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PkNBPXb

Victor ID 5228
Gene Name PkNBPXb
NCBI Protein GI 213950526
Protein Accession ACJ54536
Other Database IDs CDD:240419
Taxonomy ID 5850
Gene Strand (Orientation) ?
Protein Name normocyte binding protein Xb
Protein Length 2845
Protein Note reticulocyte binding protein 2-like protein; Provisional
Protein Sequence 
>gi|213950526|gb|ACJ54536.1| normocyte binding protein Xb [Plasmodium knowlesi]
MGRNPFFLFFCHLLFIHSGSCKDNNRSQHHRPKRDLRLSPIHVTSLRSDQLEQIREAREHEQNNNNSDNS
NDYLNVDSKNNQKKLNSDEHNNNNSDNSNDYPNENSKNNQKKLNYDEENNSSFISLKKYKIARKPSRYSY
LDQDKKIYTVNTEDKEKKYIQKKINTPSNTFIQKAKGRSHGIVTQVNNLDYVCVMNNDDNIISLFRPYNP
EIYSFREMKHYAERNELLNKKVLTIHNDEIKRIEDILSRSMKECSNQTSELSVLINHLENPERYEIPESE
YGAKKQNYKDKLSILHECMKRNYNKHKEEIKKSHSRIYGTIDHMDCSWTNYCPTGTYYNMIALRRMDVTN
YNIRDITSFLKKIKEIYIFGQDIMKEIKGHLHTSLALETAQFILEEINYIINDMEIHLRKINKAIKDIYE
LSRQDPWSSFHRTVLQNSLFSLALRYSTFKVSVDVLNKLENASNIKIEKLHQTFRKFKDGLNNTISTHIS
STYVISTINYILSSPDEISKSLESLHTFSSEEIKEHILYSNPEIKEAKKNLDEKFAKLNEYFKNTRELAK
RINGKFVLNLKTREQLENKRNIKNKENMTPLENCKMLLSVIKDIKLDEKKLKENNKEIEQFSNRIKGIKS
NFEETSIGVHEDVRIIKELIEMEKGRHYIKEDIKKHLKYFSMVLDNIKEIISYKDKIEKYIQSMDTLIKE
YPDIEQKFTIEKIDLQNKTESIINSFYKGKIYQTFVDELAESNRKFQALEKDQHTAKGIRELYEQTKKKH
EELVNRKCDHIPQILNDLNEVINSLLQLKDKIIKEHTQKIKNDMLSVFNNLTEENKQLKKNLENYKQNAE
KMNTYYINTIKERKNKFFTTLIEKEENIPEGKDIYEEYIQHKNDVVNKESTLITHDIGVFRVNITKAKDQ
IESYKNAMQKLDTENNGTFQEIETWLESLNTKIEQLHLEDLEQELRHYKESVNNAIDEIENMKKEIDTLK
FLNILINNSNKNAKSILKIKENKNNLIKKIDIHNEELSNYRIIEEKEKSSLVDMLKELKSSVEKEIPEAS
IEELEAQEKDLKNSCENEKRHMNGIAVDSTDMDSTDTHRTNVNDSPVDRRLGTNKEKLEKYKTLCQNTEL
VINKFNANYQALEKKIDALVKNQHSQIITLIDKLIEKKRTEIKEKIELNLNSLNNTKTKINAFHFDEAVR
KDRNVTVQSKISAFETHVKDTVQNIDNEIKKMNTMKEKCDSYMEMFHKEKEEQSTEFKDRSKRMEEIYKN
MEEIYKNMEEIYNKMQEGSNILNQGTEESSVNLLDKETEESLRNILNHVKQIEMEHTRIFIHHFFHIIQE
ENEKAKLIMADIESSKKKIDEIQKGTEDVYQQKNMNNFSYEEYYTKATQSIHQINEFSNKATEDKEQADR
CNDINEIEHIKTSINSNLQKVKAEYNSIGEIREQMNSMRDLLLLNNSKAIATEIENSTEHALKFREEAVK
EHKKAKELLDQVTAKIDKAKEYKDKMNITLDDEQINDHVKNIETIKREIVNKNKNELESYVDKIKEYKDK
CKTQVINSNRGKEKIALLKTDKDNKDNNSNNVDMNKVDENIRKSEQYFKEVENLEKEAKNYVQLFMKHEQ
MINNTFEEAEILGIETKSQKKFNKGKEIIDEIKKRYSEMQEKVTDLQGKLNKLKKKPNIDNNNHDNDDDD
DVVIVEEDKVLKEELYNNEMATKAKVLIQTNLESVKYNLSQIVHIKEKGDTVYQKAIDTMNSLTEPLQNK
NTKTLDMVKIDESKYMEYVTQINECKNVIIAEMNKLNEISSNVISIEKELNASRRNYEIGLLQRMDEVSQ
SKKANMDLKKESINSTMNYFSSLSHGLELKEYDFNKNIHVHQQKMKEIYDKFEESLKKIHENLNKALLEE
NAHYTFANQLRKESQQEKAKLIHSEKEAIKYIEDMKITESMRFIHHIKENLKKISTSINEEKLRIYKGHE
FIKQIVEGIKNTDEERDISEKIQQAEEKNAQLQTHMHSTYKNTAKEMLEYITTSARFINIKIIPELTSIE
LHGNETVKLTFQSDNKDILEIENISKNENELHVQKSIEEAFHLALDINKCANDIEAQQRLNKQFISTINE
VHHKTKSIDELKNNVKIAKSKESTISNKLMDISNKIAELDQLSCEEKSYDKRFIENIEKINVKKIRDSFK
EEKGKANMDFQLNNIIKKDFVTLQTSLRSVEQAVEALKAKEIHTTYLHATKGDMERVHNKMNNIEQNIAT
LNESLDKLISKGKECEIANYTSFKSSVQSKINADEEIIHNMQKDVNQYLTFIKNNYNTIMKDIVTLNEHF
SNKVIPDYDSTNFEKANKISEELFATVEQSKSIMNNIKNAFIVVKEGTELFTTLNNSAQEIEKLYNTLDN
KKNEMNEIYKTSIFIKSQEMKSSASKYTDIGKIFNKVLETQKSEIQNNKSSVDLLKDIINIKLKNLEDTD
STFTLVSINKFDELSNNIKASIEELKQLEQTNRQKHNHVEEDKEHIAHLIKRKESLKNSLKEYEEEENFK
KLKGNIPNQVIKDIENMKEEIRKSDELYIELMKKVNENNELCKNNYTENYVSQVLEKIGELKKRFSQNLP
EKEKFLQIQGKFNEIKLLFGEIETSYNVEEFVTKMYNQMNNEKESLGDEENREKIPLAIQNVPNSKDDVK
TYLSKFTNALERINIIKKGIDDLFSSLRNNNTKAKENAKQYVNDSVKIVNELNSHISKITELKNYAENMI
NKLEEVLSKLIHSPAKDATYETQMLADETEHTHHDHSYSGDHSKGKGAHGRTRFAGSIIIGLSVISGVVL
LNRNHNSDEEEEHCEHDDHEAFEGNKDYIVHDKEEVIEVCFSDND
Molecule Role Virulence factor
Molecule Role Annotation Our study strongly suggests that P. knowlesi invasion gene variants contribute to parasite virulence. We focused on two invasion genes, and we anticipate that additional virulent loci will be identified in pathogen genome-wide studies. (Ahmed et al., 2014)
References