Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

Rop5

Victor ID 5197
Gene Name Rop5
NCBI Protein GI 134035971
Other Database IDs CDD:258671
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name rhoptry protein 5
Protein Length 549
Protein Note Kinase-like; pfam14531
Protein Sequence 
>gi|134035971|gb|ABO47818.1| rhoptry protein 5 [Toxoplasma gondii]
MATKLARLATWLVLVGCLLWRAGAVQLSPPNSRTNDLASGTPHVARGDTEAQSGTGDDSDFPQGVVEEVA
DMSGGRVPRVPASSTTTSASEGIFRRLVRRLRRGRGTADGAGVADETHQGPRPPLRKRLAQHFRRLSGFF
GRLTPRWLSGLGRRAQRWWRGRQRPLLDPSLHGLEAGDSFMRDLLKHEKELIGYCREEALKEPAAMVEAV
MATVWPQNAETTVDSLLSQGERKLKLVEPLRVGDRSVVFLVRDVERLEYFALKVFTMGAENSRSELERLH
EATFAAARLLGESPEEARDRRRLLLPSDAVAVQSQPPFAQLSPGQSDYAVANYFLLMPAASVDLELLFRT
LDFVYVFRGEEGILARHLLTAQLIRLAANLQSKGLVHGRFTPDNLFLMGYGPVMLGDASALWKVGTRGPA
SSVPVTYAPREFLNANTATFTHALNAWQLGLSIYRVWCLVLPFGLVTPGIKRTWKRPSLRVPGTDSLLFD
SCIPVPDFVQTLTRRFLNFDRRRRLLPLEAMETPEFLQLQNEISSSLSTGQPTAAPSVA
Molecule Role Virulence factor
Molecule Role Annotation it is striking that deletion of the ROP5 cluster in a highly virulent strain caused a complete loss of virulence, showing that ROP5 proteins are, in fact, indispensable for Toxoplasma to cause disease in mice.(Reese et al., 2011)
References