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CHI2

Victor ID 5286
Gene Name CHI2
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23886920
NCBI Protein GI 799336363
Locus Tag CNAG_03412
Genbank Accession CP003827
Protein Accession XP_012051242
Taxonomy ID 235443
Chromosome No 8
Gene Starting Position 887975
Gene Ending Position 890565
Gene Strand (Orientation) -
Protein pI 6.15
Protein Weight 48082.52
Protein Length 452
DNA Sequence 
>gi|799350780:887975-890565 Cryptococcus neoformans var. grubii H99 chromosome 8, complete sequence
CGGAAGTCACTCCTAGCAATATAGCAGCATCCCGACTTCCATTCCAGACTTAGGTTGTTCTTTTAAAGAT
GTATGCATGGTCTCTACATGGTTGTGACCATGAACATGCATAAGTATAGACAAAAGTTTTTGCTATACGC
AAGAAAATGTTCTTCTAAAATTTCAATATCATGCTACAGTTGTATAATTCATTCATCTTACTCCATCCTT
CTCCTCAAATTGTCGTATTCTGATCCCAGTCAGCAAAAGTCGTGCCCACCATTGTATATCTCAAAAACTC
ACTGCTTCCAGGATAATCCAACTCATTCTCCCTCCACTCCAGTTGACCCAGCGCTTCTCTCACAGTCCTC
ACCAATGACTGTCCTGTTTCTTCAGGCTTGTCAGAGTCCAGCTCCCACCACATTGCACCGCCCAGGCCGT
GATAAGCAATGTATGAAGCTTTCTGATGGGCGATTGCTTGGGTATCATAGGTAATGAGGAGACGCTTCGC
CCTAAGAAATAGTCAGCTGCGTTGTTGAGATAGAAGGATCATGGGATCTTACGGATCGTAGCTGTATGAA
GCACCGAGACGGTGGTCATTGGTTTCTTGGGCACCGGGCTGAGGCAGGGCTTTATAGTCCCACATACCAG
CCTCCCACGACCCTTCCCCGGTACCTGAGAAAGGCGAACCAATTCCTTTGGTGTTGGCGAAAGCACGTCC
ATAGACGGGCAAACCTGTGTATTTCGTCAGTTTCGTACGTGGTGTAAGGAAGATCAGACATACCAATGAC
GAGCTTGGTAGGATGCACACCAGCCTCCAGGTAGAATCGCACCGATCGATCAACAGACTGTCCGTCGGGC
TTGTCGGAGTAAAGGTTGGCTTGGTGACCTGCCACAGAGTCCCACGAGCCGGCAAACTACGACCAAAACA
CGATAAGGATATAGGTTTCAAGATTTTGCCGAGAAACTTACATCGTATGCCATCAAATTCCAGAAATCCA
ACACCTACTCTACATTAGCGACTGATCTTTCTGTGGATGATATACGGTTGAGGCCCACCTGGTCCATCTC
TCTCACTCTCAGAACTTGCATCTGTTCCCAGCCACAAGGAGCAGCGACAGTAAGCTGATACTGCCCCTGA
GGCTTGCCCTTACTTTGAGCGAGTTGCTCAAGTCCCTGTCGAAGTTCGCGGAGCAGATCGACATAGGCTT
CGGCGTCGCGGGGAGTCTTGGGGTATTCGTAATCAATCTTCAATAGGGTCAGTAAGAAGCCACCAGGTGT
CTGTCAACTTGATACCTACATCGAGGCTATGGGCGATGTCAGCAGACAGTACAGGATCAGAAGCCTTTAA
AGTCTCACCCGTCCAGACCGACATCCTCCACGAGCTTCACAGCAGATTGCACGAACGTTGATCGCCATTT
GGGGTGTACGATGCCCGCAAAATTCTATGTATAGATTAGATTGAGAACAATATGGGAGTATATGGAGAAC
ATGGCACTTACAGGGGAGAAAGACCATCCACCAATGGAGAGCAGCACCTTCAAGTTGCTGAATATGGTAT
TAGCTCAAGTCTTTTAACAAGATGAGCTCTTTACCGGTTCTGCTTCTTCATAAGATAGATAGCCTTGAAG
CAGCCATAGAGATTGGTACCAGGTTCATCCCACGAATCACCATCGTAGTGGATCTTGTACACAACATGAG
CACCTTGCATGCATCAAACTGGGCGAATCACTCACTTCGACGTCAGCCCAAGTGTCACTCAATACAACTT
CACCGCTATCCGCCTTCACATTTCCAAAGGCATAGTTAATATGGGTGAGGTGCTGACCAGGGATATTTTG
AGGGAAAAATTTGCGACCATAGATGCCCCTGGAGACCTGCAAGTCAGCGAATCTGCCAGGCCAAGATCAC
ATGAGAGAGATCTGACCAGTTCACCTGCGTGAGGTCGTTAGCTGTCGCTCCTTGCACAGAGTAGGGGATC
ACCTACAAAGTAGCCAACAGTACGCTTAGGATTGTTCATTTCTATTTCATCACCTTTGAGTGGCTCTTCA
ACAGCTTTCCAGGGACGTGATGGGAATGCGAAATCAGTCTGTGCGAAGAGGAAGACGATAGCAGCTAGAA
GGAGGACAGCTAGGAAAGCAAGACTGGCTTTGGATGTGGGTTTCTTGTCCGAGGAAGGATGCCGGGCTGG
TTTCGGGGAATGGGCCATAAGAAAAGAGTCAAGATGGCAGATGTATGAGTGGACGATTGTGGACAGCGGT
GCGGGACAACAAGCAAGAGACGACGTTTGCCGATGTGGGGCCCCAAACCATTCCGGCCAGAACGCCCACC
AAGAAACGGCCTTCCTACGTGCACAAGCGGAAAGAGTGCAAAACACAAACCTTTATCACATACAATATAG
CCGCACTCAACTCACCCGCATCATCAAGGCCTGTCAACATTCGCAATAACTTGCAAGACTGTCAATGGAT
CGAGCCATACAACCGGTATTTATCGCTCCCCTCTGTTATTCGATCTTCAACTTCCCCATCCTCACATGCA
GCATCTAAAGCCGGCACAGGTTACGGTACTGCAATGCTGTGCGCATTCTTTCCTGATTGCTACTACTTGT
T
Protein Sequence 
>gi|799336363|ref|XP_012051242.1| chitinase [Cryptococcus neoformans var. grubii H99]
MAHSPKPARHPSSDKKPTSKASLAFLAVLLLAAIVFLFAQTDFAFPSRPWKAVEEPLKGDEIEMNNPKRT
VGYFVNWGIYGRKFFPQNIPGQHLTHINYAFGNVKADSGEVVLSDTWADVEIHYDGDSWDEPGTNLYGCF
KAIYLMKKQNRNLKVLLSIGGWSFSPNFAGIVHPKWRSTFVQSAVKLVEDVGLDGLDIDYEYPKTPRDAE
AYVDLLRELRQGLEQLAQSKGKPQGQYQLTVAAPCGWEQMQVLRVREMDQVLDFWNLMAYDFAGSWDSVA
GHQANLYSDKPDGQSVDRSVRFYLEAGVHPTKLVIGLPVYGRAFANTKGIGSPFSGTGEGSWEAGMWDYK
ALPQPGAQETNDHRLGASYSYDPAKRLLITYDTQAIAHQKASYIAYHGLGGAMWWELDSDKPEETGQSLV
RTVREALGQLEWRENELDYPGSKYDNLRRRME
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: This gene encodes one of endochitinases of Cryptococcus neoformans and involved in sexual reproduction (Baker et al., 2009).
References
Baker et al., 2009: Baker LG, Specht CA, Lodge JK. Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans. Eukaryotic cell. 2009; 8(11); 1692-1705. [PubMed: 19734369].