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MIC3

Victor ID 5161
Gene Name MIC3
Sequence Strain (Species/Organism) Toxoplasma gondii ME49
NCBI Gene ID 7901253
NCBI Protein GI 237841071
Locus Tag TGME49_119560
Genbank Accession DS984741
Protein Accession XP_002369833
Taxonomy ID 508771
Gene Starting Position 639397
Gene Ending Position 641077
Gene Strand (Orientation) -
Protein pI 6.42
Protein Weight 35799.15
Protein Length 359
DNA Sequence 
>gi|212659403:639397-641077 Toxoplasma gondii ME49 scf_1112359875140, whole genome shotgun sequence
TGCCGGCCCCGTCAAGGGCAAAGCTGTACAGTTACATAAAGGTCAGTTTGTGTCGGTTTTATACAGACGG
CGATGATTGCATGCACGGACAGCTGCGAATGGGCGCATTCTCCAATGCTAAAGTAAAGGACAGACTCCAG
CTCACTGCTTAATTTTCTCACACGTCACGGTGTGGGCATGGTATCTTGGATGGTAGCCACTGGGGCACTT
GAAGACAATATTCATTTTTTCACTCAAGCTCCCCTCGGATCCCGATTCTCCTTTCCCATGGTGGGAGGTT
GCGGAAGCAGATCCGGAGTATCCGTTATCGCATTTGCAGGATGACGCGCTGATGCCGAATTCCTTCTCGC
ATTTCTCAGCCAGCGTGACTTCGACTCCTTCCACACACGACTCCTCCGCCTTGGAAGTCACCTCACGTGA
GTACCCTGTGGGGCACTCGCAGGTGTAGCCATTCTCATGCGAGGCGTCATCAATACATCTACCAGGGCTG
CAGTTCTCCCTGAAGGCATGACATCCAGTCCTCTTGCATCCTTGTCCCCCTTCCGGGAGGTTCACTAGAG
TTTCGCCGTCGCCGCAGGTGCATGTGTAGCTGACTGAATCGACGACGATGCACGTCCCGTTGGGTCCGCA
CTTCGCGTTCCCTCTTTTTGAACAAGGATCCTCGGAGCAAGTCAACCCAGTGCCGACGAAGCCGTCTTTG
CACTTGCAGTGCACACCCCCACCCGCGTCCAAGTTTTCGACGCATTCTGCGTTTTTGTCGCACCGATGGC
CCTGCTTTTCACAGCTGCAGTCTCCTCCATAGCTTTTGTCAGGATGGTAGATGAGCGAACTGCTGCAAAA
AATCCAGTTGCTGGAGCAGAATTCTCCGCAGCCGCCGGGGCCGCACATGGTCTTGCTGCAGCAAGCGCTC
TTGGGGCAACTGGCCCCGATGAAGTACCCGTTGTCAGTGTGCAACTGACGGTTTCGACATGGCTTGCCTT
CACTCGAGATAGCACAGAGTTGCGTCTCCTGCTTGCTGGGGGATTGCACAGACGAGTGAGTCTCAGTCAC
CGCGAAAGACGGAGCAAGACTCTCAGAGACGACTTCGCGGCTCGGCACAACTTTGTCAAAGCTGCCCAGC
TGCACAGACTTCTGAATCGGCAAAGCCTCCGCTGGGGTGCACATCCACACGGCCCCACTGAAGGTGAGCG
CGTGCAACAGCGCGGACGTCCCGCCTCGCATTTTTACCAGTGTTGGACAAGGAAGTTACACACAGAGTAA
GGCGCGCAAACGCGCTGCACTGCCCACAGAAATGCACAGAAACGCACTCTCGACGAGCTGCGACCCACCG
CCCGCAAACGTCTTCCCGGAAAAGGTGTGTGTGTGATGGCTGGTTCGAGGGAACCTATCGATTGCGCTAG
CAGCAAGTTGAGTGACAGCGTGCGTCGTGCGACAGGGCAAGTGTACCAAAAGTCACATCGGAGGTGTACC
GGTGAACGAAGGAGGTTAGAAACAGAAGTGACACGAGCTAGACTCGACCAGAGAGTCTTTTTTCACCGAG
CAAGGGGACGCAATGCTGCTGACTCGATGAACGCTCTTCAGTCCCGGCTGGCGACGTCGAGCAACTGGCC
GGTCATTGCGACGCGAGAATGCGACGCGAGAATGCGACGCGACACACCAGAGACCCGTGGTCTCCTATTT
A
Protein Sequence 
>gi|237841071|ref|XP_002369833.1| microneme protein MIC3 [Toxoplasma gondii ME49]
MRGGTSALLHALTFSGAVWMCTPAEALPIQKSVQLGSFDKVVPSREVVSESLAPSFAVTETHSSVQSPSK
QETQLCAISSEGKPCRNRQLHTDNGYFIGASCPKSACCSKTMCGPGGCGEFCSSNWIFCSSSLIYHPDKS
YGGDCSCEKQGHRCDKNAECVENLDAGGGVHCKCKDGFVGTGLTCSEDPCSKRGNAKCGPNGTCIVVDSV
SYTCTCGDGETLVNLPEGGQGCKRTGCHAFRENCSPGRCIDDASHENGYTCECPTGYSREVTSKAEESCV
EGVEVTLAEKCEKEFGISASSCKCDNGYSGSASATSHHGKGESGSEGSLSEKMNIVFKCPSGYHPRYHAH
TVTCEKIKQ
Molecule Role Virulence factor
Molecule Role Annotation Individual disruption of MIC1 or MIC3 genes slightly reduced virulence in the mouse, whereas doubly depleted parasites were severely impaired in virulence and conferred protection against subsequent challenge. (Cérède et al., 2005)
References