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PLA2

Victor ID 5209
Gene Name PLA2
Sequence Strain (Species/Organism) Leishmania major strain Friedlin
NCBI Gene ID 3684469
NCBI Protein GI 72548599
Locus Tag LmjF35.3020
Genbank Accession CP000081
Protein Accession XP_843407
Taxonomy ID 347515
Chromosome No 35
Gene Starting Position 1234330
Gene Ending Position 1235691
Gene Strand (Orientation) -
Protein pI 8.39
Protein Weight 46546.27
Protein Length 453
DNA Sequence 
>gi|72550132:1234330-1235691 Leishmania major strain Friedlin chromosome 35, complete sequence
TTTACCCCCTCAGCGCAGCGGCGAGCGCCGAGTCGTTGAGAAGTTTGGTGTCGAGGGGCAACGGGCCGGA
GACCTTTTCAATGAACCGCATTGTTTCTGCTGCGAACGCTACAATGCAGCCTCGCGGTGACGCCGTCATG
TAAGCCGCGCGGTACAATACCGGACTGAACAATGAGACGTCCGTGCACGTCAAGTGTCCAGTGCCGCGGT
AGTCCTTTATCGTGTACCACGACGTCTTCATCACCTTCAGCTTGGCGTCGACTGCTGACACAAGAGCGCT
CTCCTCAGTCGTGCGCGGCTGTGCGTCGACGATGGCCTTGACCTCCTCAAAGAACGCGTGCTGTTCCTTG
CTCCGCACCCACTCCTCAGAGAAGATCTGCAGCGTTGGTGTGGTGAAGTGGACCGGTTGCTTCCTGTCCG
TGAGCTTGTCGTAGAACATCGTCTTCTGTAGTGGGATCATCCAAGGGTCATAGACGACAGTGCTGGCGAT
GCTGCTCACCCCGCCCCTTTCACTCGCGGCTTGCGTGTCAGCCAGGGCAGCCGCCAGGCATGTCGCGCCG
CCAAACGAATGCCCAAGAAGGTGAATGCGCGGCTCCTTTTCGATGTACTTGTCCACCGTCTCCTTGTCGT
ACCCGAGCGCGAGCAGTAGCTCGCCGCTGCGGATGCGCTTGATTGTGTTGAGGGTCTCTCGGATGCGAAC
CTCTAGCTGCGGAGCGCGATCCTCGGAAGTCCAGCCTACCTGGGTGTTCAGCGGAATGCGAATCTCCCTC
TCGGCGTCGCGGCAGAAGGCAGCGCTGCCGTCCATGTGCGACAGGGCAAACACGACGGCCCCGCGCACAG
CGAGGTCCATCAGCAGTGTGCTGTACAAGTGCGGAAATCCGCCAAGACCGTGGCTGAACACGATCATCGG
ACGTGGCATGCCATCGCGCTGGAAGAGCGGCGCTGGCTCCGCGTTAGGTCGCATCTTCTTGCGCAGAAGC
CAAAGGTCCTTCACCAGTGCGTAGGGGACTTTACTGTAACTAGCTATGCCAACCAGGTAACTGCGCTCGC
CAAACGGAATGTACTGAATTCCGCTCCGCGGCGTGCCGCTAGCGGTCGGGTAGACGATGGTGACGGGGGG
CTTCATGGCACCGCGCTCACCACACACCTCACGCGTGCCCACGTTGAAGCTTCCCCCAAGCGGGGAAAAG
CACTGCAAGGGCTGAACGTAGAAGACGGCGCAAGTCACAAGTGAACCCACACAGGTCATCATGATGCACA
CCTTCCAATCCACCCCCCACGCCGCCGCAAGGCATGACAGCAGCACCGACGCCCCGGCCGGCAGGTAGTG
AATAGACAAGATGTAGTCGAAGATTGGGTGCA
Protein Sequence 
>gi|72548599|ref|XP_843407.1| phospholipase A2-like protein [Leishmania major strain Friedlin]
MHPIFDYILSIHYLPAGASVLLSCLAAAWGVDWKVCIMMTCVGSLVTCAVFYVQPLQCFSPLGGSFNVGT
REVCGERGAMKPPVTIVYPTASGTPRSGIQYIPFGERSYLVGIASYSKVPYALVKDLWLLRKKMRPNAEP
APLFQRDGMPRPMIVFSHGLGGFPHLYSTLLMDLAVRGAVVFALSHMDGSAAFCRDAEREIRIPLNTQVG
WTSEDRAPQLEVRIRETLNTIKRIRSGELLLALGYDKETVDKYIEKEPRIHLLGHSFGGATCLAAALADT
QAASERGGVSSIASTVVYDPWMIPLQKTMFYDKLTDRKQPVHFTTPTLQIFSEEWVRSKEQHAFFEEVKA
IVDAQPRTTEESALVSAVDAKLKVMKTSWYTIKDYRGTGHLTCTDVSLFSPVLYRAAYMTASPRGCIVAF
AAETMRFIEKVSGPLPLDTKLLNDSALAAALRG
Molecule Role Virulence factor
Molecule Role Annotation Deletion of PLA2/PAF-AH in Leishmania Major is dramatically attenuated the virulence in BALB/c mice(Pawlowic and Zhang, 2012)
References