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EHI_108720

Victor ID 5183
Gene Name EHI_108720
Sequence Strain (Species/Organism) Entamoeba histolytica HM-1:IMSS
NCBI Gene ID 3405630
NCBI Protein GI 67470724
Locus Tag EHI_108720
Genbank Accession DS571346
Protein Accession XP_651325
Taxonomy ID 294381
Gene Starting Position 16214
Gene Ending Position 17548
Gene Strand (Orientation) -
Protein pI 4.9
Protein Weight 48084.4
Protein Length 444
Protein Note transcript EHI_108720A
DNA Sequence 
>gi|183234256:16214-17548 Entamoeba histolytica HM-1:IMSS scf_1104750517937, whole genome shotgun sequence
TTTAATGATAAAATGTTCCTTTACCAAATTTACCAAAACCATTATTTGGTGTAAAAAAAGTATCAACAGC
ATCTCTTGAAGTTCTCATATCTTCATCTCCAGTTGAGAAATTAAATGTCATACTTTGATTATCATGACTT
TCAATATTATTAAGGTTTTCTTGACCACTTTCATTCTCAGCGAAATCTAAACTCATTCCTAATTCATTTC
CAATGTCTTGGCTCATAGCCATATCAGTTTTTTGAATTGAGTTAAAAACAAATTGAGGTTCTTCCTTTTT
AATTGGTTGTTGAGTTTGAGGAAGTGGAAAATCAGAATTAGTAATTGATTCTTTCTGAATACCCATAGGA
GAAACTAATGTTGGTTGAACAAAAAGACGTTGTGGAACAAGAAGAACATTTTGTTGATCTTCAATAACTG
GTTGTTCACTCATTGCATCACTTTGTTGAATTTGTTCTTCTGAAGGTGAATTAATAGGATTATTAATATC
AATTATTTCTCCTTCTTCAATATCATTATATTCTATTTGATTAGGATTACTAGAAGAGTTATTTGTTAAT
GTAGGTGTAGGAATAATGGGTGTTTCTTTTAATATAGGTACAGCAAGAGAATTAATAATTTTATTATTTG
ATGGAACACTTGATTTTATTGAATCTGGAATAATTAATAGTTGTTCTTGTTGTGTTTTAGGTATAGTTAA
TAATGTATTATTCATATGAATTGATTGTTCTTTTATAATTGTTCCAGAAAGAGGACTTGTAGTCATATTG
ATTCGTTGAGAGTTTATAGTTGTTTTAACATAATTAACTAAATTTTCATTGCATAAGCAAACTCCTTCAT
TAAAATGAGAAACTATATAATTATTTACTGCCATACCAATAGGTTCAATATCTTTTTGTTCTATAATAGG
TTTATTATCTTTTTTAACCATTATTATCTTTTTCATACGAACTGTTTTTTGTGCTTTTCTTGTATTTTTT
TCTCCAAATTCATATCCAAATTTAACAGCTATTTCTACTAATTCATTAAATGCTAATGCAATTTTATTCC
GTTCATATCTTCTAAGTCTTTGTTCAGACTTATCTTCTTCAAGCATTTTAGATGCTTGTGCATTAATACG
ATCAGCAAATTGAATAACATTACCATTATAAATAATTGATTGTACTGGTTGAATTTGATATGTTTTTTCT
GCACTTTTTTTTTGTTTTTTAATTTCTACAGTAACACCAGCACGTGATAATAAGTATATAAGTACTGCTT
GTTGAAAAGACTCAAGGTTCTTTGATTTTTGTTTTGAGATATTTTGTTCATTACGAGGATCGTGATCTTC
TTCCA
Protein Sequence 
>gi|67470724|ref|XP_651325.1| hypothetical protein [Entamoeba histolytica HM-1:IMSS]
MEEDHDPRNEQNISKQKSKNLESFQQAVLIYLLSRAGVTVEIKKQKKSAEKTYQIQPVQSIIYNGNVIQF
ADRINAQASKMLEEDKSEQRLRRYERNKIALAFNELVEIAVKFGYEFGEKNTRKAQKTVRMKKIIMVKKD
NKPIIEQKDIEPIGMAVNNYIVSHFNEGVCLCNENLVNYVKTTINSQRINMTTSPLSGTIIKEQSIHMNN
TLLTIPKTQQEQLLIIPDSIKSSVPSNNKIINSLAVPILKETPIIPTPTLTNNSSSNPNQIEYNDIEEGE
IIDINNPINSPSEEQIQQSDAMSEQPVIEDQQNVLLVPQRLFVQPTLVSPMGIQKESITNSDFPLPQTQQ
PIKKEEPQFVFNSIQKTDMAMSQDIGNELGMSLDFAENESGQENLNNIESHDNQSMTFNFSTGDEDMRTS
RDAVDTFFTPNNGFGKFGKGTFYH
Molecule Role Virulence factor
Molecule Role Annotation EHI_108720, or HRM-binding protein, represents a new stress-responsive transcription factor in E. histolytica that controls a transcriptional regulatory network associated with oxidative stress. Overexpression of EHI_108720 increased parasite virulence.(Pearson et al., 2013)
References