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CCC1

Victor ID 5280
Gene Name CCC1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23889467
NCBI Protein GI 799345039
Locus Tag CNAG_06241
Genbank Accession CP003831
Protein Accession XP_012053059
Taxonomy ID 235443
Chromosome No 12
Gene Starting Position 710637
Gene Ending Position 713482
Gene Strand (Orientation) -
Protein pI 4.42
Protein Weight 65704.81
Protein Length 640
Protein Note (Dumesic et al., 2015)This gene belongs to the polycomb system that assembles repressive subtelomeric domains of H3K27 methylation (H3K27me) in the yeast Cryptococcus neoformans.
DNA Sequence 
>gi|799350913:710637-713482 Cryptococcus neoformans var. grubii H99 chromosome 12, complete sequence
ATTTCTGAGCGGAATAATAGTATAGCATTATGATCATAATATAGTGCATCGTCCCAACGAAATCTAAAAA
CCAAAAGGAATGCTACATTACACTTTGACATCAGTCTTCAAGACCTTCTTCCAAACCGGCACCTTTGCCT
TTTTCCTTTCCACTTCCCTCTTTATCTCCTCCTCCAACTCTTCCTCATCCAACTCTCCAGACGCATACCA
GACAATTGTCGCTATACCCAAGAGCGCGGCGATGATACATCCAGCAAGCGCGCCAATCGCCTTTGGTGTC
CAACCCATCTTGAGCGGCCAAGGTCCCCATGGCTGGCCGGCGAAATCGGTAGTAGAGAATTTGCCGACGA
CGTTACCCTCAGTACCCTTGTGCCACCATCTGCATTGATCAGTGATCTGCTCAGGAACGGAGGAAGCGAG
GGCTTGGAATGCTTCGGGGGCTTCGATCATGACAGCTGCGAGACCGGAGGAGAGATGCCAGTCGATCTGT
TAAAAGAAATTAACCGCGAGAAGCATCTGTCAGCCCAAGAAAACCTGAAAATTTTTACCAGTGAAGGGAA
GAAATGAAAGGACGTACATGACAGTGGAACATCCAAGTACCGGGGTTATCAGCTCTGAAACGGAGTACGA
CCTTGCCAGTTGGAGGAACGACGATTGTGTCACGTCGAGCGGGGTTAGTCTGGGATTCGTTAAGAGGAGG
ATTGATATCGGTGTCGTTGGAAGTGACGTCGAATGATTTGCTGACAACTTGGAATACGTGGCTGTTTCAA
TTCAATGATGTTAGCATATGTCCGATCAACCAGTTCAAAGGGAAAAAGGGAAAAGGGGAACAAGGGAGAG
AAAAGGGACGTACCCATGGAGATGGAAAGGGTGGAAACCTGCATCCCAGTTGTATACTGTAAGCTGAACA
ATTGACATATGTCGGTATGTGAAGGCATTAGTCATTGCTCCGTAAACGGCGGCGTCGAATGAGTCGTTGC
CCATAGTGAGGGCGGTAAGCATGGATGGGGTGGACGTGGGCATTTGGTAGGTAATATTATTGAACGAGGC
TCGGTTGGTTCCATCATCGTACGTCTGTTCAAGTTCAAATTGTGAGTCAGAACCTGGTCTAGTACGTCAT
GACGGAAGATTGGGTAAACGGAGTTTGAGGTGGGAGGCACGTACGTCAAAGTAGGCGTGAAGGTCAATCT
CAACATCCGGGTCACCGAGGATATCTTCCTGCACAATAGGGTCCAACTTGGTATCGTCGAAAGTGGGGAA
ATCATCTAGGATGTAAGGGGTAGCAGGTGGAGCGGAAGAGTTGTAAACGATTTGGATGGTGTTGTTGAGA
ACAAGATCGTCGGGGACGACGTCGTACCTATTTGGCGGAAGAGAGGTGTAAATGGTTAGCGCGGTGTGCT
TTCAGGAAAGCAAAGGGGGAGGGAAACGAGGGAACGCGTACATATCGGTATCCTGAACGAACATGAACGC
ATAGTTTCTATCCGTTTGGTTCAGGGCTCGAACCCAAATGGAGTATCTTTGCGCGACCGATATGGAGACG
GCATCAACAGGGTACGGTGCGACTTCGACACCGTCCATTTCAATAATGTACATTTCATGACCTTCCAAAG
CCGCCCAGAACACTGTACAACGTGAGATATATTCAGCTACCTTGAAACATGGATAAGAGGGGGATATGTT
GTAAGGGTACTTACTGGCGAGGGTACCCATGTTGATCATGCGGATTCGGTAGGACTTTCCAGCCTCGAAG
TAAAGGGACAGACCGTCGCTAACACCCTCACCAGCGGAGATTTCCTCGTTCGTGCTCATATAGGTTCCGT
TCTGATAAGCGGCATAGATAACAGCTGAGTCTATTGTGGCAAAACAAAAGAGAGGACGGTCATTAGTTAT
TACCGTCTTTAGAAGGAAAATCGAAGGAATGAAGGACATACTTGGGACAGGTTCGGCACCGGTGGGGTTC
TTCCAGGTGAGGAAGTCACGTTGTTCGAGAACGGGATACTCTTCGTGATACCTAGCTCAAGGTCAGCCTT
TATATACCAAAATGATTAAAAAGGGGAAGAAAACTTGCCAGTCAGCAGCGGTAACGATATACTCGACATC
CCACGTAACATTATCCGTTCGACCAGTCCCATTCTGTGGGAAAATCACAACAGGTGATCGTAGACCATCG
GTATTCTGTCCATCAAGATGACCGTGAATCCAATAAGTGCCGACTTGAACAGTTGTATCGATTGTGTAGT
CGAGTGTCTGGCCATTGGGAATGGGACATTGGTTGACACCGACAGCACCGTCGTACCAGTTGGAGTGGTT
GAAGAACATGCCGTGAGAATGAAGGGATGTACCGACGGCGTCGTCGTCTAGGCTGTTGGTTGCGTGAACG
ATGATCACATCGCCTTGGGTGGCTGTCAAGACAGGTGGGCTATGAGAAGTTAAGCGGATCGTTGTCCGAG
AAGACAGGTCAGACGTACGGCCATGTTCCATTGACACCAATCACACGACGTTCGTGAAGCTGAAATTGAA
TGTTGGTCAGTCGATAAAAAAGAGCTTTTCCGAACCGAGTTGAAAGAACGACTTACCCCGTCTGGGTTGG
CGTTGCTATAGGTGATGTTCCACCAGTGCTCGTGAGTAGCAGCACGAGCAGCTGTAGCTGCGACTGAAAG
CGCAGAAGTTAGCAGAGCTGTAGTCGAGTACATCTTGCGTAGCGACAGGCAGCGTAAAGGACGGACGCTG
AAAGGAGAAGAAACTGGCTCTGTCTGAAGATAAATACATTCTCTATCCAATCTTTGTGCCAAGAATGGAA
AGATGCTTCATTGGGCCAGAAGCGGCAGGGGTCAAAAAATGCCTCA
Protein Sequence 
>gi|799345039|ref|XP_012053059.1| acidic laccase [Cryptococcus neoformans var. grubii H99]
MYSTTALLTSALSVAATAARAATHEHWWNITYSNANPDGLHERRVIGVNGTWPPPVLTATQGDVIIVHAT
NSLDDDAVGTSLHSHGMFFNHSNWYDGAVGVNQCPIPNGQTLDYTIDTTVQVGTYWIHGHLDGQNTDGLR
SPVVIFPQNGTGRTDNVTWDVEYIVTAADWYHEEYPVLEQRDFLTWKNPTGAEPVPNSAVIYAAYQNGTY
MSTNEEISAGEGVSDGLSLYFEAGKSYRIRMINMGTLAMFWAALEGHEMYIIEMDGVEVAPYPVDAVSIS
VAQRYSIWVRALNQTDRNYAFMFVQDTDMYDVVPDDLVLNNTIQIVYNSSAPPATPYILDDFPTFDDTKL
DPIVQEDILGDPDVEIDLHAYFDTYDDGTNRASFNNITYQMPTSTPSMLTALTMGNDSFDAAVYGAMTNA
FTYRHMSIVQLTVYNWDAGFHPFHLHGHVFQVVSKSFDVTSNDTDINPPLNESQTNPARRDTIVVPPTGK
VVLRFRADNPGTWMFHCHIDWHLSSGLAAVMIEAPEAFQALASSVPEQITDQCRWWHKGTEGNVVGKFST
TDFAGQPWGPWPLKMGWTPKAIGALAGCIIAALLGIATIVWYASGELDEEELEEEIKREVERKKAKVPVW
KKVLKTDVKV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: This gene belongs to the polycomb system that assembles repressive subtelomeric domains of H3K27 methylation (H3K27me) in the yeast Cryptococcus neoformans(Dumesic et al., 2015).
References
Dumesic et al., 2015: Dumesic PA, Homer CM, Moresco JJ, Pack LR, Shanle EK, Coyle SM, Strahl BD, Fujimori DG, Yates JR 3rd, Madhani HD. Product binding enforces the genomic specificity of a yeast polycomb repressive complex. Cell. 2015; 160(1-2); 204-218. [PubMed: 25533783 ].