Victors

GRA2
Victor ID	5214
Gene Name	GRA2
NCBI Protein GI	2506908
Taxonomy ID	5811
Gene Strand (Orientation)	?
Protein Name	Dense granule protein 2
Protein Length	185
Protein Note	Protein GRA 2; 28 kDa antigen; GP28.5
Protein Sequence	>gi\|2506908\|sp\|P13404.2\|GRA2_TOXGO RecName: Full=Dense granule protein 2; Short=Protein GRA 2; AltName: Full=28 kDa antigen; AltName: Full=GP28.5; Flags: Precursor MFAVKHCLLVVAVGALVNVSVRAAEFSGVVNQGPVDVPFSGKPLDERAVGGKGEHTPPLPDERQQEPEEP VSQRASRVAEQLFRKFLKFAENVGHHSEKAFKKAKVVAEKGFTAAKTHTVRGFKVAKEAAGRGMVTVGKK LANVESDRSTTTTQAPDSPNGLAETEVPVEPQQRAAHVPVPDFSQ
Molecule Role	Virulence factor
Molecule Role Annotation	The survival rate of mice inoculated with Deltagra2 was significantly higher; some infected mice survived the acute infection, whereas all mice infected with the wild-type strain RH succumbed to early death. absence of GRA2 partially attenuates the virulence of T. gondii during the acute phase of infection and allows for establishment of chronic infection by the otherwise highly virulent RH strain.(Mercier et al., 1998)
References


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