Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

CK1

Victor ID 5193
Gene Name CK1
Sequence Strain (Species/Organism) Leishmania donovani
NCBI Gene ID 13388740
NCBI Protein GI 398016612
Locus Tag LDBPK_251640
Genbank Accession FR799612
Protein Accession XP_003861494
Taxonomy ID 5661
Chromosome No 25
Gene Starting Position 624147
Gene Ending Position 625703
Gene Strand (Orientation) -
Protein pI 9.39
Protein Weight 55910.31
Protein Length 518
DNA Sequence 
>gi|398016801:624147-625703 Leishmania donovani BPK282A1 complete genome, chromosome 25
CCTACATGCGCAGGCGATCCGGCTGCAATGGACTGCTGAACATAGGACGCTTGCTGCCAAAGGCGCTGTT
CTTGTCGCGCTGCGTCGATCCGTTCATTACGTCGGAGACATCCTCGAGGCGCAGCTCGCTGTTGCGAGAC
GCGATAGCCGACATCTGCGTTTCGAGCCGCTGCTGCCGCGACTGCTCCTCCATCCCCCTCTTGACCTCCA
TCTGCCGCTTACAGAACCAGTCGAAGCACCAGTCATACGGGCCGCGCATCGGATCGACGTCCTCGAGAGT
CGGCAGGACCTGCGCTGCGACGGTGCTGGGGGTCTGGAACGGATGGCTGCGCCGGCTGTTCACCGTAGAC
TCACTCACGACACTCAGCAGCCGCGAATCGGTCGGGGATGTGATATCGGTGGACAACATGGCGGGCACCG
CGAGCGGGTTGGACGGTTTTGCGCCAGTGCGGTTTGCTGCGCAGAAGTTGCCACTAGGCAAATCGCGCGC
GGGCAGTGTCAGCCCGAGCCGCTTGCCTAGATCGCGGAACAGGCGCCGCAGGCTGTCGTAGTCCGGCTTC
TGTGTGAAGGACAAGGAACGACAGTACTGGCAGTAGTTGAGAAACTCCTTTGGCATCCCCTTGCACAGCT
CCTCCAGCGGCGTGGCCATCTTAGTCTCCCCGATCTTGATGGTTTTGATCTGCTGGTCCTTCGCCTGGAT
CCCTTGCCAGGGCAGGTTGCCTCGCAGAAAGTAGATGAGGAGAAAGCCGATGGACTCGAGGTCGTCACGG
CGGCTCTGCTCGAAGCCGCGGTGCACATTGGTGCTGCAGTAGCGCGCCGTCCCGGTCAGCGGGCGACCCT
CCGCAAAGGGGATGTGACTGTTTTTCTTCACCTCCCAGTACAGCTTGGAAAGCCCGTAGTCGATGATGTA
GAGGATGTGCGCCTTGGACCGGCAGCCGAACACGAAGTTTTCTGGCTTGATGTCGCGGTGCACGAAGCCT
TTTTCGTGAAAGTACTGAATTCGGTGCAGCAGCTGATCAGCAATCATGAGCACCGTCTTGAGAGAGAAGC
GACGGTGACAGTAGTTGAAGACGTCCTCCAGCGAGGGGCCGCACATCTCCATCACCATGATGTTGTAATC
GCCCTCGCTGTCGAAGTAGTAGATTTGCGGAATGCCGACAACGATGCTGATCTCTAATGATTTGCGCTGC
TGCTGCGCGGTGGCGTTGACGCTCTGTGGCAGGTTGGATGGGGTATTGTTGCTGTCGCCCTGCGCCGTGC
CACCGTTCACAACGCTGTGGTTGCTGCCCTCCGCAAAAAGTTGCTTTGGGTTCACTTCATTCTGCCCCAC
TGGGGGCTGATGCAGCACGCGGTACACCTTGCTTTCGTAGGACAGCTGCGGATAGCGCGCCTTTTTGCGC
TCCAGCTTCACCGCGACGATGCGGTGGCTCTTCTTGTCGTAGCCTTCGAAGATGTCGCCGAAGGAGCCGT
TGCCGAGGCGGTGGCTGAGAAGAAAGCGGCCTCCCCCAAACGGGACCTCCTTGCCAGTCGGCTGATACTT
CTCGGATACAGAGGCCA
Protein Sequence 
>gi|398016612|ref|XP_003861494.1| casein kinase I, putative [Leishmania donovani]
MASVSEKYQPTGKEVPFGGGRFLLSHRLGNGSFGDIFEGYDKKSHRIVAVKLERKKARYPQLSYESKVYR
VLHQPPVGQNEVNPKQLFAEGSNHSVVNGGTAQGDSNNTPSNLPQSVNATAQQQRKSLEISIVVGIPQIY
YFDSEGDYNIMVMEMCGPSLEDVFNYCHRRFSLKTVLMIADQLLHRIQYFHEKGFVHRDIKPENFVFGCR
SKAHILYIIDYGLSKLYWEVKKNSHIPFAEGRPLTGTARYCSTNVHRGFEQSRRDDLESIGFLLIYFLRG
NLPWQGIQAKDQQIKTIKIGETKMATPLEELCKGMPKEFLNYCQYCRSLSFTQKPDYDSLRRLFRDLGKR
LGLTLPARDLPSGNFCAANRTGAKPSNPLAVPAMLSTDITSPTDSRLLSVVSESTVNSRRSHPFQTPSTV
AAQVLPTLEDVDPMRGPYDWCFDWFCKRQMEVKRGMEEQSRQQRLETQMSAIASRNSELRLEDVSDVMNG
STQRDKNSAFGSKRPMFSSPLQPDRLRM
Molecule Role Virulence factor
Molecule Role Annotation parasites over expressing LdCK1.4 gave significantly higher infections of mouse peritoneal macrophages compared to wild-type parasites, 28.6% versus 6.3%, respectively (p = 0.0005). These results suggest that LdCK1.4 plays an important role in parasite survival and virulence. (Dan-Goor et al., 2013)
References