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LmexCht1

Victor ID 5217
Gene Name LmexCht1
Sequence Strain (Species/Organism) Leishmania mexicana MHOM/GT/2001/U1103
NCBI Gene ID 13450317
NCBI Protein GI 401418548
Locus Tag LMXM_16_0790
Genbank Accession FR799569
Protein Accession XP_003873765
Taxonomy ID 929439
Chromosome No 16
Gene Starting Position 290300
Gene Ending Position 291673
Gene Strand (Orientation) -
Protein pI 6.83
Protein Weight 47780.29
Protein Length 457
DNA Sequence 
>gi|401418731:290300-291673 Leishmania mexicana MHOM/GT/2001/U1103 complete genome, chromosome 16
TTCATAGATCGCGGTCCTCAGCCACGTCGGGAGATGAATCCTGCGGCAGTGGTTGCGGACAATCGTATGC
ATTACCGCTATTCACGTTGCCACCACTACCATGTCTGCTGTCAGTCAGCAACCCCCAGTCGGCCAGCTGC
TCGTGAACGGCAGTCATGAGCGACATGGGCGAAGTCCCCGGTGGCACATCCTGGCCCAGCTCCCAGATCA
TTATCCCAGACAAGTTAGCAGCGCGTGCCAGTCGCATCTTGCGCTTCACATCGTCGTAGCCGGTGAAGCT
GTACCCGCCATACTCGCTCAATGCCCGCAGCTCCGCACCTCCCTCGACCCATGTCGGGTGGTTCTTGCTA
GCCCATTCTTGGATGAAGAGCCAGAGCCGGTCGTACGCCTCAGGCTGTAGTCGCCTGTCCTCCCGATGAC
GGCCATAGAAGGGGATCCCAAGGGTGAGCTTGCGGCGGTGGTCCTGAATGATGCGCGGCCGCTGGTGCAT
CTGCCCAAGACGCCTGTTGTATATACCCTCGTTAAAGAGACCGATCGTCCCCTCACTGAGCACTGAGGCG
GCGTACTCGACGGAGCTGTGTGGCCCGGTCCCGACAGCGTGGTCGTACGCCATCAAGTGCACATAGTCGA
GCGAGTGGAGCACGCGAGCGGACTGCAGTACGGCTGCCATAGATGGGTGGGGATGGAGGGCCATGGACAA
GACAGCGCGCCGCACTCGGAGGCGGTGGCGCCGCTCACCAGCCGGTTTACCTGCGTGTTCGTCGCCTGCA
GCAGCCGCATAGCCCAGGGAAGACCGGAGCTCCATCAGGAAGCGGCCAAAGTTCAACCACTCTGTCATCG
TCTGCGGGTACTCCCAGTTGAAGTCGATGCCGTCGAGCTTTCGTGCCAGCAGCACCGCGTTCACCTCCTC
TATGAACGCTCGCCGCCGCACCGTGTCCCCAACGAGGTCCGCAAACCCCGCGCTGCGGCCACCACCACCG
ATGCAGAGCATCAGCTGTGCACCGTGCAGGTCTGCCAGCCGGCGGATCCGGGCCCACTCGTCGCCCGATG
GCAGCCGGTCATCCACATGGATGAGACGCAGCGTTGCGGGGTCCACCTCGGCACTGAAGAAGATAAGATG
CGTCAACCCTGCGTTGAAGAAGGCCTCGTAGTGGAACGAGTCCTGACGGTACTCGGGCAAGTACCCGAAG
ACAGTAAAGAGCGGGGGAGGAGAAGCCGCAGTTATCGAGGTGTTGTGCCCGCTACCGATGGCGGTATCGC
CCGCAGCTGCAGGAGCAGCAGCGGCTATAGCCGAGCTCACTGGAGTGCTCACACAGCTGGAGTAAAGCGC
TGCTACAAGACACGCCAGCTGCACAAGTGAGCTCCTCTGCACCA
Protein Sequence 
>gi|401418548|ref|XP_003873765.1| chitinase [Leishmania mexicana MHOM/GT/2001/U1103]
MVQRSSLVQLACLVAALYSSCVSTPVSSAIAAAAPAAAGDTAIGSGHNTSITAASPPPLFTVFGYLPEYR
QDSFHYEAFFNAGLTHLIFFSAEVDPATLRLIHVDDRLPSGDEWARIRRLADLHGAQLMLCIGGGGRSAG
FADLVGDTVRRRAFIEEVNAVLLARKLDGIDFNWEYPQTMTEWLNFGRFLMELRSSLGYAAAAGDEHAGK
PAGERRHRLRVRRAVLSMALHPHPSMAAVLQSARVLHSLDYVHLMAYDHAVGTGPHSSVEYAASVLSEGT
IGLFNEGIYNRRLGQMHQRPRIIQDHRRKLTLGIPFYGRHREDRRLQPEAYDRLWLFIQEWASKNHPTWV
EGGAELRALSEYGGYSFTGYDDVKRKMRLARAANLSGIMIWELGQDVPPGTSPMSLMTAVHEQLADWGLL
TDSRHGSGGNVNSGNAYDCPQPLPQDSSPDVAEDRDL
Molecule Role Virulence factor
Molecule Role Annotation the LmexCht1 transfectants survived significantly better in human macrophages and also produced significantly larger lesions in mice than control parasites.
(Joshi et al., 2005)
References