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FIKK4.1

Victor ID 5172
Gene Name FIKK4.1
Sequence Strain (Species/Organism) Plasmodium falciparum 3D7
NCBI Gene ID 812596
NCBI Protein GI 124505613
Locus Tag PFD1165w
Genbank Accession AL844503
Protein Accession XP_001351548
Taxonomy ID 36329
Chromosome No 4
Gene Starting Position 1113688
Gene Ending Position 1115921
Gene Strand (Orientation) ?
Protein pI 9.29
Protein Weight 71761.05
Protein Length 622
Protein Note Also known as FIKK 4.1; FIKK-4.1; PfTSTK4a; TSTK4a
DNA Sequence 
>gi|23509994:1113688-1115921 Plasmodium falciparum 3D7 chromosome 4
AATGAAGAAAAAAACAAGGGAAGAAATAATAATATTCTTAAAATGGGTGTCTTGTAAAAAATATATATTT
TCAGTTTTTGTGTTTTTATGTTGCTTTTTAATGGTAATGATAAAATAAAATAAAAAAAAAAAAAAAAATA
TATATATATATATATATATTTATTTATTTATTTATATGTTCTGTTGAGGCCTCTCTTATTAATTATGTTC
TATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTA
TATTATATTTTATTTTGTTTTATTTTTTTTCTGTTTTATTTTAGAGCTTCAACATATTTGAACCCAGAAT
CGAAATAATAGAATTGAATTGGCATGTTAGATACTATAGACATTTAACCGAAGTATGGGATAATAATAAT
AATAATGATGAGGGAGAACAGAATTTAAAGGATAAGTATGATACATATGATGAGAAGGAAAAAGTGAAGA
AAAAATATGTAGAAGATGAATTTAATACGAAGGAAAAAGTGAAGAAAAAACATAGAGATGATAAATATAA
TAAGAAGGAAAAATCGAAGAAAAAACATAGAGATGATAAATATAATAAGAAGGAAAAATCGAAGAAAAAA
TATGTAGAAGATAAATTTAATAAGAAAAACAAGCATAAAGAAAATGATGTAAGTTTGAAGAAAGACCAAT
GTAAAAAATCATTGTCCATAAGAGAAGATTGTAATAATAAAAATAGTAAATCTTATAATGAAAAGGAAAT
ATGTGATAATGAAAATTGTGTTAATTTAGAAGATATAAAAATATATGATAATACAACATGGAAATATAAA
ATAAAAAAGTTGATAACATGTTCATATAATTCAGATAAAGATGCAAAGGTTTTATATAATTGGAAACTAG
GAAAAAGTATTTTAGGTAAAATGATAAATAGTACAGAAGACTTTAGTATTAATGGTATAAGTTATAAAGA
TTGGACTTTAAATACAATACCGGATATAGGTTATTCACAAAACAATCGTAGATCCCAAGAAGTATTTAAA
ACTGAAGTAAAATCAAAGGATGAAAATACGGAAAGTGTGAAATTATTTATTAAAAAGGTACCTGCAAGTA
TTTGGGTTCGACAATATATTATATTAAATGAACATAAAGGGGAATATTCATTAGGTGAAGAGAATTTTGT
TATGGAAGCTATTTCATTAGCTTTTTTAAATAAATATTATCCAGGTATCGCTCCAAAATTTTATGGTATA
TTATATGAGTCACCTGATAAACCTAATGATAATGTATGTTTTTCTTTTGGAAGAGGTAAGTGTAATAATT
TGAAAAAGTTTAATGATATGCTCATAAATCAATTACAATTGAATAACAAGGCAAATGTTATTATGATCTC
TGAATTATATGGAGAAGATGTTTTTAAATATGTAAAGAATAAAAGAAAGGAAGGTTGTTTTGGTAATAAC
CTGGAAGAGAAAAAAAAGATTCTACATGAAAGTTTAAAATTAATAACAACATTACATGAAACTGGATTAA
GTCATTTAGATATTTCTCCAGAAAATATATTAATAGGTAATAATTGTGAATTGAAGTTATGTGATTTTGC
AAATAGTGCTCCTATTTATACTTATAATAATAGACATCTAAAAGGTAATAAACGTTTACGATATTATGAA
TCTTATCAACCATGTATATCGAAGGTTCCTTTACTCCCACCAGAATGTTGGAATATTGTTCGAATACATG
AGAAATTAAAAATCAATGACCCTTATGATTATCTAAAATCTATTACTAATCAAGAAGAAAGAAAATCGTT
CTATTTCAATGTATCAAATGCTGATAAATTTATGTTAGGAATATTTTTTATTTGGGTATGGAATAATAAC
TATATATGGGAAAAGGCAGATTCATTTAATGATAGAAAGTTTAGGAATTTTGTAAAATGTGGAATGGATC
TTTATAATTATGAATTAACATATAACTGGCCGGATGATCTCAAGGATATAATAAACGTAAAAAGGAAAAT
GAAAAAATGAATAAATAAAAAAAAAAATAAGTGAATAAAAAAATATAATGCTTCATATATTATACACAAA
CATATATATATGTATATATATATATATATTTTTTTTTTTTTTTTTTTTTTTTTTTTGTAGCAATTATTAC
CCTTGGAAAATCGTGCGCAATTAAGCCTGAAGGAATTATGTAAGCATCCCTGGTGGTCTAACTA
Protein Sequence 
>gi|124505613|ref|XP_001351548.1| Serine/Threonine protein kinase, FIKK family [Plasmodium falciparum 3D7]
MKKKTREEIIIFLKWVSCKKYIFSVFVFLCCFLMSFNIFEPRIEIIELNWHVRYYRHLTEVWDNNNNNDE
GEQNLKDKYDTYDEKEKVKKKYVEDEFNTKEKVKKKHRDDKYNKKEKSKKKHRDDKYNKKEKSKKKYVED
KFNKKNKHKENDVSLKKDQCKKSLSIREDCNNKNSKSYNEKEICDNENCVNLEDIKIYDNTTWKYKIKKL
ITCSYNSDKDAKVLYNWKLGKSILGKMINSTEDFSINGISYKDWTLNTIPDIGYSQNNRRSQEVFKTEVK
SKDENTESVKLFIKKVPASIWVRQYIILNEHKGEYSLGEENFVMEAISLAFLNKYYPGIAPKFYGILYES
PDKPNDNVCFSFGRGKCNNLKKFNDMLINQLQLNNKANVIMISELYGEDVFKYVKNKRKEGCFGNNLEEK
KKILHESLKLITTLHETGLSHLDISPENILIGNNCELKLCDFANSAPIYTYNNRHLKGNKRLRYYESYQP
CISKVPLLPPECWNIVRIHEKLKINDPYDYLKSITNQEERKSFYFNVSNADKFMLGIFFIWVWNNNYIWE
KADSFNDRKFRNFVKCGMDLYNYELTYNWPDDLKDIINQLLPLENRAQLSLKELCKHPWWSN
Molecule Role Virulence factor
Molecule Role Annotation targeted disruption of the gene encoding FIKK4.2 (fikk4.2) dramatically alters the parasites ability to modify and remodel the red blood cells in which it multiplies.
(Kats et al., 2014)
References