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EHI_188210

Victor ID 5180
Gene Name EHI_188210
Sequence Strain (Species/Organism) Entamoeba histolytica HM-1:IMSS
NCBI Gene ID 3408004
NCBI Protein GI 67476172
Locus Tag EHI_188210
Genbank Accession DS571206
Protein Accession XP_653689
Taxonomy ID 294381
Gene Starting Position 49059
Gene Ending Position 52270
Gene Strand (Orientation) -
Protein Length 1050
Protein Note transcript EHI_188210A
DNA Sequence 
>gi|183232199:49059-52270 Entamoeba histolytica HM-1:IMSS scf_1104750519129, whole genome shotgun sequence
TTTACTCATTTTCTTCATTGATTAAAGAAGTTGGATTTGTTCGAATATACATTGTAGAATCAACAAATAC
ATCTAACTCTTGGTCACAACTTGTTATTGAAATACTTGAGGTTTGGTTATCTATTGAAGATGGTTGTGCA
TCATTTACATGTACATACTTTCTTTTTTTATTAAAATAATATTCTTGAAGTAATTGTGTATTGGTTGGTT
TTATTCTTCTTTGGAAATAAATTGATACGATTTGAGGGAAGACAGTGATAACCATAGAAATAATAATCAT
TAAATAAAAGAGTGGTTGTTTCAATGTAAACAACCACCCCCAATAAGATATATTTCTCACTGACATTCCA
GGGACAAACATAATGATAGTGTAAAGAATAATGTATAATAAAATACTCCCTAAGAACGATAATATAATTG
TATTTCCAACCCGCTTTGTATAAACGAACATAGTTAAATAAATCGAGAAAAGACTGTACGTTGTGACTGT
AACAACTGTGAAAGTAAATCCATTTACTTTTCCATCAAAACTTGTCACGTCTGATGGGGCAATAATGAAA
TAAAATATAACAAAAAAGAGAATTGACTGAAGTCCACCATACAAATACCATTCAACAAAAGACTTAATTT
TGTATTGTTTATCGGTGAATGTTTCTCTATGAGACTTTGGATACAATTTAATAGTTTCCCAAGGAAGTTC
ATAATCAAATAAGGCAATAGCAGCTGGTGGTAGTGAAGTAAAAAATGTATTAAAACAAGTCATAACCCAA
TCATCATAGATAATTTGACAAGTAAAATTGGATATTGTTGCAAACCAAATATCCATAAGAAAGAATGCAG
CATTCTTATAAAAACAAAACTTGATAAGAGTAGTAATTTGGTATTTGCCATTTCTTCCATAAAATAAAAT
TAATTTAGTTAAATGTTTGAATCTTCTAATAGCAAAATCTGCTGTAATAGCGGCTTGATTGCCTTCTTTA
CCATATATCCCAACACCAACATCCCCATGAGTAAGCATTGGAACATCATTTGCACCATCTCCAATTGTAA
GACATTTTGTTTTTGTCATTTGTTTTACACATAAAGCAATATCTGCTTTTTGTTTAGGACTTACTCTACA
ACAAATAACGCTCTCTGCTTTTATAGCAAGAGAACTAAATTTTTTTTGATGTTTAATAAACCAATCAATA
TTATTTTCATGAATAACAATTCCAAGTGTTTGGTTTTGATTTAAAGAATTATCTATTATTTCTTTAGAAC
TATACAACTCTTCTAATTCTTGATCTAAATGTTCAACAAATTCAAGTTCAGAAGTATGATTAAAATATAT
CATCTTTTGTCCAGAAATAAATAATCTACAATTTAATCCAACACTAATAGCTGTTTCCATTTTGTCACCA
GTAATTACCCATATTTTAAGTCCTGCTTCTCTTAGCATTGAAATAGTTGATGGGACATCTTCTTGAAGTT
GATCTTCAATAGCAGTTACACCAATTAATTCTAAATGATTTTCAAGTTGTTCGTATAATTCCATTTGTTG
ACGTTTGATATCATTTGCTAATGGATCAATTGAGTCAAACTTTTGTTTCCATTGAAGAATTTCTTCTGGA
GTAAAAATTCTTCTTGCAATAAAAAGTGTTCTTAGTCCTTCACTTGCAAAATTATTAGCATGAATTTGTG
ATATTTTGACAAGTTCTTTTGAACTATCATCTAAGAGTTGGGTTATTACATTATCAGCTCCTTTACAATA
TAAAATATATAAACCATCTCGTTCTACTAAAACACTCATTCTTTTTCTTGAGCTTGTAAACTCTATTTGA
CATATTAATTTGAATTGTTGATGTTCTCCTAATACATCTAATGAAATATATTCTTGAGTATGTTCTTTTA
AAATTACTCCATTCTTCTTTGAGGCATCACAAAGTGTTTCTTCATCAGGAGAAAATGAAGAATAATTATA
ATCTCCACTATCTGAATGTTCTATGGTACATGAATTACATAGAGATAAACAATAAAGAAAATCAAGTAAT
TTTGGATTATCTACAATTCTTGTTTGAATACTTCCACTAAGAACATTATGATATATTTCACCATAAATAC
TACACTTACTAAACTGCATTTTGTTCTCACTATTTTAATTAAGTTAAAAGGTTTTTTTAATTCAATTTAA
TTATAAAGAAAGACAAACGTTAATGTCCCTGTTTTATCACTTAAAATATACTGAACCCCTCCCATTTCTT
CAATCATTGAACAATTATTTGTTTTCATTCCAACAACTTTTTCTGTACCTTCAGAATCAAATTCTTTAAT
TTTAAAATCATCATCCATTTCCATAATATTTCCTTGAATAAATCTACATACCTCTATTGTAACTCCAACT
GATATTGGAATAGTATATGATATTAAATTAAAATATCCAAAGAACTTTTTTATTGAATAAGTTGTTGTAG
ACCATTGTGGGTCAATTGAATGAAGATACCAATACCCTTCATCTTGTATTACATTTTTATATTTCCAACT
AGCAAATCCTGCCATAATACTACAAAGGATTAATTGAAAGAAAACAGTAGAAAGAACAAATTGATTTAAA
CGATGATCTAATGTTGAATTTTTATTTATTGGTTTTGAAGAATTTAATGATTGTTTAGTATATTTTCCTG
TATAACATACTACAGCAATAACTTTATCAGTTTTTCTTAAAACAGAACCTTGTAATAAAAGGTTTTTTGA
ATCTAATGTTATTATATTCTCTCCATTAAACTTAAAACACCCTTTAAAGTCATTAAAATTTGATGTAGGA
AATCCACACTCTAACATTCCTTTAAAATCAAGTGTTGAATTTTCTGAACTTTTAGATAATTGTTTGGGGA
CATAAACTGTTTTCAATGATGTTTCTCCATCTAATGCAGCTGTTTCTACTTTACAAATACCATCAGGTAA
AGAAGAATAAATAGGTACACAATCACAAGGTATAATTTCATTCTTAGTTAAAATAACTAAATCCCCAACA
ACAATATTCTTGGACGATCTAATAGTCTCAATTCCATCAGTAATAGTACTAAACTTTTTATTATTAAATT
CTTTATCTGAACGATGTCTTTTTAAATCTTCGATAATTTCTCTTATTGCTGAAACACAAAGAACAATAAT
AATTGGAATAACAGCAGTAATTGGTGTTACTGTTGAAATAAAAGGAATACAACTAATTATCA
Protein Sequence 
>gi|67476172|ref|XP_653689.1| phospholipid-transporting P-type ATPase [Entamoeba histolytica HM-1:IMSS]
MIISCIPFISTVTPITAVIPIIIVLCVSAIREIIEDLKRHRSDKEFNNKKFSTITDGIETIRSSKNIVVG
DLVILTKNEIIPCDCVPIYSSLPDGICKVETAALDGETSLKTVYVPKQLSKSSENSTLDFKGMLECGFPT
SNFNDFKGCFKFNGENIITLDSKNLLLQGSVLRKTDKVIAVVCYTGKYTKQSLNSSKPINKNSTLDHRLN
QFVLSTVFFQLILCSIMAGFASWKYKNVIQDEGYWYLHSIDPQWSTTTYSIKKFFGYFNLISYTIPISVG
VTIEVCRFIQGNIMEMDDDFKIKEFDSEGTEKVVGMKTNNCSMIEEMGGVQYILSDKTGTLTENKMQFSK
CSIYGEIYHNVLSGSIQTRIVDNPKLLDFLYCLSLCNSCTIEHSDSGDYNYSSFSPDEETLCDASKKNGV
ILKEHTQEYISLDVLGEHQQFKLICQIEFTSSRKRMSVLVERDGLYILYCKGADNVITQLLDDSSKELVK
ISQIHANNFASEGLRTLFIARRIFTPEEILQWKQKFDSIDPLANDIKRQQMELYEQLENHLELIGVTAIE
DQLQEDVPSTISMLREAGLKIWVITGDKMETAISVGLNCRLFISGQKMIYFNHTSELEFVEHLDQELEEL
YSSKEIIDNSLNQNQTLGIVIHENNIDWFIKHQKKFSSLAIKAESVICCRVSPKQKADIALCVKQMTKTK
CLTIGDGANDVPMLTHGDVGVGIYGKEGNQAAITADFAIRRFKHLTKLILFYGRNGKYQITTLIKFCFYK
NAAFFLMDIWFATISNFTCQIIYDDWVMTCFNTFFTSLPPAAIALFDYELPWETIKLYPKSHRETFTDKQ
YKIKSFVEWYLYGGLQSILFFVIFYFIIAPSDVTSFDGKVNGFTFTVVTVTTYSLFSIYLTMFVYTKRVG
NTIILSFLGSILLYIILYTIIMFVPGMSVRNISYWGWLFTLKQPLFYLMIIISMVITVFPQIVSIYFQRR
IKPTNTQLLQEYYFNKKRKYVHVNDAQPSSIDNQTSSISITSCDQELDVFVDSTMYIRTNPTSLINEENE
Molecule Role Virulence factor
Molecule Role Annotation we have confirmed that two genes that are upregulated by ROS confer increased resistance to oxidative stress and have identified an unexpected role of EhSIAF and EhPTPA in host cell adherence and a role of EhSIAF in parasite virulence.(Rastew et al., 2012)
References