Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

CP5

Victor ID 5177
Gene Name CP5
NCBI Protein GI 114796866
Other Database IDs CDD:214853
CDD:239068
Taxonomy ID 5759
Gene Strand (Orientation) ?
Protein Name cysteine proteinase 5
Protein Length 289
Protein Note Cathepsin propeptide inhibitor domain (I29); smart00848
Protein Sequence 
>gi|114796866|gb|ABI79445.1| cysteine proteinase 5, partial [Entamoeba histolytica]
NTWVANNNKHFTIVETLRRRAIFNNNARFIAKFNKNNSFQLSVEGPFAAMTEAEYNSMLKPFVIDKQHEE
IVYDSRGDVPESVDWRAKGKVPAIRDQASCGSCYSFASVAAIEGRLLVAGSKKFTVDDLDLSEQQLVDCS
VSVGNKGCNGGSLLLSFRYVKLNGIMQEKDYPYVAAEETCTYDKKKVAVKITGQKLVRPGSEKALMRAAA
EGPVGAAIDASGVKFQLYKSGIYNSKECSSTQLNHGVAVVGYGTQNGTEYWIVRNSWGTIWGDQGYVLMS
RNKNNQCGI
Molecule Role Virulence factor
Molecule Role Annotation transfection and overexpression of ehcp5 was able to compensate the reduction of in vivo pathogenicity in parasites, which have been silenced for the gene encoding the pore-forming protein amoebapore A. In summary, these results further support the important role of EhCP5 in E. histolytica pathogenicity.(Tillack et al., 2006)
References