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dltA

Victor ID 520
Gene Name dltA
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 986449
NCBI Protein GI 16803014
Locus Tag lmo0974
Genbank Accession AL591977
Protein Accession NP_464499
Other Database IDs UniProtKB-ID: DLTA_LISMO
UniRef100: UniRef100_Q8Y8D4
UniRef90: UniRef90_B8DEG2
UniRef50: UniRef50_Q721J2
UniParc: UPI00000552EC
EMBL: AJ012255
EMBL: AL591977
EMBL-CDS: CAB51919.1
EMBL-CDS: CAC99052.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0974
GenoList: LMO0974
HOGENOM: HBG320748
OMA: FICTEEL
ProtClustDB: PRK04813
BioCyc: LMON169963:LMO0974-MONOMER
Taxonomy ID 169963
Gene Starting Position 1005035
Gene Ending Position 1006567
Gene Strand (Orientation) -
Protein Name D-alanine--poly(phosphoribitol) ligase subunit 1
Protein pI 4.78
Protein Weight 54586.24
Protein Length 510
Protein Note transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid
DNA Sequence 
>gi|16802048:1005035-1006567 Listeria monocytogenes EGD-e, complete genome
CTCACTTGTTAACCTCACTATTAAGTGATTTGCGATCAATTTTGCCATTCATAGTTAACGGGAAGTCCGT
TTTATAAATCCATTTTCGGGGGATCATGTATGCTGGCATAAATTCTTTTAGTTCTTTTTTTATTGCTGCA
CTTAGCTGGTATTCTTTTTCGAAATCATGGGTAGTTGGGATGACCTGAGCGACTAACATATCTACCTTTT
CATCTTTCATTTTCGGAATAATAGCGCAGTTTTGAATGTAACTTACTTTTTTTAGGTTGTTTTCGATATC
TTCTAATTCGATGCGGTAACCATGAAGTTTAATTTGGAAGTCAAGACGTCCTTGGAAGAACAGATAACCG
TCTTTGATAATACCAGAGTCTCCTGTGCGATAGGCTTGATAACCTTTATAATCGAAGAATACTTGGTCTG
TTTTTTCAGGTTCATTTAAGTAACCTTTAGAAACGCTAGCACCAATTAGGACAATTTCTCCTTTTTCGCC
TTCTGGAAGAACCTCACCAGTTTCTTGGTCAACGATGTGTAAACGCATATCTGGTTTAATAACGCCAAGT
GGTAAGCTTGGATAAGCATCGATAATCTCTCGAGTTACTTTCACTTGGGTAACAGCCACGGTTGCTTCTG
TAGGTCCGTATGTATTGTAAATAACTGCATCTGGGAAACGGTCCAGTAATTCGCTTGCTGTTTTCTTGGC
AAGTACTTCACCACAGAATAAGAAACGAGTTAAGCGGGGGTTATTTTCTTGGTTAAAGTTCTCGTCTAGT
AAGCACAAATCTGCAAAAGAAGGAGTAGAAACCCATACATCCAAGTTTTGAGCAGGTATTTCACGATATA
GATCTTTCATATTCGCAGTAATTGTTTTATCAAGAGGTACAAGCGTCCCACCCGATAGTAAACTTGGGTA
TAAATCCATAACGGATAGATCGAAGGAGAAGGGCGCTTGGTTTAAGAAACGCAATCCTTGGCTTAAAGAA
AAGTCTTGTAAAATCCAGTTACTAAAACTTACTAGGTTGTTTTGACTGATTTGAACGCCTTTAGGATTTC
CTGTACTTCCAGATGTGTAAATAATATAGTAGTTATCATCATTGTTTACACATGCTTCTTTGTCTGGAAC
TTCTCCGAAATGTTTTTCTAAAGCGTCCATTAGCTGATCTTGTGTTAGCACCGGACAACCAGTAATAGTA
AGGTTGTTAGGCAGCTCTTCTGTGCAAATAAACATAGAAGGATCAGCTGCTTTTTTTATTTGTTCTATAC
GTTCAACTGGCATAGAAACATCTACTGGTACATAAGCTCGACCTGATTTGATAGAGCCTAAGAATGCAAC
TAACATTAGGGGAGACATATGGCCGTAAACGATAATAGGTTTTTCTTTGTCAGTAATTAGGTTTTTTAGT
AGAAAAGAGCCGAATGCATCAGATTGCCGTTTTAGTTCTTTATAGGAAAGACGTGTTCCAGCATATTCAT
AGCAAGGGAAATCCGGTGTCTTCTCTGCCCATGCATCAATTCTTTCTATGATACTCGTTGTCA
Protein Sequence 
>gi|16803014|ref|NP_464499.1| D-alanine--poly(phosphoribitol) ligase subunit 1 [Listeria monocytogenes EGD-e]
MTTSIIERIDAWAEKTPDFPCYEYAGTRLSYKELKRQSDAFGSFLLKNLITDKEKPIIVYGHMSPLMLVA
FLGSIKSGRAYVPVDVSMPVERIEQIKKAADPSMFICTEELPNNLTITGCPVLTQDQLMDALEKHFGEVP
DKEACVNNDDNYYIIYTSGSTGNPKGVQISQNNLVSFSNWILQDFSLSQGLRFLNQAPFSFDLSVMDLYP
SLLSGGTLVPLDKTITANMKDLYREIPAQNLDVWVSTPSFADLCLLDENFNQENNPRLTRFLFCGEVLAK
KTASELLDRFPDAVIYNTYGPTEATVAVTQVKVTREIIDAYPSLPLGVIKPDMRLHIVDQETGEVLPEGE
KGEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYRTGDSGIIKDGYLFFQGRLDFQIKLHGYRIELEDI
ENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPTTHDFEKEYQLSAAIKKELKEFMPAYMIPRKWIYKTD
FPLTMNGKIDRKSLNSEVNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant displayed impaired adherence to various cell lines in vitro, and impaired virulence in mice (Abachin et al., 2002).
COG COG1020Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Abachin et al., 2002: Abachin E, Poyart C, Pellegrini E, Milohanic E, Fiedler F, Berche P, Trieu-Cuot P. Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes. Molecular microbiology. 2002; 43(1); 1-14. [PubMed: 11849532].