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CPA1

Victor ID 5294
Gene Name CPA1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23883998
NCBI Protein GI 799314095
Locus Tag CNAG_00135
Genbank Accession CP003820
Protein Accession XP_012046553
Taxonomy ID 235443
Chromosome No 1
Gene Starting Position 367890
Gene Ending Position 368535
Gene Strand (Orientation) +
Protein pI 4.44
Protein Weight 14869.14
Protein Length 137
DNA Sequence 
>gi|799350543:367890-368535 Cryptococcus neoformans var. grubii H99 chromosome 1, complete sequence
GTACATCTACTCTTTCGTCATTATCCGCCGGTAAATCGAAAATAATGAACAAGACCACAGATCAGGCAGC
GTCCTCAAATCTCAACAAGAAGTCCTCAGTTTACGTCTCAGGCTTTGCTCCAGAGGTCGACGAAGAGCAA
CTCTTACAAGCCTTTGTTACTTTTGGAGATATCATCGAGATTAAGATTCCTCATGAGCCTCATGACCGTA
CGTCCTATGTACCAATCGTATAAATGCAACTTGGTGTTAACTGACTATCATGACAGCTAAAAAGCACCGC
GGTTACGCGTTCATAACCTTTTCCTCCGCTGCCGATGCTCAAGAAGCTATTGACAATTATGATCTCAATC
AATTACCGGGGTATCAAGGAAGCGGTAGATTCTTGAAATGCAGCTTGGCTCAGCCTAGCAAGTATGTGGA
TGAGAGTGGAAGGAACGATCGAGCAAGTGAGTGGAGCTGTTTTTGTTCAAAATAAGGCAAGAAGACTAAC
ATGATTATTGCAGTTTGGGAGACAGAGGAATGGAAAGCAGAACATGGAGAACGGCCAGAAGACGGACAGG
AAGCTACCGAATAAGGGCAATACCATGTATAATCATACCATTGTTGTACATCCATCGTGTTCACGAGAAA
TACTGAATCGCATTGC
Protein Sequence 
>gi|799314095|ref|XP_012046553.1| cyclophilin [Cryptococcus neoformans var. grubii H99]
MNKTTDQAASSNLNKKSSVYVSGFAPEVDEEQLLQAFVTFGDIIEIKIPHEPHDPKKHRGYAFITFSSAA
DAQEAIDNYDLNQLPGYQGSGRFLKCSLAQPSKYVDESGRNDRAIWETEEWKAEHGERPEDGQEATE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The cpa1 mutant is inviable at 39℃ and attenuated for virulence (Wang et al., 2001).
References
Wang et al., 2001: Wang P, Cardenas ME, Cox GM, Perfect JR, Heitman J. Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans. EMBO reports. 2001; 2(6); 511-518. [PubMed: 11415984].