Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

CAT1

Victor ID 5278
Gene Name CAT1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Gene ID 23888371
NCBI Protein GI 799324461
Locus Tag CNAG_05015
Genbank Accession CP003823
Protein Accession XP_012048657
Taxonomy ID 235443
Chromosome No 4
Gene Starting Position 229870
Gene Ending Position 232835
Gene Strand (Orientation) +
Protein pI 8.23
Protein Weight 73312.21
Protein Length 701
DNA Sequence 
>gi|799350666:229870-232835 Cryptococcus neoformans var. grubii H99 chromosome 4, complete sequence
TCTTCAGTCAGCAAATCTCCCATGGTCCACTACCTTTTGTTGCCGTCGAAAATACCGTAATTTCCTGTGT
GCTCGCTTTGATGGCATGCTGACCAATTGCACGAATTATGAAACCTCAATAACCGCGGCCAGGCGCATCT
AGATATGGAGCGTTAACTGGCGGTTGGCGCTTGGGCGGCTGTGAACAGCTTCGTTCGACCACTTATCTTT
TGCCTAAACTCATCCATCTGATACGTGACCTCGACAATTAGAATGGTACATATTTGGAATATGACATGCA
CCCCGGGCTCTCCTTCCCCATCCCCCTGCTTATTGCAATCCGCCATCCCTCTATCTCTGTCATTCTCATT
AACCCGATATGTCTGCTCGTAACCTTGCCTCTGGTACTCCGTACGGCAAGAATCTACCGACAGCCAACGG
TACACACTTCGAAGCTCCGTCAATATCTTCTACCTCCGACTCAGTTAATTCGGCGTATTCGGTTGGCTAC
ACTCCTGTGCCAACTGCGGAGCGTTCCTATTCCGGTTTACTTCACGGCACGCTATCCAAAGTATTTCGCA
AGGGCGGTCAAGAAATCGTCGTATCTGAAGAGCCTGTGTCTTTCAACTCTTCCAAGGCTGACACTGAATC
TACTCGCTTCAATGGATGTCCTTACATGAACGGCAGTATCCCTCAGACTCCGACACCAAAGTCGACGCCC
AAATCAGCTTCAGTGGCCGCCCCTGTTCCTTTGCCCCCTCCCTCGGCTGCGCGTCTGAAGGCCCAAAAGC
AGAATAATTCAATACCTCGAGATAATAGCAACACTCTGGCGGACGATGTGGGAAAGTTGACTGTTCGATC
ATACGAGAAGGATAGGGACCTTAGGTCCCAGGAGGTGTACGTACTAAGATCCCCCCTTTTGTGACTTCCC
CGACTGACAAACACCTCAAAGTATCTATACTACATCCAACGGTGTTCCGGTCCCCCACCCATATGTTGTT
CAGCGGGCTGGTGTTAACGGTCCCCTTCTTCTGCAAGACTTCCACTTGATCGACTTACTCTCTCACTTTG
ATCGCGAAAGGTGAGCCCGATCATTACTTGATTCCTAAATCTTGAGGACTGACTTTTGCATAGGATCCCT
GAACGAGTGGTTCATGCCAAGGGCTCAGGTGCCCATGGTATCTGGGAGTGTACTGACGGCCTAGAGGACC
TCTGCCTCGCGAACATGTTCCAAAAGGGCGCTACTTGTCCTTTGACTATCCGATTTTCAACTGTCGGGGG
AGAGTCAGGATCCCCTGACCTTGCTCGGTGAGTAGTCTAATCTTTCTTCTCAGAATGCTTGAACTGACGT
TCAAACGTAGTGATCCTCGTGGTTTTGCTGTCAAATTTAGAACGGCTGAGGGTAACTGGGACTTTGTTGC
GAATAACACTCCCGTTTTCTTTCGTGGGTTACACCCTTATACTTAGGAAACAGTTGCTGACATATTTTAG
TGCGCGATCCAGCCAAGTTCCCCCACTTCATTCACACTCAGAAACGGGACCCAACCACCCATCTTAGTGG
CGGAGATGATTCCACCATGTTCTGGGACTACCTTTCTCAAAATCCTGAATCCATTCACCAGATCATGGTA
CGTTATTATATTGTACACTAAACCAACTCGACAAATGCTGACAGCCTTGGGTACACAGATACTCATGTCT
GACCGAGGCATTCCCGCGGGATGGCGTCACATGCATGGTTATTACGGACACACCCTCAAGGTCGTTAATG
ACAACGGCGGCTGGGTTTATGCCCAATTCCACCTCATCTCTGACCAGGGCAACAAGTTCTTTACGAGCGA
AGAGGCATCTACCAAATCGCCTGACTGGGGTCAGAAGGATTTGTACGAAGCTATTGAGCGTGGAGAGTAC
GTTTTGACTTTATTCCTGATAGATTCCTCTTCAAAAATTGTTTACTGACTTATTTTCTTAGGTATCCATC
TTGGACGATGAAGGTCCAAGTTATGACACAAGAACAAGCAGAGGATGCGTGGGAAAAGAAGCGGATCAAT
GTCTTTGACTTGACCCACGTCTGGCCTCATGGAGACTATCCACTCAGGACTGTAGGCAAGATCACCTTGA
ATGAGAACCCCAGTGTAGGTCAGCTTTAATGCAATATTATGGTATCATATCTGAGTTGATCTTCTGTAGA
ATTACTTTGCTGAGATTGAGCAAGCGACGTTCAACCCTGCTCACATGATCCCAGGCGTAGAACCCTCTGC
CGACCCTGTACTCCAAGCCCGACTGTTCTCTTACCCTGACGCGCACCGCCACCGTGTTGGTCCCAACTAC
CAACAGCTTCCAGTCAACCAATCGGCCACCCCTTACGCAACGGGAAACTTTCAACGTGATGGTGCCATGG
CTTTCTACAATCAGGGAGGAAGACCCGCTTATCTCTCCAGTATCGAGCCCATCAAGTTCCAAGAGAAGCG
CGTCAACCTTAACAAAGTGCACGGTCAATTTATCGGTGAAGCTGTCAGCTTCCTCAGCGAGATCCGTCCT
GAGGACTTTAACGCCCCTCGCGCCCTTTGGCAGAAAGTGTTTAGCGACGAGTCAAAGGAACGTTTCATTC
AGACTGTTGCCGGGCACATGTCGACCTGCAAGCGCAAGGAGATTATTGCCCGTCAAATTGCCATTTTCCG
ACAAGTATCGCCTGATCTTGGAGCTCGTCTCGAGAAGGCCACTGGCGTCAGGGGCTATGGGAGTATTGAG
GGGATGTCTTTCAACGGTACTCATAATGGCTTTGGCGTTAAGCGTGGGGCGAACGGCCTTCGACAAGATG
CGGAGGTTGTGTTCAATAATGGTGCTCCTCAGAAGACTCAGAGGGCTCGTTGACTCGTAATCTGCTTCTT
AGTCGTGGCTGTTTCTAGTGCGGTCGAATTAGGTTTGTTTAGGCGGTTTTCTGGTCAACAAATAGTCGTG
TAGATATGCATGGAAATATATGCTAC
Protein Sequence 
>gi|799324461|ref|XP_012048657.1| catalase [Cryptococcus neoformans var. grubii H99]
MSARNLASGTPYGKNLPTANGTHFEAPSISSTSDSVNSAYSVGYTPVPTAERSYSGLLHGTLSKVFRKGG
QEIVVSEEPVSFNSSKADTESTRFNGCPYMNGSIPQTPTPKSTPKSASVAAPVPLPPPSAARLKAQKQNN
SIPRDNSNTLADDVGKLTVRSYEKDRDLRSQEVIYTTSNGVPVPHPYVVQRAGVNGPLLLQDFHLIDLLS
HFDRERIPERVVHAKGSGAHGIWECTDGLEDLCLANMFQKGATCPLTIRFSTVGGESGSPDLARDPRGFA
VKFRTAEGNWDFVANNTPVFFLRDPAKFPHFIHTQKRDPTTHLSGGDDSTMFWDYLSQNPESIHQIMILM
SDRGIPAGWRHMHGYYGHTLKVVNDNGGWVYAQFHLISDQGNKFFTSEEASTKSPDWGQKDLYEAIERGE
YPSWTMKVQVMTQEQAEDAWEKKRINVFDLTHVWPHGDYPLRTVGKITLNENPSNYFAEIEQATFNPAHM
IPGVEPSADPVLQARLFSYPDAHRHRVGPNYQQLPVNQSATPYATGNFQRDGAMAFYNQGGRPAYLSSIE
PIKFQEKRVNLNKVHGQFIGEAVSFLSEIRPEDFNAPRALWQKVFSDESKERFIQTVAGHMSTCKRKEII
ARQIAIFRQVSPDLGARLEKATGVRGYGSIEGMSFNGTHNGFGVKRGANGLRQDAEVVFNNGAPQKTQRA
R
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CAT1 encode putative spore-specific catalases, however cat1 mutant is absent of phenotype of virulence changes in mouse infection models (Giles et al., 2006).
References
Giles et al., 2006: Giles SS, Stajich JE, Nichols C, Gerrald QD, Alspaugh JA, Dietrich F, Perfect JR. The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. Eukaryotic cell. 2006; 5(9); 1447-1459. [PubMed: 16963629 ].