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ipaA from Shigella flexneri 5a

Victor ID 52
Gene Name ipaA from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876595
NCBI Protein GI 13449071
Locus Tag pWR501_p132
Protein Accession NP_085287.1
Other Database IDs UniProtKB-ID: IPAA_SHIFL
UniRef100: UniRef100_P18010
UniRef90: UniRef90_P18010
UniRef50: UniRef50_P18010
UniParc: UPI000012D7D0
EMBL: X17628
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL: J04117
EMBL-CDS: CAA35624.1
EMBL-CDS: CAC05800.1
EMBL-CDS: AAK18443.1
EMBL-CDS: AAL72353.1
EMBL-CDS: AAA26525.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
PDB: 2GDC
PDB: 2GWW
PDB: 2HSQ
PDB: 2IBF
MINT: MINT-6174234
EnsemblGenome: EBESCG00000093043
EnsemblGenome_TRS: EBESCT00000093999
EnsemblGenome_PRO: EB
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 100202
Gene Ending Position 102103
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|13448939:100202-102103 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TTTAATCCTTATTGATATTCTTTAATACTTTTGATAGGGAAGTGGTTACATCTTTTGCTGCTTTATATAT
ATTATTGTTTTCAGCTGTAATATCATTGTTATTTTTTAAATCAGATATATCATCTGTAAGTAATTCTGCA
GAGGTATCGTCAATTTTTGACAATACCTTGCTGAGGGCGCTAGATACTTCTTTTGCCTTTTCATAGATCG
CATGATTTTTATCAATTGTATCTGCGTTGGTTTCTGTTACGTAGTTTCTTATATTTGCATCTGTAACTTT
TAATTTGTTGTTTATTCTATGTTCTGTTGTGGATTTTGTAATGTCCTTTGATTTTTCCTGTAACTCTCGT
TCTTGTGTTCCTGATTTAGTTCCAATGAGAGATATAAGATTACTTAGGGAGTTTGTTACTTTTTTTGAAG
CTTCAAATATCGTTTCCCGTGTTAAATATGTGTCTCCATTTCTTGATAAAAAATCAGTCTGAAGTACTTT
TGAATCAGTGTTTGAGTTGAATTTATTGATTTGCGAAGCTACTCTATGAGAAAGAGAAGCGCTACTTTTA
GTTGTATCTGATGAGTTATCATTACTGCTTGTCACTCCTTCCGGGTGGAGAGGGGGGGTGGTTGAAGAGT
TCTGTATGTTCAGAGGCCTGTGTCCCCGAGAAAGAGAGTTATTTGCAGATCTTTCTTGACTACTCGTAGT
TAACAGGTCTGAACCTATTCCATCCGAATTATCTGGAGTATGGTTGAAAACCTTTTCTAAAGCTGAATTA
TTTGCAAATGTCTGGACAGTATCTGATATAGAGTGTGGTAGAACGGAAGTTACTTTTTGAACTAGTGCTC
TTTGTGGATTTAGTAATGAGTTTCCGTTACGGGATAATAGATCGTTTGTCTGAGAAGTAGGAGACTGTGC
ATCATTTTCTGGGTTCTCGTGATAGCTATTGTCATATACTCTGTTGTCAAAAACTCTATTATCGTAAGTT
CTATTATCATTATTTATATGATAGTGAATTACAGGTTGGGATGTTTTCTCATTGGCTCCGGGGGTTGGTC
CGCCATCTGGCATATCTTCGGGAGGTGTAGGGAGGCCATCTTGGATAGGATGCGAATCTTTTATATCTTC
TAAAATATCATTAAGGACTTTTCTCAACAGCTCAGGAAACACGGCTACTGTATTTAAGTCTCTTGACAGT
TTACCTATACCAAATCCTTTACTATCAATAGTATTTTTACGTTGATTGCGCAAACTATCAAAGGCAAGTT
TTGCCTGTGCGTCAACTAAATCATCTAGTTTGAGAGATGAAACAGTTTCATTACTTAACTTTAATTCAGC
AAGAATATTATTCTTGATAAATGATGATACTTCAGTATTGAGGAGTTTTTGTCCCAATGATAAAGCTTCA
CCAGATGTGTGTTGTTGTGCTAATAGTGCAAGTCTGTGCTCAATGTTTTGTCGTAATTGATGGAGTTTCT
TATTCTTTGCCGACCATGGTCCAAAGGCAGAATCTTGGGATAATTTATCTTTTATAATTAGTTCCGAATA
CTGTGCGACAATTTTTTGAAGTCCCTTTTCGTTTTCAAAATTAAGACCATTTTGATGTACTAAGGAGTAC
AAAACATTTGAAAATTCGAGAATCTCGCTTTTGGCATACGCATTCATTGAGTTGGAATAAATGCTTCTTA
ACACATCTTCTTTCCCTGAGGAAGAAAATAAAAAATCAAGACATTTCTGATTAAAAGACGTTGCAAAGTT
TTCTTTTTCAGACACTGATGCTGGTGTTTTTAGAGAAGTTTGCGAACTATGGATATCGGATATTTTGCTT
TTTAACTCGCTGTATTCTGTTGATGATGGTGAAGTTGCCTTATATAAGAATGTTGGCGCTTGAGTATTAT
TTACATTATGCA
Protein Sequence 
>gi|13449071|ref|NP_085287.1| invasion protein [Shigella flexneri 5a str. M90T] MHNVNNTQAPTFLYKATSPSSTEYSELKSKISDIHSSQTSLKTPASVSEKENFATSFNQKCLDFLFSSSGKEDVLRSIYSNSMNAYAKSEILEFSNVLYSLVHQNGLNFENEKGLQKIVAQYSELIIKDKLSQDSAFGPWSAKNKKLHQLRQNIEHRLALLAQQHTSGEALSLGQKLLNTEVSSFIKNNILAELKLSNETVSSLKLDDLVDAQAKLAFDSLRNQRKNTIDSKGFGIGKLSRDLNTVAVFPELLRKVLNDILEDIKDSHPIQDGLPTPPEDMPDGGPTPGANEKTSQPVIHYHINNDNRTYDNRVFDNRVYDNSYHENPENDAQSPTSQTNDLLSRNGNSLLNPQRALVQKVTSVLPHSISDTVQTFANNSALEKVFNHTPDNSDGIGSDLLTTSSQERSANNSLSRGHRPLNIQNSSTTPPLHPEGVTSSNDNSSDTTKSSASLSHRVASQINKFNSNTDSKVLQTDFLSRNGDTYLTRETIFEASKKVTNSLSNLISLIGTKSGTQERELQEKSKDITKSTTEHRINNKLKVTDANIRNYVTETNADTIDKNHAIYEKAKEVSSALSKVLSKIDDTSAELLTDDISDLKNNNDITAENNNIYKAAKDVTTSLSKVLKNINKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipaA mutants are attenuated in invasion of HeLa cells (Tran et al., 1997).
References
Tran et al., 1997: Tran Van Nhieu G, Ben-Ze'ev A, Sansonetti PJ. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. The EMBO journal. 1997; 16(10); 2717-2729. [PubMed: 9184218].