGCACCTTTTCTTAATAACATCCGTCTTGAGCGACAAGGGCCGAACGACGCCGTG CAATTTCTGATAGATCATTAGAGCATTCCAAATTATTTAGACGAAAACAGAGTATTCACATAGAAAAGTC CACACGCATTGCACAACGGTTGTCCATCTGGATCTCGTCTCCATAAAGGAGTGTTCGTGGTCTGACAATT CGTACACATTGTGGGGTTCTCACCAGTAGGCATGATAGAGCCTGGTCCGCCCTCATTTTCACTCGTTGGC GAACCTGGTCGAGACTTATTATTTCCATCTGATCCCTTGTTCCCTTTACTAGAACCAGACCCAGCATTTC CTGATGCATTAATTGAGGCAGTACGATCGTGTTTTGACGATCCGCTGGAAGACATTTTCAGAGCAGCAAG ATTAGGAGTACTATTAGACCTGTTCGGGGGTGGCATCTGTCTGTTGTCGACAGGCTTACCACCTACAGCT TTCGGTAATGGCCGGATATTGTTACCCGAGCTGTTATTACCAGGCGTAGGAGCACCGCTTTGGGGGGAGA TAGCACTGGGAGAGAATTCGTTGGCGGTCTGACTGGGCACAGCTCCAAGCACTTGGGAAGGATTGATGTG GGTAAACGGGCTCGCGGATGAGTTGGCATTGAGGTAGAGGTGCATGAGCTGCTGAAAATCAAAAGGATTG TCGCTTGTAGCTTGAGGCATTGAAGGAAGGGACATTCCTGGTTCGATGTGACCAAACCCCGAAGGAGAAC CAAAAGCTGATGTATCCGCTGTAACAGGTTGACTTGCCCAGTCTGTCAAGTCTGCAAGGTCGCCATCACC TCCATAGTTCACATCACTGTTTTCTTGAGTTCCTGAAGGAGTTGCACTCGCGGCAGCTAGGTCAAAGAAA TTCTCGTAGGACTGAGGGAAGCTGAAGGTGAATTTTGATGTGGGGAAGCCGCTGTCACCTTCTGGAAGAG GATTATTCGCGCCCCCTCGAGGAGAGGCTTCGGCATGGCGCTTGCGAGGGTTGGACATGGATTGGGGGGA GGTGGATGGCTCACCCTCTCCCAGCAATCTCACAGTGTGGTCGAAGGATGTCTTCCGCACACGACGAGGA AGAAATCCATATTGAGGATGGAAGTTTTCTTGGCTATGTGTATAGAGGCCTGGACCATTGATACCAGGCA AGTTAGACGTAGATCCCTTAGAAGGACTAAGCCCACTCGCGAGAGACATCTGAAGATGCTCCAGCGCGCT CCCGTTCTGAGGTGCGGAGGCGGGATACAAGTCAGTCCCATTGATGTGCTCGACAGCTTGCTGCACTTCA TCCTGCTCCCCTTCTTTCTCGGGTAGCTGACTCAAACTTTGCAGCATCATGCTAGAAGGACCAGGGAGAG ATGAAGCATGGTTATACTGATTCTGGCTACTATGATGGTTTGCCGAGTGGGCGTTAGCGGCGTGAGTGTT CAAACTACCGTGTCCGGCCATGTATTGGCCCATCTCTGCGATAGGTGTTCCGCCAGCAGCAAGAAGGTGA TGAGCGTGAGCTTCACTGAAGGGGTTGCGGAATGGAGCGGCAGAACGGGAACGTGACCTGGAAGAAGCGC GCCAGTCAATATCCATGGGTATGCGAGAACGGGATCGGCTTGCTGCTCGCCAGTCGACATCCATGCCGCT AATGAAAACAATCAGTAAATGACATCATTATGCTGATATGGTAACTCACTTTGGCGATTGAGAATTTGAA CTTGTTGCTCCAGCAAAACCAACGATCCTTGACTTTCCCTTTGTTCTTCCTCGTCTTTCCTCCACAGGAG GCAGTTCTGCAGCTGCCGCAGCCGTTGCTGCGGCTGCTGCTGCCGCTTCCTTCTCAGCAACCTCCTTCTC TTCTTTCTCTCTTTCTTCCTTCTCCTTTGCCGCTTGCTCCTCTTCCTTCTTCTTCAATGTAAGATGCATC ATTCTCCAAGTCAAATTCTCCATCCTCTGCCCGTTGGGCAAGGTATCCCTGGCTCTTGCGTATGCTTTCC AGACTTGCGCTGCAAGTGGATCCTTCTCAGCCATCTGCTCCGGAGGGCCAACCTCGGGTAATGGGCTTGT GGCATCGCTCTGAGATGGTCGACGTGTAACTGGGAAAGACCCAAAACTATTGAGTGGCGGGGTCATAAGA GGAGTGCTAGGAACGCGAACAGTGAGGAAGTCATCTTCAAGAATGTCGCTGACGATGTTTGTATCTTTCC GTCCCTTACTAGACGATGCTTCAGGAGATGACGCATTTTGAGAGAAGGACGGCGGAGGAGCACTCGTGGT AAGTGGCCAAGACGGGGAAGCAACATCAGCGGTTTGCTTCGCTTGCTGACCCAAGCCCATACCAATACCC ATGCCCATTCTCAAAGCCATTTCTAGACCTGCAGCTCCATACTGGGCAAGATGTTCAAGAGACAAACCGT TTGGCAAAGGAGGCAAGCCATTAAGCGAAACGCCGCCGGGCATGGGGCCGTCATGAGGAGCTTCAGAGCC GGCTCTCGAAGCATGCTCGGAGGATGGTACACCTCCCCGATGTGTCTGGAACACAGGAGCAGGATGCTGA GGTGCTTCCCGTCGACGTGGAGCAATGGGTGGATACCGCGAACTACTGCTTGAGCCTTGTAATTCATGTC TGGACATCAGTTCCTGCTGCCACGAGCCTGCAATACCCATCTCAAAGGGGTCGTTGACTCCGAAATCACT GCCGCCGGGTGTTGTCACCGGCGTCTCGCTCGAACCCATTGCGCCGTCGGCCAAAGGCCAAGGCGTCATG ACTTGACTAGATGCACCTTTACTCACCTTATCAGGCTGTGCAAAGGTGACATTATTGTACTGCTGCTGAG AGACAGGGAATCCAGATAGCCCCCCGGAATTGTGCAAGATGCCGGGAGAGTTAGCCGACGATTGATTGCG TGAGCGTATGTTCTGATCATGAGAGCTAGTCTGCTGTTGGTGCTGCAAGCGACGACTTAAAAGGCTTGTA CCTCCAGGATGTGAAATTGACTGGGCGGTGCCCCTAGCAGCTTTTGGAGACGTACTTGCGTTCAAAGCGC TCATAAAATCGATGGAAGCACTGTCGTCCATTTTACCCTGATTTTGCTGGACCAGATCAGCAAGACTGGC GAAAACAGCTGGATCGATGGGATCATCATTACCGGCAGTCTTTTGAACCGTGCCCAACGAAGAAAACCAG TTGGTGGGGTTCGGAAGAGATGTCCAGTCGAACGGCTTGCTATTCGAATCATTTTCACCCTGTCGACCAG GAAAAGATGTACCCCAAGAGGAAGGAGGAGGTTCTGCGGGAGTAGTGGATATCATGGGAGCAGAACGTTT TGATCTAGAAGAGGATAACTGAGAATGTGAAGAGGGTTGAACACTCTGGGAAAAGCTGTTTCGTGGAACG CTAGAACTCATTCCGACAATATCAATAGGAGTCATTGGGGTAGGAGTGGTGGCAATCGACGAATGGTCAT TACCATGGAAAGAACCACTGCCGCTGTGTCCTATGCTTGATGGCTGAGAGAATGATTGGTATCCCTGTGG AGGGTAAGGAAAGTTGTGCCGATTGATTGGAATGGAAGGCGACATGGCAGGTGTTGGAGGATTGGAGGGC CGGGAAGACGCGGCAGAAGGGGGTCGTTCTGGGACTCGAGCACTATTTACTTTCCCATTGTAAACGGCTT GTCCTCCCCCAGCGTCCACAGTGAACGGTCCTTTTTTTCCCCCCGATGTAGTGCGCCATGGAAGCTTGTC CATCCTAGCCGCCGCTAGCTGCTGTTTGGTCGCAGTGCTAACGGGTCGAGTAGACGGCTCGCGAGGCGCC GTTGGTTTCGGCAGAAGTGGACGAAGCCTAGAAGAAGTCCCGCCAGTGCTAGTTGAAGTAGTAGATACAG GGGACGACTTTGAAGATGTGACAGACCTAGGAGATGGGCCTATAACGGGTGGAGATGGGGTGGAAATGGT GTCGGTTTTGTGGCGTTGGTCGCTGTGGTAATTGGAAGTAGCGGGAAGACCCGCGATTCGTCGTTAGCTT GCAATCACCACAGATCAAAGCGAGAAGAAAGGTTAGAGGCCCCGAATGACTCCTTCCATAACAAGGCTTG GATGACAAAAGATGCGAAAGTGAAGCAAGTAAGATTCGGCACGAAAGTCAAGAGAGGGTCAGACGCCGTT TCAATAGGAGGCAAAGTTTTCACATCGACAATCGGCAACAGCCTTTATTCGCCTTTCTTGTGGGATTGAC GAGAAGCCCCACCGGTCCAGCGCTCGCCTTCGCAATTATGAGCTGACGAATATCCACTTGACTCCTTCGT GTTTTCGCGTATAAAATGCAAAAGGGGTCTGCTGGGAACGGAAAAGGGATATGGGTACTTACCTGATAGG AAGGAGGGGAGCTTGCAAGATCTCCTCTACTGCAGTCTATGGTGTGGTAACGGGCTGCAATCTACAATTG CGGGATTGGTTAGGGGTGAATAAAAATTGTTGACGGATGGAATGCCTCCAGTATTATTGTTGACTCGACG CCGGAAGCTCGGTTGGTGGGACGGTGGTGTGCTGGCGGGATAGTGGCAGCGGGAGCAGATTGTGGGATAA ATGGATGGGGAAGAAGTGTGTGGTGAATGGCTGGGTGAGTGAGCAAGGAATATACCGTGGGGGAGAGAGC GAAGAATAATTACTGCCTGCGAGCCACGGACCACATCCACAGCCACCACAAGGCCATTTCACCAGCATCC CGCAACCAGGCCCGATTTCTTACCCCTTGACTTGCGGCGGATTATTTATTGCCAAATACAGTAATTTCCT CATATCACTTTCACAGGCCGCCTCTCCTCCGCCGCCTGCCAACTATTTCTGCCCTGCCCTTTCCCTTTTC CGCCTCGTTCCTTATC
Protein Sequence	>gi\|799314302\|ref\|XP_012046597.1\| GATA type zinc finger protein asd-4 [Cryptococcus neoformans var. grubii H99] MDKLPWRTTSGGKKGPFTVDAGGGQAVYNGKVNSARVPERPPSAASSRPSNPPTPAMSPSIPINRHNFPY PPQGYQSFSQPSSIGHSGSGSFHGNDHSSIATTPTPMTPIDIVGMSSSVPRNSFSQSVQPSSHSQLSSSR SKRSAPMISTTPAEPPPSSWGTSFPGRQGENDSNSKPFDWTSLPNPTNWFSSLGTVQKTAGNDDPIDPAV FASLADLVQQNQGKMDDSASIDFMSALNASTSPKAARGTAQSISHPGGTSLLSRRLQHQQQTSSHDQNIR SRNQSSANSPGILHNSGGLSGFPVSQQQYNNVTFAQPDKVSKGASSQVMTPWPLADGAMGSSETPVTTPG GSDFGVNDPFEMGIAGSWQQELMSRHELQGSSSSSRYPPIAPRRREAPQHPAPVFQTHRGGVPSSEHASR AGSEAPHDGPMPGGVSLNGLPPLPNGLSLEHLAQYGAAGLEMALRMGMGIGMGLGQQAKQTADVASPSWP LTTSAPPPSFSQNASSPEASSSKGRKDTNIVSDILEDDFLTVRVPSTPLMTPPLNSFGSFPVTRRPSQSD ATSPLPEVGPPEQMAEKDPLAAQVWKAYARARDTLPNGQRMENLTWRMMHLTLKKKEEEQAAKEKEEREK EEKEVAEKEAAAAAAATAAAAAELPPVEERRGRTKGKSRIVGFAGATSSNSQSPNGMDVDWRAASRSRSR IPMDIDWRASSRSRSRSAAPFRNPFSEAHAHHLLAAGGTPIAEMGQYMAGHGSLNTHAANAHSANHHSSQ NQYNHASSLPGPSSMMLQSLSQLPEKEGEQDEVQQAVEHINGTDLYPASAPQNGSALEHLQMSLASGLSP SKGSTSNLPGINGPGLYTHSQENFHPQYGFLPRRVRKTSFDHTVRLLGEGEPSTSPQSMSNPRKRHAEAS PRGGANNPLPEGDSGFPTSKFTFSFPQSYENFFDLAAASATPSGTQENSDVNYGGDGDLADLTDWASQPV TADTSAFGSPSGFGHIEPGMSLPSMPQATSDNPFDFQQLMHLYLNANSSASPFTHINPSQVLGAVPSQTA NEFSPSAISPQSGAPTPGNNSSGNNIRPLPKAVGGKPVDNRQMPPPNRSNSTPNLAALKMSSSGSSKHDR TASINASGNAGSGSSKGNKGSDGNNKSRPGSPTSENEGGPGSIMPTGENPTMCTNCQTTNTPLWRRDPDG QPLCNACGLFYKLHGVVRPLSLKTDVIKKRNRAGPGPKESNPSRKNSVASSKNTSVRSKPTSPTIASSAN SGGGSKKARHASDALVE
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: The gta1 mutant exhibited impaired growth on all amino acids tested as sole nitrogen sources, with the exception of arginine and proline. Gat1 is not required for C. neoformans survival during macrophage infection or for virulence in a mouse model of cryptococcosis (Kmetzsch et al., 2011; Kmetzsch et al., 2011).
References	*Kmetzsch et al., 2011:* Kmetzsch L, Staats CC, Simon E, Fonseca FL, Oliveira DL, Joffe LS, Rodrigues J, LourenÃƒÂ§o RF, Gomes SL, Nimrichter L, Rodrigues ML, Schrank A, Vainstein MH. The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans. Fungal genetics and biology : FG & B. 2011; 48(2); 192-199. [PubMed: 20673806].


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GTA1