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GRA6

Victor ID 5212
Gene Name GRA6
NCBI Protein GI 37538307
Other Database IDs CDD:113839
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name Dense granule protein 6
Protein Length 230
Protein Note Protein GRA 6; Antigen p32; Protein p33
Protein Sequence 
>gi|37538307|sp|Q27003.2|GRA6_TOXGO RecName: Full=Dense granule protein 6; Short=Protein GRA 6; AltName: Full=Antigen p32; AltName: Full=Protein p33
MAHGGIHLRQKRNFCPVTVSTVAVVFVVFMGVLVNSLGGVAVAADSGGVKQTPSETGSSGGQQEAVGTTE
DYVNSSAMGGGQGDSLAEDDTTSEAAEGDVDPFPVLANEGKSEARGPSLEERIEEQGTRRRYSSVQEPQA
KVPSKRTQKRHRLIGAVVLAVSVAMLTAFFLRRTGRRSPQEPSGDGGGNDAGNNAGNGGNEGRGYGGRGE
GGAEDDRRPLHPERVNVFDY
Molecule Role Virulence factor
Molecule Role Annotation the dense granule proteins GRA4 and GRA6 in cyst development since brain tissue cyst burdens were drastically reduced specifically in mutant strains with GRA4 and/or GRA6 deleted. Complementation of the Ãˇâ€¯gra4 and Ãˇâ€¯gra6 mutant strains using a functional allele of the deleted GRA coding region placed under the control of the endogenous UPRT locus was found to significantly restore brain cyst burdens.(Fox et al., 2011)
References