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trans-sialidase

Victor ID 5221
Gene Name trans-sialidase
Sequence Strain (Species/Organism) Trypanosoma cruzi strain CL Brener
NCBI Gene ID 3537653
NCBI Protein GI 71410253
Genbank Accession AAHK01001396
Protein Accession XP_807431
Taxonomy ID 353153
Gene Starting Position 35836
Gene Ending Position 38658
Gene Strand (Orientation) -
Protein pI 6.46
Protein Weight 91068.77
Protein Length 940
DNA Sequence 
>gi|164450834:35836-38658 Trypanosoma cruzi strain CL Brener 1047053516005 genomic scaffold, whole genome shotgun sequence
ATCAGAAAAAAACTGCCGTAAAGAACACGTGCAGCAGCAAAGCACACGCACACAGAAGAAGCCCTCCGCC
CGAAAAGGCCGAAAGTGCAGCGCCATCGGGCAAAATCAAAACCGTACCATTGGCACCGTTGCCAGCGGGA
GTTGAGGGCGTACTGTGAGCACTGCTGTCAGCGGGAGTTGAGGGCGTACTGTGGGCACTGCTGTCAACGG
GAGTCGAGGGCGTACCGTGGGCACTGCTGTCAACGGGAGTCGAGGGCTTACCGTGGGCACTGCTGTCAAC
GGGAGTCGAGGGTGTACCGTGGGCACTGCTGTCAACGGGAGTCGAGGGTGTACCGTGGGCACTGCTGTCA
ACGGGAGTCGAGGGCGTACCGTGGGCACTGCTGTCAACGGGAGTCGAGGGTGTACCGTGGGCACTGCTGT
CAACGGGAGTCGAGGGCGTACCGTGGGCACTGCTGTCAACGGGAGTCGAGGGTGTACTGTGGGCACTGCT
GTCAACGGGAGTTGAGGGCGTAGCGTGGGCACTGCTGTCAACGGTAGTTGAGGGCGTACCGTGGGCACTG
CTGTCAACGGGAGTTGAGGGCGTACCGTGGGCACTGCTGTCAACGGTAGTTGAGGGCGTACCGTGGGCAC
TGCTGTCAACGGGAGTCGAGGGCGTACCGTGGGCACTGCTGTCAACGGGAGTCGAGGGTGTACTGTGGGC
ACTGCTGTCAACGGGAGTTGAGGGCGTAGCGTGGGCACTGCTGTCAACGGGAGTCGAGGGTGTACCGTGG
GCACTGCTGTCAACGGGAATCGAGGGCGTACCGTGGGCACTGCTGTCGCTGCTGCTGTCCATGTGTGCTT
CCGTGCCAATCAGGTCCTGGCTCAAGAACAAGGTCCTGATCTCCTCGGCATTCAGCTGACGGTTGTAAAG
AAGAACATTATTCACCGTCACGTGGCTTATGGTTGGCATATCACTCCTTTTATACCCGCCAACGTAGAAG
TGGGAGATGTCAGGCGTCCTCCCGTCTGGCACAACGGTCTGCCCTGAACCCTCCAGAGGTTCTCCATCAA
TGTACACGGAGCCAATTTTATTCGACATCGTAAGAACCACGTGGTACCTCTTACCCGTCTCCCACGATCC
CGTCGGCGTCACCGGCGTTGATCCGTATATTGGCTGCCACTGGTGCTTCTCGTCGTACGAGAGCCCCAGG
AGTTTTTTGCCACCAGAAGAGTCCAGGCTCGCACCCAGCAGAGGAGTCGCGTCCCTCGGAGCCTCGTGAA
TCGTCACCGACGCCACCAGCGTGAACGCGTGGTTTGCAAAACGATACCGTTGATTCTGCCCCTGCTGGCT
CACCGGCCAAAGCGCCCCTCCGCCAACCCCCGCAAACTTCAAACCGTTCGGAACCCTCTCCGCATTTGCC
GTGCTCGCGTTGACGCAGCGGTACGCATCCTCCCATACGTTTTGGGAGGCATTGCCGGACAAAAAGCCAA
CAAGACCAACCGTGGTGACAGCGGGACCACAACCACGCTCTGACGACGAAGCGGCTGGATCAGCAGGGGT
GCAAATGCTGGACAGGTGGCTGTCCCAATTCTTCCAGGACTGCAGCACTGATTTAATGATCCGTAGCTCG
CCAACCAGGCGTGCAAAAACAAGGCTGTACACCTCGTTAGTGTTGATCTCATGCAAACAGTACAGCTTAT
CATCCTTGTACAGGACGGAGCTGTAGGCGGAATTTTCATCACCAATGGATACTTGCCCAACGTTATAAAT
GCGCTGGTTATCCGTCAGCCAGAGGTTCAGTCGGTCGCGCAGCCACCTTCCCTTAAAATTCAGCGGGTGT
GTGAAGAGCATCACACGCATTCCTTCGATGGTCACGGCAGTGAAGCTGCTCTGACTGCCGGGCTGGTCCG
ATTTTGGTGAGGGGCCCCACACACGCGAGAGCGTGCCGACAGCCTCCACCCACGTATTCCCCATGTCACT
GGACTCGTACACCAGACGGCGTGTCCAGTCAACTCGGGTGTTTATGATGAGCTTCCCCTCCCACTCAAGG
GCCACAGGTTCAGAGCAGCCAAAATCACTCCTGCCCTTCCCAAACTTCCACGTCTTGCCCTCGTCTTCCG
AGTAGAAGATCTTGGAAAAAACTTGCTTCTTTTTGTTCGTAACCTGCACAGGGTACACAAGATTCCCGTT
GGACGCCACAATGGCAACACCCGCACCGCCAAGAAATTGATTTGTGTGCATTCCTTCCATTTCTGCCGGA
AAAAACTTCTTCAGTGACACGGGGCTCCCCCATTTGATACTCGCAGTTGTCTTGCCGCCCGCAGTGGACT
TCGTGACCTCACCAACGGCAAGCAGAATATCCCAGTCTCTCGCATCACCATGCGACGTCCAGTAGCTTCT
CGAACTATTGTAGCTTCCAACCAGGACGTAAAGCTTGTTGCCCTTCACAATCACTGTGGGATCCACCACA
CGAGAAACAGACGATGCACGACTGTTCTTGATGGCAATTTGGGTCTCCCACGTCTCCCCATCGTCCACGC
TGTACTTCGCCACCGTATCAATGAGGGAGTTGTCATTGGATGTTTCGTAGCGAGCGTCCGCGATGGCAAC
CATCACCCCGTCCACATTAACAAGGGCGGGGAGGCGGAACGAGTGGACAACCCGCTCGGTGACTTTGCCG
TCCTTTTCAAATGGCACCTTCGAGCTTTGCCGCTTAAACAGCTCAACTCGGCTCGATTCGGGTGCCAGGG
CATGCGCGGGCTCGCTGGGGCAGAGCGCAAGAAGAAGCGGCACGAAAAACATTAGCCAGAACATCCTACT
GGCCCCAACGACTGTTTTCCCCA
Protein Sequence 
>gi|71410253|ref|XP_807431.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
MGKTVVGASRMFWLMFFVPLLLALCPSEPAHALAPESSRVELFKRQSSKVPFEKDGKVTERVVHSFRLPA
LVNVDGVMVAIADARYETSNDNSLIDTVAKYSVDDGETWETQIAIKNSRASSVSRVVDPTVIVKGNKLYV
LVGSYNSSRSYWTSHGDARDWDILLAVGEVTKSTAGGKTTASIKWGSPVSLKKFFPAEMEGMHTNQFLGG
AGVAIVASNGNLVYPVQVTNKKKQVFSKIFYSEDEGKTWKFGKGRSDFGCSEPVALEWEGKLIINTRVDW
TRRLVYESSDMGNTWVEAVGTLSRVWGPSPKSDQPGSQSSFTAVTIEGMRVMLFTHPLNFKGRWLRDRLN
LWLTDNQRIYNVGQVSIGDENSAYSSVLYKDDKLYCLHEINTNEVYSLVFARLVGELRIIKSVLQSWKNW
DSHLSSICTPADPAASSSERGCGPAVTTVGLVGFLSGNASQNVWEDAYRCVNASTANAERVPNGLKFAGV
GGGALWPVSQQGQNQRYRFANHAFTLVASVTIHEAPRDATPLLGASLDSSGGKKLLGLSYDEKHQWQPIY
GSTPVTPTGSWETGKRYHVVLTMSNKIGSVYIDGEPLEGSGQTVVPDGRTPDISHFYVGGYKRSDMPTIS
HVTVNNVLLYNRQLNAEEIRTLFLSQDLIGTEAHMDSSSDSSAHGTPSIPVDSSAHGTPSTPVDSSAHAT
PSTPVDSSAHSTPSTPVDSSAHGTPSTPVDSSAHGTPSTTVDSSAHGTPSTPVDSSAHGTPSTTVDSSAH
ATPSTPVDSSAHSTPSTPVDSSAHGTPSTPVDSSAHGTPSTPVDSSAHGTPSTPVDSSAHGTPSTPVDSS
AHGTPSTPVDSSAHGKPSTPVDSSAHGTPSTPVDSSAHSTPSTPADSSAHSTPSTPAGNGANGTVLILPD
GAALSAFSGGGLLLCACALLLHVFFTAVFF
Molecule Role Virulence factor
Molecule Role Annotation The trans-sialidase (TS) is a virulence factor involved in cell invasion and pathogenesis that is differentially expressed in aggressive and less virulent parasite stocks.
(Burgos et al., 2013)
References