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lmo1076

Victor ID 518
Gene Name lmo1076
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 986264
NCBI Protein GI 16803116
Locus Tag lmo1076
Protein Accession NP_464601.1
Other Database IDs UniProtKB-ID: Q8Y842_LISMO
UniRef100: UniRef100_C8JVJ5
UniRef90: UniRef90_D3ULY4
UniRef50: UniRef50_D3ULY4
UniParc: UPI0000054CB2
EMBL: AL591977
EMBL-CDS: CAC99154.1
RefSeq_NT: NC_003210.1
PDB: 3FI7
GenomeReviews: AL591824_GR
KEGG: lmo:lmo1076
GenoList: LMO1076
ProtClustDB: CLSK564251
BioCyc: LMON169963:LMO1076-MONOMER
Taxonomy ID 169963
Gene Starting Position 1106040
Gene Ending Position 1107758
Gene Strand (Orientation) +
Protein Name similar to autolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)
DNA Sequence 
>gi|16802048:1106040-1107758 Listeria monocytogenes EGD-e, complete genome
AATGATTAAAAAAGTTTTTCATTTTATACTTGTACTGATGTTAAGTGTAAGTATAATACCTCTATTCCAT
GCTAAAGCAGCTGAAACAACTAATGGAGTAGATAGTAGTGAACAGGAAGATAATACCGAAGTTGCGCGTG
AAGAAATGCCTCCAGAGTCTGAGGAACCAGTATTCTCGCTTGAACAAAATAGAGATGATGCTATGGCTGC
TTTAGTCGTGCCTCAAACTAGAAATAGTTTTTTGAGAGCAGCTAGTACTCCGACATTTCAACAAACATTT
ATAAATTCCATTTCCACGCAAGCAATGGATTTATGTAAAAAGTACAATTTATATCCATCTGTAATGATTG
CTCAAGCGGCTCTTGAGAGTAACTGGGGAAGAAGTGAATTAGGGAAGGCCCCTAATTACAACTTGTTTGG
AATAAAAGGATCATATAATGGCAAAAGTGTAACAATGAAAACTTGGGAATATAGTGATTCCAAAGGTTGG
TATCAAATCAACGCAAACTTTGCCAAATACCCATCACACAAAGAATCTTTAGAAGACAATGCGAAAAAAC
TTAGAAATGGCCCAAGTTGGGACTCTAGTTATTACAAAGGTGCATGGCGCGAGAATGCAAAAACATACAA
AGATGCGACTGCATGGTTACAGGGACGTTATGCAACGGACAACACATATGCTTCTAAGCTAAATACGCTA
ATTTCTTCATATAATTTGACTCAATATGATACTCTGTACGATACGATTAAACAACAAAAAAATGTTTCTG
AAGATGCTAAAGTAGTTAAAGCAGATGGGCATGGTGTTTATAGTGGAATTTACAATACGTCTGCAGCCAG
TGCGAAAAAGTTATCTACTGGAGCGCCTTACAACAATAAAGATGTAAAAATTTTAAAAGAAGGCACTACA
AGCAGAGGAACGTGGGTCCAATTTTCTCTCAATAATAAAGTAATCGGCTGGATGGATAAACGCGCATTTG
TCTATTATCCAAAAGCAACAAATGTAAAAACGCTTAACCTAACAGGTAAAATCACTGCTGGATCTACTAA
TGGTTTATGGTCTGAGGTTCCAGGTACAGTGAATGCGAAAAAATTAGCTACAACAGCTGGTGCTTACCAA
AATAAAGATGCTAAAATTATTAAGCAAGGTCAAATTAGTGGCCGAACTTACTATCAATTCCAAGTAGGCG
GTAAAACAATTGGTTGGTTGGACGCTCGTGCATTTCATGTTTATGATAAAATCCAAAGCCAGTCAAATGT
AAATTGGAATCGAACTATTTTAAATGCCGATAAGCACGGTGTGTACTCGGGTGTTTATAATACTTCATCA
AGTAGTATGAATAAACTAAGTACAGGCGCGAAATATAATAATAAAAAAGTAAAAGTTATTAAGCAAGCCA
AGACCGCGCGTGGAACTTGGTATCAATTCCAAGTAAATGGCAAAACAGTTGGTTGGATGGATTATCGTGC
ATTCTTTGACACAATTACCTCCCAAAAAACAATGAATAAAACAGTTACTGTGGGTAATGCCACGAATCAT
GGCGTTTTTGATGGGGTTTATCGAACCTCGCCAACGGTAAAACGAATTTCTTTGGGGAAACCATACAATA
ATAAAAAAGTAAAAGTGCTCAAAGAAGCTGTAACAGACCATGCCACATGGGTTCAATTTAAATACGGTAA
CACAACTGCATGGATGGACAAAAAAGCATTTAAATATTA
Protein Sequence 
>gi|16803116|ref|NP_464601.1| autolysin [Listeria monocytogenes EGD-e] MIKKVFHFILVLMLSVSIIPLFHAKAAETTNGVDSSEQEDNTEVAREEMPPESEEPVFSLEQNRDDAMAALVVPQTRNSFLRAASTPTFQQTFINSISTQAMDLCKKYNLYPSVMIAQAALESNWGRSELGKAPNYNLFGIKGSYNGKSVTMKTWEYSDSKGWYQINANFAKYPSHKESLEDNAKKLRNGPSWDSSYYKGAWRENAKTYKDATAWLQGRYATDNTYASKLNTLISSYNLTQYDTLYDTIKQQKNVSEDAKVVKADGHGVYSGIYNTSAASAKKLSTGAPYNNKDVKILKEGTTSRGTWVQFSLNNKVIGWMDKRAFVYYPKATNVKTLNLTGKITAGSTNGLWSEVPGTVNAKKLATTAGAYQNKDAKIIKQGQISGRTYYQFQVGGKTIGWLDARAFHVYDKIQSQSNVNWNRTILNADKHGVYSGVYNTSSSSMNKLSTGAKYNNKKVKVIKQAKTARGTWYQFQVNGKTVGWMDYRAFFDTITSQKTMNKTVTVGNATNHGVFDGVYRTSPTVKRISLGKPYNNKKVKVLKEAVTDHATWVQFKYGNTTAWMDKKAFKY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aut deletion mutants show reduced invasiveness and virulence in mice and guinea pigs (Cabanes et al., 2004).
COG COG1705NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Cabanes et al., 2004: Cabanes D, Dussurget O, Dehoux P, Cossart P. Auto, a surface associated autolysin of Listeria monocytogenes required for entry into eukaryotic cells and virulence. Molecular microbiology. 2004; 51(6); 1601-1614. [PubMed: 15009888].