Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

ORC1

Victor ID 5223
Gene Name ORC1
NCBI Protein GI 70834184
Other Database IDs CDD:224391
CDD:267297
Taxonomy ID 999953
Gene Strand (Orientation) ?
Protein Name origin recognition complex subunit 1 (ORC1), putative
Protein Length 436
Protein Note single VAT derivative of TREU (Trypanosomiasis Research Edinburgh University) 927/4 (GPAL/KE/70/EATRO 1534)
Protein Sequence 
>gi|70834184|gb|EAN79686.1| origin recognition complex subunit 1 (ORC1), putative [Trypanosoma brucei brucei strain 927/4 GUTat10.1]
MKRRRDSNGKSIAALRAGVAALSVSSNIASRELTCRDSHVKAILDFLNDKVHPVMQVFGMPGTGKTASVN
HALALLASSSPAGSKPTAVFLNGYIIQKTSDIYWTLNSHLSKTRLKHAENCLPEQCPALIEKRFKQGWGS
STTPLCVIVVDEVDKVLKKHNKAFFRIVDWLSLPYAFCKLITISNSMELAADAKTRSRLDITKRLVFEPY
SLPELKEIILRRVSHIKPTLFAEKAINYLCNQTASHYGDVRRLLQSASSAICGLMMRIEEGYKLPEKHDG
LLTVKDVHSVVRQIFHDRFVEFIQTIRLPVVFISVAVIAVETARLFRANCEDSRLPIDSLFTATKRAQER
FGSVFADLHAVTLNYGAYLEIVEMLREVALIDVSVGEERIPVKTVQSLLEATERAHASMLQPFQTVVDAC
KLHDDFGTGICPLFSI
Molecule Role Virulence factor
Molecule Role Annotation Depletion of TbOrc1 resulted in derepression of telomere-linked silent VSGs in both BF and PF, and increased VSG switching particularly through the in situ transcriptional switching mechanism. (Benmerzouga et al., 2013)
References