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CnMT1

Victor ID 5293
Gene Name CnMT1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23888764
NCBI Protein GI 799347653
Locus Tag CNAG_05449
Genbank Accession CP003833
Protein Accession XP_012053609
Taxonomy ID 235443
Chromosome No 14
Gene Starting Position 341045
Gene Ending Position 342989
Gene Strand (Orientation) +
Protein pI 7.88
Protein Weight 11690.56
Protein Length 122
DNA Sequence 
>gi|799350995:341045-342989 Cryptococcus neoformans var. grubii H99 chromosome 14, complete sequence
GCAACACTGCAATCTATTAGTAATCCGCTTTATTTTCTTTTATTCCGAAGCGCATATCTATCTCATATCT
TTGATGCGTTGTGCCTGATGGGCCAAGTCGCTTGCTCCTTTCATTATTATCGTTATCCTATACGTCACCA
AAGCACAATTACCGCAACTTTGACCAGCAGACCTTTGCCACCTGCTGCCTATATAAACAGCAATCCAGAA
GCTGTCTAAAATTCATATCCGCAATCACTTAACACTTTTACAGAACACATCTGCATCCGATATACAACTC
AAACAAACTACAATCATGGCGTGAGTCCCGCTGTCGCTTCTCCCGTTATCCTGTTAAACAACAGCTCACA
AACTTCGTCCCTGCAGTTGCAACTGCCCTCCCCAGAAGAATACCGCTTGCTGCTCGTAAGCACATTTCAT
CACATGCACCGTTTAGAAGCCCTTCAAGACTAATGTACATGGTGCAGTACGAGCGAGGCTCAAGACAAGT
GCACTTGCCAGAAGGGTAACTGCGAATGCAAAGCCTGCCCAAATTCCACTAAAACTTCCGAGTCTGGCGG
AAAGGCCAGCACTTGCAAGTAAGTAATGCTCGTCAAAGAGCTTGTGAATAGATAGGAATTGACGGCGTTT
TGCATAGCTGCGGTGGATCTGGTGAGGCTTGTACATGCCCTCCAGGCCAATGTGCCTGTGACAAGTGCCC
TAAAAAGGCGAAGAGCGTGAGCACATGCGGGTAAGTCCTTTTCCTAGTCTTACAACGAACGAGCGAACTC
GTCGAGCTGGTTGCGACCAAGGGCAGTCAGTCGCCAGCAAAGGGGCATCGGGGATGGTCGATGATGAAGA
GATTTTAGAGATTTTAGACAATGCCATCAGTTATTGAGCAGATACTAATCGAATTCCATATAGGTGCGGT
GGCTCTGGCGCGGCCTGCTCTTGTCCGCCTGGCAAGTGTGCATGTGACAACTGCCCCAAGCAGGCTCAAG
AGAAAGTCAGCTCCTGCGCGTAAGTCTCAAGTCTGTTCTGACCGCTGTTCATGACAGGTGCTTACGTGCC
GAACAATTAGTTGCAGCGGATCTGGCGCTGCCTGAGCTTGTCTTCCAGACCAATGCTCCTGTGATAATTG
TTTGACCATGGCCAAATGAACTCAGGGGGGGCAAGGGATAGGATGAATCTTTGTTTCAATTGTACATTAG
TCACTAATCATGGTGAGGGCAAAAAGGGGGGCCCTTAGTGACATGCACGCATATTGTTGTGTTGATACAT
GATTCGGTTTGCGCAAGACCAGTTTTCCTTCAGGAGATCATTATAAGTAGGAGATTTACGCTACAATAGA
CGTGAAAAGTCAAATGACGTTTACCCTTTTCAGCTCTGACCGGCAGGAAGGCCTTGTGTTCAAACTTTGG
GGTTTCGATTGGGATTTTTGCAAACTAAGGAAAAAGGCTTCGAGTGGCAGGGAACATTGATTTAGCCATT
CAACGTTAGTCTGCATGTTCATTTGATATTACAAGAATTGTTAATAATCAACATGACCGAAGTCCCAAGT
TTTGATACACATTCCAAAATCTGCTGTCGCGTGCGCTGGGGGTAAATGCGCTTGACCATCGTCGTACACG
ATTCCGCCACCATCTTGCTCACCCAGGGCCCAATATACCAGGTAAATCTTTGTGTCGTCCATTTGAAGAC
AGGATGAATGCTTTAGCCCATTGGTATGGACGTCAAGAAGCGAGAGGATGCGTATGCCGGGCCAATTCCC
GTCAGCGAAATAGGACGATGACACATTGTAAGGCGGTGGAGGTAAGGATGAGGCATCGAGGAGATAAACC
TCAGACGTCTGGAAAGGCAGTGAGTAAATAAATTATGGCATGGGCGTTGTATGGCAGACCCACTGTATTG
AACACCACCCGTTCTCCGTTAGTATAGAGCTGGTTGATTGGGCTCTTGACCCTAA
Protein Sequence 
>gi|799347653|ref|XP_012053609.1| hypothetical protein CNAG_05449 [Cryptococcus neoformans var. grubii H99]
MACNCPPQKNTACCSTSEAQDKCTCQKGNCECKACPNSTKTSESGGKASTCNCGGSGEACTCPPGQCACD
KCPKKAKSVSTCGCGGSGAACSCPPGKCACDNCPKQAQEKVSSCACSGSGAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The CnMT1 was identified as one of the metallothioneins (MTs) and played an essential role in C. neoformans copper resistance (Palacios et al., 2014).
References
Palacios et al., 2014: Palacios Ò, Espart A, Espín J, Ding C, Thiele DJ, Atrian S, Capdevila M. Full characterization of the Cu-, Zn-, and Cd-binding properties of CnMT1 and CnMT2, two metallothioneins of the pathogenic fungus Cryptococcus neoformans acting as virulence factors. Metallomics : integrated biometal science. 2014; 6(2); 279-291. [PubMed: 24317230].